Baidu
map

宫缩药物诱发过度通气综合征一例

2018-06-04 李健 高德胜 阳兴 临床麻醉学杂志

产妇,33岁,身高155cm,体重56kg,因“G1P0孕34+2周,下腹痛1d余”入院。

【一般资料】

产妇,33岁,身高155cm,体重56kg

【主诉】

因“G1P0孕34+2周,下腹痛1d余”入院。

【体格检查】

体温36.7℃,HR98次/分,RR20次/分,BP118/74mmHg,ASAⅡ级,心肺未见明显异常。

【辅助检查】

术前血常规提示:Hb72g/L,Hct26%。

【初步诊断

(1)G1P0孕34+2周先兆早产;(2)双胎妊娠;(3)中度贫血。

【治疗】

拟于腰-硬联合麻醉下行子宫下段剖宫产术。产妇入室后于右侧臀部垫高约30°,常规心电监测:BP145/90mmHg,HR102次/分,RR20次/分,SpO296%,有间断宫缩痛。于L3~4间隙以针内针技术行腰-硬联合麻醉,穿刺过程顺利,腰麻用药为0.5%罗哌卡因2.8ml,向头侧置入硬膜外导管4cm,平卧位(稍左倾)下调整麻醉平面至T5。术中麻醉效果满意,给予补液及血管活性药物等措施维持循环稳定。于手术开始后第5、6分钟分别娩出一男婴及一女婴,新生儿Apgar评分分别为:1min8/9分,5min9/10分,10min10/10分。断脐后静脉输入抗生素,给予缩宫素20U宫体注射,然后以缩宫素20U加入500ml生理盐水中静滴维持。观察5min后发现子宫收缩欠佳,产科医师以卡前列素氨丁三醇250μg宫体注射,子宫收缩逐渐好转。给予上述药物约5min后,产妇诉胸闷、呼吸困难、有窒息感,并出现恶心、呕吐。此时BP100/55mmHg,HR118次/分,RR30次/分,SpO296%,心肺听诊无明显异常,双侧瞳孔等大,光反射灵敏,ECG未见明显ST-T改变。检查吸引瓶内出血约200ml,并再次确认感觉平面为T5,考虑原因为宫缩药物不良反应,给予面罩吸氧、适当升高血压(去氧肾上腺素)、镇静(咪达唑仑)、止吐(阿扎司琼)等治疗,症状无明显好转,产妇呼吸频率逐渐增快,最快达40次/分,约7min后产妇开始出现头痛、视物模糊、胸部麻木等症状。血气分析:pH7.48,PCO222.3mmHg,HCO-317.1mmol/L。提示原发性呼吸性碱中毒,嘱产妇放松,减慢呼吸频率,降低呼吸动度,采用可重复吸入面罩增加CO2重吸入,并持续泵注右美托咪定镇静,同时静脉滴注葡萄糖酸钙1g,预防呼吸性碱中毒导致的低钙血症。给予上述处理措施40min后停止镇静,产妇清醒后自觉症状明显好转。术后给予PCIA镇痛并送回产科重症监护室,并于监护室给予浓缩红细胞1U静脉输注。术后4h回访,产妇未述不适,最终诊断为过度通气综合征(hyperventilationsyndrome,HVS)。

原始出处:

李健, 高德胜, 阳兴,等. 宫缩药物诱发过度通气综合征一例[J]. 临床麻醉学杂志, 2017(2):206-207.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1743692, encodeId=f6c31e436921b, content=<a href='/topic/show?id=0cb1462e7c3' target=_blank style='color:#2F92EE;'>#宫缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46277, encryptionId=0cb1462e7c3, topicName=宫缩)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c34935182975, createdName=windight, createdTime=Mon Sep 10 07:41:00 CST 2018, time=2018-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431231, encodeId=853a143123181, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Jun 06 13:41:00 CST 2018, time=2018-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321522, encodeId=68a732152224, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Jun 05 00:13:17 CST 2018, time=2018-06-05, status=1, ipAttribution=)]
    2018-09-10 windight
  2. [GetPortalCommentsPageByObjectIdResponse(id=1743692, encodeId=f6c31e436921b, content=<a href='/topic/show?id=0cb1462e7c3' target=_blank style='color:#2F92EE;'>#宫缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46277, encryptionId=0cb1462e7c3, topicName=宫缩)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c34935182975, createdName=windight, createdTime=Mon Sep 10 07:41:00 CST 2018, time=2018-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431231, encodeId=853a143123181, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Jun 06 13:41:00 CST 2018, time=2018-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321522, encodeId=68a732152224, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Jun 05 00:13:17 CST 2018, time=2018-06-05, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1743692, encodeId=f6c31e436921b, content=<a href='/topic/show?id=0cb1462e7c3' target=_blank style='color:#2F92EE;'>#宫缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46277, encryptionId=0cb1462e7c3, topicName=宫缩)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c34935182975, createdName=windight, createdTime=Mon Sep 10 07:41:00 CST 2018, time=2018-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431231, encodeId=853a143123181, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Jun 06 13:41:00 CST 2018, time=2018-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321522, encodeId=68a732152224, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Jun 05 00:13:17 CST 2018, time=2018-06-05, status=1, ipAttribution=)]
    2018-06-05 飛歌

    学习了很有用

    0

Baidu
map
Baidu
map
Baidu
map