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Lancet:中低收入国家儿童腹泻负担及风险因素研究

2020-05-07 MedSci原创 MedSci原创

通过分析腹泻负担的地理空间趋势及其主要危险因素,研究人员可以评估国家各地区腹泻死亡风险因素,鉴于中低收入国家资源有限,准确地量化腹泻负担及其驱动因素对于精准的公共卫生十分重要

在低收入和中等收入国家中(LMICs),五岁以下儿童中有十分之一死于腹泻。国家间腹泻发病率和死亡率的差异很大,近日研究人员就腹泻负担最重国家的相关危险因素进行了考察。
 
研究人员使用了基于贝叶斯模型数据集,该数据集由94个LMICs的466研究组成,包含15072746名5岁以下儿童,结合2017年全球疾病、伤害和风险因素研究(GBD)的结果,估计2000年至2017年各国腹泻流行率、发病率和死亡率。根据这些数据,研究人员通过空间聚合绘制不同国家以下各级(称为单位)的腹泻负担,并通过创建聚合风险因子估计风险因素。
 
研究发现,腹泻死亡率下降幅度最大的地区是南亚、东南亚和南美洲,分别有54.0%、17.4%和59.5%的单位,腹泻死亡率下降幅度大于10%。尽管非洲大部分地区的儿童仍然面临较高的腹泻致死风险,但死亡人数最多的地区并非非洲,死亡率最高的单位在巴基斯坦。印度尼西亚的国内差异最为显著,部分地区的死亡率几乎是国家平均死亡率的四倍。死亡率的降低与水、卫生和个人卫生(WASH)的改善或儿童生长衰竭(CGF)的减少相关。同样,大多数高危地区的WASH较差、CGF高或口服补液治疗覆盖率低。
 
通过分析腹泻负担的地理空间趋势及其主要危险因素,研究人员可以评估国家各地区腹泻死亡风险因素,鉴于中低收入国家资源有限,准确地量化腹泻负担及其驱动因素对于精准的公共卫生十分重要。
 
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    2021-04-21 howi
  2. [GetPortalCommentsPageByObjectIdResponse(id=1830625, encodeId=83291830625ac, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 21 02:53:43 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813746, encodeId=d13a813e4637, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:06:47 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954003, encodeId=81721954003e4, content=<a href='/topic/show?id=1c6a262184c' target=_blank style='color:#2F92EE;'>#低收入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26218, encryptionId=1c6a262184c, topicName=低收入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Apr 04 01:53:43 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1642975, encodeId=d3a316429e5ce, content=<a href='/topic/show?id=f746213e822' target=_blank style='color:#2F92EE;'>#中低收入国家#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21378, encryptionId=f746213e822, topicName=中低收入国家)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35fb23047443, createdName=12499e01m54暂无昵称, createdTime=Fri Aug 28 19:53:43 CST 2020, time=2020-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033767, encodeId=f5031033e6716, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu May 07 21:53:43 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
    2020-08-27 14818eb4m67暂无昵称

    学习了

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1830625, encodeId=83291830625ac, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Apr 21 02:53:43 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813746, encodeId=d13a813e4637, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:06:47 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954003, encodeId=81721954003e4, content=<a href='/topic/show?id=1c6a262184c' target=_blank style='color:#2F92EE;'>#低收入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26218, encryptionId=1c6a262184c, topicName=低收入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sun Apr 04 01:53:43 CST 2021, time=2021-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1642975, encodeId=d3a316429e5ce, content=<a href='/topic/show?id=f746213e822' target=_blank style='color:#2F92EE;'>#中低收入国家#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=21378, encryptionId=f746213e822, topicName=中低收入国家)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35fb23047443, createdName=12499e01m54暂无昵称, createdTime=Fri Aug 28 19:53:43 CST 2020, time=2020-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033767, encodeId=f5031033e6716, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu May 07 21:53:43 CST 2020, time=2020-05-07, status=1, ipAttribution=)]
    2020-05-07 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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