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Diabetes Care: 糖尿病控制可影响牙周病进展

2012-08-07 高晓方译 医学论坛网

     欧美学者的一项研究表明,糖尿病控制与后期牙缺失和牙周附着丧失加速进展相关,糖尿病类型则与之无关。论文于2012年7月30日在线发表于《糖尿病护理》(Diabetes Care)杂志。   此项研究中的健康受试者和2型糖尿病患者来自于德国SHIP研究(Pomerania健康研究),1型糖尿病受试者则来自于相关区域内的糖尿病诊所。共有2626例受试者(女性53%)被纳入研究。通

  牙周

  欧美学者的一项研究表明,糖尿病控制与后期牙缺失和牙周附着丧失加速进展相关,糖尿病类型则与之无关。论文于2012年7月30日在线发表于《糖尿病护理》(Diabetes Care)杂志。

  此项研究中的健康受试者和2型糖尿病患者来自于德国SHIP研究(Pomerania健康研究),1型糖尿病受试者则来自于相关区域内的糖尿病诊所。共有2626例受试者(女性53%)被纳入研究。通过医生诊断和/或HbA1c≥6.5%确定糖尿病。对糖尿病状况不知情的检查者实施每半月一次的牙周检查,并在基线和随访时评估牙周袋探测深度(PD)和牙周附着丧失(AL)。对平均PD改变(ΔMPD)、平均AL改变(ΔMAL)和偶发牙缺失数进行多变量回归分析。

  结果显示,在整体受试者中,ΔMPD和ΔMAL分别为(−0.08±0.5)mm和(0.08±1.03)mm;34%缺失1颗或以上牙齿。相对于无糖尿病受试者而言,伴有未控制2型糖尿病的受试者ΔMPD改变更为显著,伴有未控制1型或2型糖尿病的受试者ΔMAL则改变均更为显著(P<0.05)。未控制1型和2型糖尿病均与后期牙缺失风险升高相关(P<0.05)。

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