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盘点:世界上9种致命的病毒

2016-11-07 解螺旋·医生科研助手 解螺旋·医生科研助手

自古以来,病毒一直都是威胁人类健康的“隐形杀手”。而在与病毒的斗争,人类似乎占据了上风、赢得了阶段性的胜利,比如天花病毒的彻底根除,且数十年来再无新发案例。但是埃博拉病毒的爆发,打的我们措手不及,这也说明了要想真正战胜病毒还有很长的路要走。更何况世界上同样致命的病毒也有很多,某些甚至有过之而无不及,本文则根据历史上人感染后的致死率,盘点了世界上病毒排行榜上最致命的9种。NO.1 马尔堡病毒(M



自古以来,病毒一直都是威胁人类健康的“隐形杀手”。而在与病毒的斗争,人类似乎占据了上风、赢得了阶段性的胜利,比如天花病毒的彻底根除,且数十年来再无新发案例。但是埃博拉病毒的爆发,打的我们措手不及,这也说明了要想真正战胜病毒还有很长的路要走。更何况世界上同样致命的病毒也有很多,某些甚至有过之而无不及,本文则根据历史上人感染后的致死率,盘点了世界上病毒排行榜上最致命的9种。


NO.1 马尔堡病毒(Marburg virus)



马尔堡病毒和埃博拉病毒可谓是“同门师兄弟”,所到之处,无不寸草不生,让人胆颤心惊。这两种病毒属于同一家族——纤维病毒家族,均能造成出血热,严重时可导致休克、器官衰竭和死亡等症状。 马尔堡病毒首次于1967年被发现,且其第一次爆发时所产生的致死率是25%,但根据国际卫生组织(WHO)资料,1998-2000年在刚果民主共和国和2005年在安哥拉的爆发致死率均超过了80%,可以说是无愧于最致命病毒的称号。

NO.2 埃博拉病毒(Ebola virus)



埃博拉病毒既然和马尔堡病毒“一脉同源”,那么其致命性也是毋庸置疑的。每次其在世上猖狂肆虐时,都会收割大把生命;而且每次爆发都有种“神不知鬼不觉”感觉,至今也没有人知道在其大爆发后会潜伏在何处。 目前已知第一次感染埃博拉的案例也是发生在1976年的苏丹和刚果民主共和国,且依据WHO,2014年西非的埃博拉大爆发是有史以来最大和最复杂的一次爆发。该病毒可通过被感染者的体液进行传播,且其不同类型产生的致死率也是不同的,比如Reston埃博拉甚至无法使人生病,而Bundibugyo埃博拉的致死率可达50%,sundan埃博拉的致死率已上升至71%。

NO.3狂犬病(Rabies virus)



狂犬病毒在电镜下有些类似“弹头”,而它靶向的目标就是人类的大脑。一旦该病毒入侵周围神经,可“劫持”了神经元细胞间传递细胞组分的“列车”,还会“操纵”它们直接驶入脊髓,进而便可以“乘坐”通往大脑的“列车”了。当病毒到达大脑后,会对大脑进行大规模的毁坏,使得人体出现恐水、狂犬病的症状。 在1920年左右推出的狂犬疫苗,很大程度降低了该病毒的致死率,而且已经让狂犬病在发达国家中变得极为罕见,但是狂犬病在印度和部分非洲地区仍是一个非常严重的问题。被感染的动物咬伤的人们如果没有注射疫苗,那么该病毒在潜伏一段时间后,可导致狂犬病的出现,死亡率达100%。

NO.4 人体免疫缺陷病毒(HIV)



顾名思义,这个病毒似乎生来就是免疫系统的“克星”。这种感染人类免疫系统细胞的慢病毒(Lentivirus),专门主攻人体的辅助T淋巴细胞系统,使得细胞免疫受损,进而可发展为持续性全身淋巴结肿大综合征,最后并发各种严重机会感染及机会肿瘤。而其一旦入侵机体细胞,就会和细胞整合一起,终生难以消除。 据估计,自从该病毒在80年代早期被发现后,全球有3600万人死于艾滋病。尽管强有力的抗病毒的药物可让感染的人们生活数年,但是在许多中低收入国家这种疾病的感染增长率可达95%。因而,这种病毒称为“潘多拉盒释放的魔鬼”,也成为了现代人类目前最为恐惧的疾病之一。

NO.5 天花病毒(Smallpox)



天花病毒是一种传染性极强的病毒,仅在20世纪,天花就已经杀死了3亿人。而幸存者身上无一例外会留下永久性的疤痕,且伴随着失明。没有人知道天花的具体治疗方法,唯一的防治方法是接种疫苗。因而在疫苗出现之前,人们一直都生活在被天花控制的恐惧之中。 而之所以将该病毒排在第五,是因为尽管其曾经造成了巨大的伤害,但是如今已经不足为惧了。可以说,消除天花是人类打的一场漂亮的战役。

NO.6 汉坦病毒(Hantavirus)



汉坦病毒心肺综合征(HPS)在1993年首发于美国,当时一个美国年轻人和他的未婚妻在HPS发病后短短几天死亡。几个月后,卫生部门从受感染人家里的鹿鼠身上分离出了汉坦病毒。 该病毒的传播途径并非人传人,而是感染自老鼠的排泄物。依据疾病控制与预防中心(CDC),美国每年有超过699人感染HPS,36%死于此疾病。且2010年的《临床微生物学综述》也指出,20世纪50年代早期曾爆发过一种不同的汉坦病毒,使得超过3000名士兵被感染,12%的人死于此病毒。

NO.7流感病毒(Influenza)



依据WHO统计,在流感爆发的典型季节,世界各地高达50万人将死于流感。1918年爆发的西班牙流感,在当时便感染世界40%的人口,造成大约5000万人死亡。 近年来,流感毒株开始呈现出多种类型,有时不同病毒遗传物质的重组,可产生更具危险性的病毒,使得疾病的传播将变的非常快,致死率也非常高。例如2009年猪流感大流行时,就导致了全球约20万人死亡。

NO.8 登革病毒(Dengue)



登革病毒于20世纪50年代首次在菲律宾和泰国被发现,自此后肆虐于全球的热带和亚热带地区。目前高达40%的世界人口居住在地区登革热流行区域,这种疾病(通过受感染的蚊子叮咬进行传播)很可能随着全球变暖而传播的更远。 依据WHO统计,每年该病毒会感染5千万至1亿人。虽然该病毒的死亡率(2.5%)低于其他病毒,但是该病毒会引起人类机体产生登革出血热,如果得不到及时治疗,死亡率会高达20%。而目前还没有登革热的疫苗,但是法国制药机构赛诺菲公司正在研发的一种实验性疫苗显示出了较好的临床结果。 

NO.9轮状病毒(Rotavirus)


轮状病毒(通过接触排泄物传播)最喜欢侵犯6个月~2岁免疫功能尚不成熟的宝宝,可使宝宝们产生急性肠炎和严重腹泻。据WHO统计,在全世界范围内,仅2008年就有45.3万5岁以下的儿童死于轮状病毒感染。

可目前已有两种疫苗可以保护儿童免受轮状病毒感染,因而很多国家在引进疫苗后,由这种病毒导致的住院率和死亡率已经在大幅度快速下降了。 

原始出处:

The 9 Deadliest Viruses on Earth. Jamaica Gleaner.July 20, 2016

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    2016-11-17 1e0f87b5m19(暂无匿称)

    害人的病毒

    0

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    2016-11-11 忠诚向上

    好好学习

    0

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    2016-11-09 李东泽

    这篇咨询不错哦,值得学习,对于临床工作和科研思路都很有帮助。

    0

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    2016-11-08 1df01bccm39(暂无匿称)

    病毒导致的死亡比战争多很多

    0

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    2016-11-08 大旺旺

    学习了啊

    0

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    2016-11-08 兰焱雨

    涨知识了……

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=156316, encodeId=b11e156316a1, content=害人的病毒, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161014/IMG5800221EE6BBB9541.jpg, createdBy=4beb1943458, createdName=1e0f87b5m19(暂无匿称), createdTime=Thu Nov 17 09:34:14 CST 2016, time=2016-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155098, encodeId=84f0155098d6, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Nov 11 20:04:56 CST 2016, time=2016-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154575, encodeId=9d001545e522, content=这篇咨询不错哦,值得学习,对于临床工作和科研思路都很有帮助。, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Wed Nov 09 13:57:42 CST 2016, time=2016-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154334, encodeId=d9c9154334eb, content=病毒导致的死亡比战争多很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM5rqTiaMSVSkFAupcTECOTdcVRmJQXbibJoicv5ibhcpa0vj5MGmac8wlPjuGnJISZGtOnC7rW0gbLuSE7iaEvAn0CC52ZhnRLdxtlQ/0, createdBy=1e291737907, createdName=1df01bccm39(暂无匿称), createdTime=Tue Nov 08 13:53:09 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154332, encodeId=d4bb1543326a, content=学习了啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Tue Nov 08 13:35:03 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154330, encodeId=49951543302e, content=涨知识了……, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/23/8c541a9831aec7026dffdf6bf34ab45d.jpg, createdBy=11371963624, createdName=兰焱雨, createdTime=Tue Nov 08 13:31:24 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154322, encodeId=68511543229b, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2dd71722896, createdName=studylzc, createdTime=Tue Nov 08 13:25:30 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154291, encodeId=ac2d15429174, content=谢谢小编分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Tue Nov 08 10:15:01 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154191, encodeId=cd4d15419102, content=太吓人,总结很到位, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/17/3872cad7a53dc9dcbd08202fb6313cf4.jpg, createdBy=2cb71609450, createdName=KO229256262, createdTime=Mon Nov 07 23:09:49 CST 2016, time=2016-11-07, status=1, ipAttribution=)]
    2016-11-08 studylzc

    谢谢分享!

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=156316, encodeId=b11e156316a1, content=害人的病毒, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161014/IMG5800221EE6BBB9541.jpg, createdBy=4beb1943458, createdName=1e0f87b5m19(暂无匿称), createdTime=Thu Nov 17 09:34:14 CST 2016, time=2016-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155098, encodeId=84f0155098d6, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Fri Nov 11 20:04:56 CST 2016, time=2016-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154575, encodeId=9d001545e522, content=这篇咨询不错哦,值得学习,对于临床工作和科研思路都很有帮助。, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Wed Nov 09 13:57:42 CST 2016, time=2016-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154334, encodeId=d9c9154334eb, content=病毒导致的死亡比战争多很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM5rqTiaMSVSkFAupcTECOTdcVRmJQXbibJoicv5ibhcpa0vj5MGmac8wlPjuGnJISZGtOnC7rW0gbLuSE7iaEvAn0CC52ZhnRLdxtlQ/0, createdBy=1e291737907, createdName=1df01bccm39(暂无匿称), createdTime=Tue Nov 08 13:53:09 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154332, encodeId=d4bb1543326a, content=学习了啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Tue Nov 08 13:35:03 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154330, encodeId=49951543302e, content=涨知识了……, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/23/8c541a9831aec7026dffdf6bf34ab45d.jpg, createdBy=11371963624, createdName=兰焱雨, createdTime=Tue Nov 08 13:31:24 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154322, encodeId=68511543229b, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2dd71722896, createdName=studylzc, createdTime=Tue Nov 08 13:25:30 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154291, encodeId=ac2d15429174, content=谢谢小编分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Tue Nov 08 10:15:01 CST 2016, time=2016-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154191, encodeId=cd4d15419102, content=太吓人,总结很到位, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/17/3872cad7a53dc9dcbd08202fb6313cf4.jpg, createdBy=2cb71609450, createdName=KO229256262, createdTime=Mon Nov 07 23:09:49 CST 2016, time=2016-11-07, status=1, ipAttribution=)]
    2016-11-08 明月清辉

    谢谢小编分享

    0

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    2016-11-07 KO229256262

    太吓人,总结很到位

    0

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