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N Engl J Med:肥胖老年人减重 这个方法更有效

2017-06-23 吴星 环球医学

2017年5月,发表在《N Engl J Med》的一项由美国科学家进行的研究表明,减重联合有氧和抗阻运动是改善肥胖老年人功能状态的最有效方法。



2017年5月,发表在《N Engl J Med》的一项由美国科学家进行的研究表明,减重联合有氧和抗阻运动是改善肥胖老年人功能状态的最有效方法。

背景:肥胖导致老年人虚弱;但是,减重或加速年龄相关肌肉和骨骼质量减少,发生肌肉减少症和骨质减少。

方法:在这项涉及160例肥胖老人的临床试验中,研究人员评估了多种锻炼模式逆转虚弱和预防体重减少诱发的肌肉和骨骼质量降低的有效性。受试者被随机分配至体重管理项目联合3种锻炼项目的其中一种——有氧训练、抗阻训练或有氧训练联合抗阻训练联合,或对照组(无体重管理或运动项目)。主要结局为基线到6个月时,体能测试评分的变化(评分范围从0至36分;分数越高意味着表现越好)。次要结局包括其他虚弱测量、身体成分、骨密度和身体功能的变化。

结果:共有141例受试者完成本研究。联合组的体能测试评分增加高于有氧运动组和抗阻力组(分别为27.9~33.4分[增加21%] vs 29.3~33.2分[增加14%]和28.8~32.7分[增加14%];邦弗朗尼校正后P=0.01和P=0.02);所有运动组的评分增加高于对照组(组间比较P<0.001)。联合组和有氧运动组的峰值耗氧量(ml/体重kg/min)增长(分别为17.2~20.3[增加17%]和17.6~20.9[增加18%])高于抗阻训练组(17.0~18.3[增加8%])(两项比较P<0.001)。联合组和抗阻运动组的力量增加(分别为272~320 kg[增加18%]和288~337 kg[增加19%])高于有氧运动组(265~270 kg[增加4%])(两项比较P<0.001)。所有运动组的体重降低9%,但对照组无显着变化。联合组和抗阻训练组的瘦体重减少低于有氧运动组(分别为56.5~54.8 kg[降低3%]和58.1~57.1 kg[降低2%] vs 55.0~52.3 kg[降低5%]),全髋部位骨密度也是如此(g/cm2;分别为1.010~0.996[降低1%]和1.047~1.041[降低0.5%] vs 1.018~0.991[降低3%])(所有比较P<0.05)。运动相关不良事件包括肌肉骨骼损伤。

结论:在所测试的方法中,减重联合有氧和抗阻运动是改善肥胖老年人功能状态的最有效方法(国立卫生研究院提供资金;LITOE ClinicalTrials.gov编号,NCT01065636)。

原始出处:

Villareal DT, Aguirre L, Gurney AB, et al. Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults. N Engl J Med. 2017 May 18;376(20):1943-1955. doi: 10.1056/NEJMoa1616338.

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    2017-08-14 spoonycyy
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    2017-11-02 haouestc
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    2017-07-14 haige

    老年人体重控制应是减脂增肌。饮食与联合有氧、阻抗运动是最佳方案!

    0

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    2017-06-24 189****7206

    学习了谢谢分享

    0

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    2017-06-24 惠映实验室

    学习了,谢谢分享

    0

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    2017-06-23 lovetcm

    有氧+抗阻

    0

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    2017-06-23 flysky120

    老年人减肥,现在应该鼓励老人

    0

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