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Kidney Int:亚太裔IgA肾病患者更易发生ESRD

2013-11-28 佚名 医学论坛网

加拿大一项研究表明,与其他族裔IgA肾病患者相比,亚太裔患者进展至终末期肾脏病(ESRD)的风险升高。 研究分别纳入202例自报为亚太裔的IgA肾病患者以及467例其他族裔患者。发展至ESRD是指需要透析、移植或估计的肾小球滤过率(eGFR)<15 ml/(min/1.73m2)。 结果显示,受试者的基线eGFR为59.6 ml/(min/1.73m2),中位蛋

加拿大一项研究表明,与其他族裔IgA肾病患者相比,亚太裔患者进展至终末期肾脏病(ESRD)的风险升高。

研究分别纳入202例自报为亚太裔的IgA肾病患者以及467例其他族裔患者。发展至ESRD是指需要透析、移植或估计的肾小球滤过率(eGFR)<15 ml/(min/1.73m2)。【原文下载

结果显示,受试者的基线eGFR为59.6 ml/(min/1.73m2),中位蛋白尿为1.8 g/d。随访期间,213例患者出现ESRD。单变量分析显示,两组患者的ESRD风险相似[危险比(HR)=0.98]。然而,对年龄、性别、eGFR、药物应用、血压和蛋白尿进行校正后,亚太裔患者的ESRD风险显著升高(HR= 1.56)。

原文出处

Barbour SJ, Cattran DC, Kim SJ, Levin A, Wald R, Hladunewich MA, Reich HN.Individuals of Pacific Asian origin with IgA nephropathy have an increased risk of progression to end-stage renal disease.Kidney Int. 2013 Nov【原文下载

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    2017-05-06 laymankey

    感谢分享一下!!

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=194623, encodeId=dbdd1946239a, content=感谢分享一下!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20971999626, createdName=laymankey, createdTime=Sat May 06 15:07:54 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1687534, encodeId=b365168e534fa, content=<a href='/topic/show?id=0ea224245e4' target=_blank style='color:#2F92EE;'>#亚太#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24245, encryptionId=0ea224245e4, topicName=亚太)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ef428388125, createdName=ms2536978994064944, createdTime=Tue Dec 10 14:20:00 CST 2013, time=2013-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028107, encodeId=c5ae202810e08, content=<a href='/topic/show?id=99ff9483cd' target=_blank style='color:#2F92EE;'>#IgA肾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9483, encryptionId=99ff9483cd, topicName=IgA肾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Tue Jun 03 04:20:00 CST 2014, time=2014-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2025771, encodeId=81c52025e7128, content=<a href='/topic/show?id=a91d82583bf' target=_blank style='color:#2F92EE;'>#肾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82583, encryptionId=a91d82583bf, topicName=肾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=db5b227, createdName=gostraight, createdTime=Mon Jan 27 20:20:00 CST 2014, time=2014-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398924, encodeId=ce4d139892482, content=<a href='/topic/show?id=6739e04128' target=_blank style='color:#2F92EE;'>#ESRD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7041, encryptionId=6739e04128, topicName=ESRD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414591, encodeId=ab7c1414591a4, content=<a href='/topic/show?id=c83e94827d' target=_blank style='color:#2F92EE;'>#IgA肾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9482, encryptionId=c83e94827d, topicName=IgA肾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd7c3073380, createdName=huiwelcome, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503881, encodeId=60cc1503881bd, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602948, encodeId=fda716029486f, content=<a href='/topic/show?id=81b91049067' target=_blank style='color:#2F92EE;'>#kidney#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10490, encryptionId=81b91049067, topicName=kidney)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c36e18990621, createdName=gwc389, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=)]
    2013-11-30 yige2004
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  7. [GetPortalCommentsPageByObjectIdResponse(id=194623, encodeId=dbdd1946239a, content=感谢分享一下!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20971999626, createdName=laymankey, createdTime=Sat May 06 15:07:54 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1687534, encodeId=b365168e534fa, content=<a href='/topic/show?id=0ea224245e4' target=_blank style='color:#2F92EE;'>#亚太#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24245, encryptionId=0ea224245e4, topicName=亚太)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ef428388125, createdName=ms2536978994064944, createdTime=Tue Dec 10 14:20:00 CST 2013, time=2013-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028107, encodeId=c5ae202810e08, content=<a href='/topic/show?id=99ff9483cd' target=_blank style='color:#2F92EE;'>#IgA肾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9483, encryptionId=99ff9483cd, topicName=IgA肾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Tue Jun 03 04:20:00 CST 2014, time=2014-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2025771, encodeId=81c52025e7128, content=<a href='/topic/show?id=a91d82583bf' target=_blank style='color:#2F92EE;'>#肾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82583, encryptionId=a91d82583bf, topicName=肾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=db5b227, createdName=gostraight, createdTime=Mon Jan 27 20:20:00 CST 2014, time=2014-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398924, encodeId=ce4d139892482, content=<a href='/topic/show?id=6739e04128' target=_blank style='color:#2F92EE;'>#ESRD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7041, encryptionId=6739e04128, topicName=ESRD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414591, encodeId=ab7c1414591a4, content=<a href='/topic/show?id=c83e94827d' target=_blank style='color:#2F92EE;'>#IgA肾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9482, encryptionId=c83e94827d, topicName=IgA肾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd7c3073380, createdName=huiwelcome, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503881, encodeId=60cc1503881bd, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602948, encodeId=fda716029486f, content=<a href='/topic/show?id=81b91049067' target=_blank style='color:#2F92EE;'>#kidney#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10490, encryptionId=81b91049067, topicName=kidney)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c36e18990621, createdName=gwc389, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=)]
    2013-11-30 yibei
  8. [GetPortalCommentsPageByObjectIdResponse(id=194623, encodeId=dbdd1946239a, content=感谢分享一下!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20971999626, createdName=laymankey, createdTime=Sat May 06 15:07:54 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1687534, encodeId=b365168e534fa, content=<a href='/topic/show?id=0ea224245e4' target=_blank style='color:#2F92EE;'>#亚太#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24245, encryptionId=0ea224245e4, topicName=亚太)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ef428388125, createdName=ms2536978994064944, createdTime=Tue Dec 10 14:20:00 CST 2013, time=2013-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2028107, encodeId=c5ae202810e08, content=<a href='/topic/show?id=99ff9483cd' target=_blank style='color:#2F92EE;'>#IgA肾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9483, encryptionId=99ff9483cd, topicName=IgA肾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Tue Jun 03 04:20:00 CST 2014, time=2014-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2025771, encodeId=81c52025e7128, content=<a href='/topic/show?id=a91d82583bf' target=_blank style='color:#2F92EE;'>#肾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82583, encryptionId=a91d82583bf, topicName=肾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=db5b227, createdName=gostraight, createdTime=Mon Jan 27 20:20:00 CST 2014, time=2014-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398924, encodeId=ce4d139892482, content=<a href='/topic/show?id=6739e04128' target=_blank style='color:#2F92EE;'>#ESRD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7041, encryptionId=6739e04128, topicName=ESRD)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414591, encodeId=ab7c1414591a4, content=<a href='/topic/show?id=c83e94827d' target=_blank style='color:#2F92EE;'>#IgA肾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9482, encryptionId=c83e94827d, topicName=IgA肾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd7c3073380, createdName=huiwelcome, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503881, encodeId=60cc1503881bd, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602948, encodeId=fda716029486f, content=<a href='/topic/show?id=81b91049067' target=_blank style='color:#2F92EE;'>#kidney#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10490, encryptionId=81b91049067, topicName=kidney)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c36e18990621, createdName=gwc389, createdTime=Sat Nov 30 06:20:00 CST 2013, time=2013-11-30, status=1, ipAttribution=)]
    2013-11-30 gwc389

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