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Thyroid：维生素D与乳头状甲状腺癌的进展和预后

2016-02-18 Mechront 译 MedSci原创

乳头状甲状腺癌维生素D预后
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维生素D与多种癌症的进展和预后有关，研究者进行了一项研究，探究维生素D是否会对乳头状甲状腺癌(PTC)的进展和预后产生影响。该研究共纳入820名PTC患者，术前通过血液检测25 -羟维生素D水平。通过患者临床、病理和复发数据评估维生素D对预后的影响。根据术前维生素D水平将患者分为四组。研究数据显示，795 (97%)名患者表现出维生素D缺乏 (<30 ng/mL)。维生素D的水平与年龄、BM

维生素D与多种癌症的进展和预后有关，研究者进行了一项研究，探究维生素D是否会对乳头状甲状腺癌(PTC)的进展和预后产生影响。

该研究共纳入820名PTC患者，术前通过血液检测25 -羟维生素D水平。通过患者临床、病理和复发数据评估维生素D对预后的影响。根据术前维生素D水平将患者分为四组。

研究数据显示，795 (97%)名患者表现出维生素D缺乏 (<30 ng/mL)。维生素D的水平与年龄、BMI呈正相关，与促甲状腺素水平和抗甲状腺过氧化物酶抗体滴度呈负相关。校正年龄、性别、BMI、术前离子钙、甲状旁腺激素后，研究者没有发现维生素D与甲状腺外侵犯、淋巴结转移、晚期癌症（Ⅲ或Ⅳ）和复发风险间的联系。同样也没有发现维生素D与复发性或难治性PTC的关系。

研究结果表明，维生素D的水平不会对PTC患者疾病的进展或是预后产生影响。

原始出处：

Ahn HY, Chung YJ,et al.Serum 25-Hydroxyvitamin D Level Does Not Affect the Aggressiveness and Prognosis of Papillary Thyroid Cancer.Thyroid. 2016 Feb 9. [Epub ahead of print]

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    2016-03-28 wincls

    #乳头状甲状腺癌#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2040443, encodeId=45632040443de, content=<a href='/topic/show?id=e2f523589f3' target=_blank style='color:#2F92EE;'>#乳头状甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23589, encryptionId=e2f523589f3, topicName=乳头状甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=991e83, createdName=wincls, createdTime=Mon Mar 28 07:07:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044967, encodeId=278f204496e12, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Sat Jul 16 11:07:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74638, encodeId=1228e463820, content=VD的正常reference range是多少？, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Wed Mar 30 09:24:00 CST 2016, time=2016-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72489, encodeId=98d9e248927, content=阴性结果发文章不错不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=179, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a6a1604604, createdName=Gsurgeon, createdTime=Mon Mar 21 23:57:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-07-16 jianjun66

    #乳头状#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2040443, encodeId=45632040443de, content=<a href='/topic/show?id=e2f523589f3' target=_blank style='color:#2F92EE;'>#乳头状甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23589, encryptionId=e2f523589f3, topicName=乳头状甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=991e83, createdName=wincls, createdTime=Mon Mar 28 07:07:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044967, encodeId=278f204496e12, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Sat Jul 16 11:07:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74638, encodeId=1228e463820, content=VD的正常reference range是多少？, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Wed Mar 30 09:24:00 CST 2016, time=2016-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72489, encodeId=98d9e248927, content=阴性结果发文章不错不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=179, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a6a1604604, createdName=Gsurgeon, createdTime=Mon Mar 21 23:57:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-30 ssummer

    VD的正常reference range是多少？

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2040443, encodeId=45632040443de, content=<a href='/topic/show?id=e2f523589f3' target=_blank style='color:#2F92EE;'>#乳头状甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23589, encryptionId=e2f523589f3, topicName=乳头状甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=991e83, createdName=wincls, createdTime=Mon Mar 28 07:07:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044967, encodeId=278f204496e12, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Sat Jul 16 11:07:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74638, encodeId=1228e463820, content=VD的正常reference range是多少？, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Wed Mar 30 09:24:00 CST 2016, time=2016-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72489, encodeId=98d9e248927, content=阴性结果发文章不错不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=179, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a6a1604604, createdName=Gsurgeon, createdTime=Mon Mar 21 23:57:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-21 Gsurgeon

    阴性结果发文章不错不错

    0

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