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Sci Rep:儿童先天性风疹综合征的知觉缺失和发育延迟

2017-04-16 AlexYang MedSci原创

最近,研究人员就患有先天性风疹综合征(CRS)的儿童的发育障碍和知觉缺失进行了调查研究。2011年越南庆和省风疹大爆发后,研究人员在2011年9月到2013年五月间,共召集了41名患有CRS的儿童。到2013年11月,参与的调查的14名患者死亡,并有6名参与者丢失,研究人员对剩余的21名儿童患者进行了2013年到2015年的跟踪调查。研究人员发现,分别有13名和7名参与者有听力和眼科功能损失。另外

最近,研究人员就患有先天性风疹综合征(CRS)的儿童的发育障碍和知觉缺失进行了调查研究。2011年越南庆和省风疹大爆发后,研究人员在2011年9月到2013年五月间,共召集了41名患有CRS的儿童。到2013年11月,参与的调查的14名患者死亡,并有6名参与者丢失,研究人员对剩余的21名儿童患者进行了2013年到2015年的跟踪调查。

研究人员发现,分别有13名和7名参与者有听力和眼科功能损失。另外,研究人员发现,19(95%)的儿童,就是在2013年和/或者2015年中,至少在年龄和发展阶段问卷(ASQ)和/或者在丹佛智力发育筛查法第二版(Denver II)中至少有一个领域中有缺陷的,可能具有发育障碍的嫌疑。研究人员总能在ASQ交流区域(n=14 in 2013)和Denver II语言区域(n=13 in 2013)鉴定到发育障碍。另外,研究人员推测,在2013年的儿童自闭症修正清单中,7(41%)名参与者患有自闭症谱系障碍(ASD)。在2015年,研究人员发现,在问题解决失败方面(62%)和个人社交方面(62%)缺陷的儿童比例增加了,并且其中2名儿童通过第二版儿童自闭症评定量表测试被诊断为ASD。最后,研究人员指出,CRS儿童大多具有发育障碍,包括了自闭症并结合知觉功能异常。

原始出处:

Michiko Toizumi, Giang Thi Huong Nguyen, Hideki Motomura et al. Sensory defects and developmental delay among children with congenital rubella syndrome. Sci Rep. 13 April 2017. doi:10.1038/srep46483.

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    2017-04-26 往日如昨

    学习了谢谢分享

    0

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    2017-04-19 虈亣靌

    全程参与实验,即学即用,多次实践,确保掌握所学技术。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=190727, encodeId=788c190e27af, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Wed Apr 26 10:10:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=188777, encodeId=28ae188e771f, content=全程参与实验,即学即用,多次实践,确保掌握所学技术。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Apr 19 10:59:47 CST 2017, time=2017-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347157, encodeId=5830134e157f0, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Apr 18 03:13:00 CST 2017, time=2017-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369279, encodeId=c81913692e9af, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Tue Apr 18 03:13:00 CST 2017, time=2017-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430791, encodeId=03091430e917f, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Apr 18 03:13:00 CST 2017, time=2017-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626580, encodeId=9ad8162658076, content=<a href='/topic/show?id=b018100845a6' target=_blank style='color:#2F92EE;'>#风疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100845, encryptionId=b018100845a6, topicName=风疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bbed21043050, createdName=sunyl14, createdTime=Tue Apr 18 03:13:00 CST 2017, time=2017-04-18, status=1, ipAttribution=)]
    2017-04-18 neurowu
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    2017-04-18 huirong
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  6. [GetPortalCommentsPageByObjectIdResponse(id=190727, encodeId=788c190e27af, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Wed Apr 26 10:10:52 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=188777, encodeId=28ae188e771f, content=全程参与实验,即学即用,多次实践,确保掌握所学技术。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Apr 19 10:59:47 CST 2017, time=2017-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347157, encodeId=5830134e157f0, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Tue Apr 18 03:13:00 CST 2017, time=2017-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369279, encodeId=c81913692e9af, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Tue Apr 18 03:13:00 CST 2017, time=2017-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430791, encodeId=03091430e917f, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Apr 18 03:13:00 CST 2017, time=2017-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626580, encodeId=9ad8162658076, content=<a href='/topic/show?id=b018100845a6' target=_blank style='color:#2F92EE;'>#风疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100845, encryptionId=b018100845a6, topicName=风疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bbed21043050, createdName=sunyl14, createdTime=Tue Apr 18 03:13:00 CST 2017, time=2017-04-18, status=1, ipAttribution=)]
    2017-04-18 sunyl14
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