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J Clin Biochem Nutr :口腔微生物的水平与BMI有关

2015-10-11 sunshine 译 MedSci原创

J Clin Biochem Nutr :口腔中红色复合体的水平与BMI有关微生物一直被认为是肥胖及2型糖尿病的一个重要的环境影响因素。口腔菌群中,所谓的红色复合体即牙龈卟啉单胞菌、齿垢密螺旋体以及福赛坦氏菌是已知的导致牙周炎发生的危险因素。红色复合体还可能是导致肥胖的危险因素。然而,最近的研究表明,肥胖患者经牙周治疗后并不会改善其机体的肥胖状况。因此,本研究进行了一次横断面调查研究,以揭示健康人

微生物一直被认为是肥胖及2型糖尿病的一个重要的环境影响因素。口腔菌群中,所谓的红色复合体(即牙龈卟啉单胞菌、齿垢密螺旋体以及福赛坦氏菌)是已知的导致牙周炎发生的危险因素。红色复合体还可能是导致肥胖的危险因素。然而,最近的研究表明,肥胖患者经牙周治疗后并不会改善其机体的肥胖状况。因此,本研究进行了一次横断面调查研究,以揭示健康人群中口腔微生物与身体质量指数之间的关系。

本研究随机招募了222名健康的日本志愿者。使用聚合酶链式反应确定研究对象的口腔微生物感染状况。分析所有研究对象口腔中红色复合体的水平与身体质量指数或腰围之间的关系。校正混杂因素后,身体质量指数及腰围以及年龄、牙周炎,刷牙次数与红色复合体的水平具有显著的相关关系。身体质量指数及腰围的影响大小分别为0.023 (p = 0.028) 和0.024 (p = 0.024)。健康研究对象中,身体质量指数和腰围与其口腔中红色复合体的水平独立相关。

总之,目前的观察性研究显示,健康人群中,口腔微生物或可与机体的肥胖状态有关。

原始出处:

Matsushita K, Hamaguchi M et al.The novel association between red complex of oral microbe and body mass index in healthy Japanese: a population based cross-sectional study. J Clin Biochem Nutr. 2015 Sep;57(2):135-9. doi: 10.3164/jcbn.15-19.

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    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=125012, encodeId=2de0125012cd, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:45:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917197, encodeId=d208191e19773, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Mon Feb 22 12:43:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824609, encodeId=60e3182460968, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Mar 04 13:43:00 CST 2016, time=2016-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47086, encodeId=01994e08685, content=肥胖, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:09:00 CST 2015, time=2015-12-22, status=1, ipAttribution=)]
    2016-02-22 sunylz
  3. [GetPortalCommentsPageByObjectIdResponse(id=125012, encodeId=2de0125012cd, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:45:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917197, encodeId=d208191e19773, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Mon Feb 22 12:43:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824609, encodeId=60e3182460968, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Mar 04 13:43:00 CST 2016, time=2016-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47086, encodeId=01994e08685, content=肥胖, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:09:00 CST 2015, time=2015-12-22, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=125012, encodeId=2de0125012cd, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:45:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1917197, encodeId=d208191e19773, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Mon Feb 22 12:43:00 CST 2016, time=2016-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824609, encodeId=60e3182460968, content=<a href='/topic/show?id=702a5065860' target=_blank style='color:#2F92EE;'>#微生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50658, encryptionId=702a5065860, topicName=微生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Fri Mar 04 13:43:00 CST 2016, time=2016-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47086, encodeId=01994e08685, content=肥胖, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Tue Dec 22 17:09:00 CST 2015, time=2015-12-22, status=1, ipAttribution=)]
    2015-12-22 xiaotaiyang1

    肥胖

    0

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