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Arch Oral Biol:老年口腔微生物组的组成变化

2018-10-17 MedSci MedSci原创

衰老是一种可影响人体所有系统的生理过程。口腔中与年龄相关的变化反映了其微生物群的组成的变化,其可以与健康相容或形成有利于疾病建立的益生菌群落。本文重点讨论口腔微生物组的年龄驱动变化,以及其与常见口腔疾病的关系,包括龋齿、牙周炎、种植体周围炎和口腔念珠菌病。 本次回顾性研究结果显示,老年个体的口咽微生物可以繁殖一些微生物,如肠杆菌、假单胞菌、金黄色葡萄球菌和酵母,可以成为免疫力下降或整体健康状

衰老是一种可影响人体所有系统的生理过程。口腔中与年龄相关的变化反映了其微生物群的组成的变化,其可以与健康相容或形成有利于疾病建立的益生菌群落。本文重点讨论口腔微生物组的年龄驱动变化,以及其与常见口腔疾病的关系,包括龋齿、牙周炎、种植体周围炎和口腔念珠菌病。

本次回顾性研究结果显示,老年个体的口咽微生物可以繁殖一些微生物,如肠杆菌、假单胞菌、金黄色葡萄球菌和酵母,可以成为免疫力下降或整体健康状况恶化的老年人的机会性病原体。对于年轻人和老年人的常见口腔疾病,例如龋齿和牙周炎,没有发现相当大的微生物群变异,而老年人口腔放线菌的检出率增加。

综上所述,该研究结果表明,无论是天然存在还是由潜在疾病驱动,口腔生态都会随着时间的推移而动态改变,引起常驻口腔微生物组组成的变化。

原始出处:

Belibasakis GN. Microbiological changes of the ageing oral cavity. Arch Oral Biol. 2018 Oct 3;96:230-232. doi: 10.1016/j.archoralbio.2018.10.001.

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    2019-09-06 sunylz
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    2019-07-17 小几洁
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