Baidu
map

Br J Dermatol:通过右手臂痣的数目可有效预测患黑色素瘤风险

2015-10-20 MedSci 译 MedSci原创

英国伦敦国王学院Simon Ribero领导的研究人员最近完成的一项研究表明,通过人们右手臂胎记和痣的数目可预测他们患黑色素瘤的风险。这项研究发表在Dermatology。 在美国,黑色素瘤在所有皮肤癌病例所占比例不到2%,但所导致的患者死亡率极高。今年,美国新发73000多名黑色素瘤患者,预计近1万名患者将死于黑色素瘤。 胎记或痣是导致民众患黑色素瘤的高危风险因素,若一个人的胎记或痣越多,则其患

英国伦敦国王学院Simon Ribero领导的研究人员最近完成的一项研究表明,通过人们右手臂胎记和痣的数目可预测他们患黑色素瘤的风险。这项研究发表在British Journal of Dermatology。 


在美国,黑色素瘤在所有皮肤癌病例所占比例不到2%,但所导致的患者死亡率极高。今年,美国新发73000多名黑色素瘤患者,预计近1万名患者将死于黑色素瘤。 

胎记或痣是导致民众患黑色素瘤的高危风险因素,若一个人的胎记或痣越多,则其患黑色素瘤的风险越大。

根据Ribero和他的同事们得出的结论,每个痣的存在表明民众患黑色素瘤的风险增加2-4%。但研究人员指出,依靠计数民众全身胎记或痣的数目估计其患黑色素瘤的风险无异于浪费时间和精力。因此,研究人员开始探究是否可以依靠身体某个部位的胎记总数估计个体全身胎记总数,因此同样可评估民众患患黑色素瘤的风险。 

1995年1月到2003年12月,研究人员对3594名白人双胞胎女性进行研究。经过培训的护士对参与者17个身体区域的痣的数目进行了统计。然后研究人员在另一项小规模研究中对400名男性和女性进行了同样的痣的数目统计。

研究人员发现,人们的右臂可有效预测个体身体的痣总数。若女性右臂的痣超过7个,则全身痣的总数超过50个的可能性超过90%;若女性右臂的痣超过11个,则她们全身的痣至少100个,表明她们患黑色素瘤的风险是常人的5倍。

Ribero博士认为,通过计数人们右手臂的痣的数目预计全身痣的数目,这种方法可有效估计人们患黑色素瘤的风险,并可及时有效做出防范措施和风险筛查。 

Ribero S, Zugna D, Osella-Abate S, Glass D, Nathan P, Spector T, Bataille V.Prediction of high naevus count in a healthy uk population to estimate melanoma risk.Br J Dermatol. 2015 Oct 19. 


版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=49642, encodeId=393c4964261, content=很值得好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=187, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 20:46:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1680310, encodeId=ce701680310af, content=<a href='/topic/show?id=9e5c86e0712' target=_blank style='color:#2F92EE;'>#色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86707, encryptionId=9e5c86e0712, topicName=色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=343027846633, createdName=sunylz, createdTime=Sun Mar 20 18:41:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487612, encodeId=752c148e6128c, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1558725, encodeId=18ad1558e25bb, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1564734, encodeId=fa761564e3482, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]
    2015-12-27 忠诚向上

    很值得好学习

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=49642, encodeId=393c4964261, content=很值得好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=187, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 20:46:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1680310, encodeId=ce701680310af, content=<a href='/topic/show?id=9e5c86e0712' target=_blank style='color:#2F92EE;'>#色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86707, encryptionId=9e5c86e0712, topicName=色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=343027846633, createdName=sunylz, createdTime=Sun Mar 20 18:41:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487612, encodeId=752c148e6128c, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1558725, encodeId=18ad1558e25bb, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1564734, encodeId=fa761564e3482, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]
    2016-03-20 sunylz
  3. [GetPortalCommentsPageByObjectIdResponse(id=49642, encodeId=393c4964261, content=很值得好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=187, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 20:46:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1680310, encodeId=ce701680310af, content=<a href='/topic/show?id=9e5c86e0712' target=_blank style='color:#2F92EE;'>#色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86707, encryptionId=9e5c86e0712, topicName=色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=343027846633, createdName=sunylz, createdTime=Sun Mar 20 18:41:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487612, encodeId=752c148e6128c, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1558725, encodeId=18ad1558e25bb, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1564734, encodeId=fa761564e3482, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]
    2015-10-22 yese
  4. [GetPortalCommentsPageByObjectIdResponse(id=49642, encodeId=393c4964261, content=很值得好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=187, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 20:46:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1680310, encodeId=ce701680310af, content=<a href='/topic/show?id=9e5c86e0712' target=_blank style='color:#2F92EE;'>#色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86707, encryptionId=9e5c86e0712, topicName=色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=343027846633, createdName=sunylz, createdTime=Sun Mar 20 18:41:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487612, encodeId=752c148e6128c, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1558725, encodeId=18ad1558e25bb, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1564734, encodeId=fa761564e3482, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=49642, encodeId=393c4964261, content=很值得好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=187, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Dec 27 20:46:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1680310, encodeId=ce701680310af, content=<a href='/topic/show?id=9e5c86e0712' target=_blank style='color:#2F92EE;'>#色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86707, encryptionId=9e5c86e0712, topicName=色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=343027846633, createdName=sunylz, createdTime=Sun Mar 20 18:41:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487612, encodeId=752c148e6128c, content=<a href='/topic/show?id=ae23e118228' target=_blank style='color:#2F92EE;'>#痣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71182, encryptionId=ae23e118228, topicName=痣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21678344192, createdName=yese, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1558725, encodeId=18ad1558e25bb, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1564734, encodeId=fa761564e3482, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Thu Oct 22 13:41:00 CST 2015, time=2015-10-22, status=1, ipAttribution=)]

相关资讯

NEJM:髓状皮脂腺痣病例报道

一名12岁的女孩在其头皮表面出现了一块7.0cmX4.0cm大小的黄褐色的斑块。据该女孩主诉,这斑块自其出生以来一直存在,并随年龄的增长不断增大(如图A所示)。在体格检查,神经系统检查,以及颅骨X线检查均未见明显异常。但取样做组织学病理学检查,结果显示乳头瘤样表皮增生和大量成熟的皮脂腺,可幸的是没有出现癌变的迹象(如图B组所示)。根据该女孩所出现的临床症状和检查结果,最后医生诊断其患上的是髓状皮脂

NEJM:黑头粉刺样痣

一名19岁的男子称在其左侧锁骨区域出现先天性的皮肤病变(如图A所示),视诊可见扩张毛囊皮脂腺开口与角质栓紧密排列,类似于经典粉刺(如图B)。这些皮脂腺开口均沿左锁骨呈线性分布和延伸到背上,形成了巧妙的色素沉着带,但没有明显的界限。经体格检查,该男子没有出现相关的神经系统异常或骨骼畸形的现象。取皮肤活组织病理学检查,可见典型的、分组的和扩张毛囊口充满角蛋白,但未见头发轴。根据该男子的临床症状及检查结

从痣到黑色素瘤的距离有多远?

黑色素瘤 起源于黑色素细胞;发生于皮肤和黏膜;进展快,死亡率高;人种差异明显 黑色素瘤的“ABCDE” Asymmetry 不对称性 Border 边缘 Color 颜色 Diameter 直径 Evolving 进展  “丑小鸭理论” 该痣在同一个体中观察越来越像彼此,而MM经常偏离本痣图案。这种临床实现指向不仅评估病变有关的形态,但也比较来周围病变,寻找

皮肤有痣?警惕患黑色素瘤风险!

黑色素瘤是皮肤癌中最常见的,但最严重的类型。根据墨尔本大学、牛津大学和Epworth HealthCare专家公布的一项研究证实:假如你皮肤有痣,患黑色素瘤的风险会翻两番。 研究人员比较两组人的医疗记录,其中一组271656人在因任何疾病而进行医院访问时被记录有痣,另一组10130417人没有痣记录。两组比较发现,相比没有记录痣的一组,有痣记录的一组更容易患黑素瘤,风险增加约4.

PLoS Med:多痣女孩儿可能会增加乳腺癌发病风险

近日刊登在PLOS Medicine上的两篇研究报告指出,女性痣数量(皮肤色素痣)可能与乳腺癌发病风险相关。 但是该研究没有得出确切结论证明女性皮肤色素痣数量增多会增加乳腺癌发病风险,而实际上研究人员仅仅解释了两者之间可能存在的激素及基因关联。 其中一篇研究的主要作者,隶属于国家健康与医学研究院的Kvaskoff表示,“这不会成为女性新的困扰,我认为多痣与乳腺癌并没有直接的因果关系。” 研究

NEJM:治疗贝克尔痣---爱美之心,人皆有之!

近日,一位15岁的健康小男孩来到皮肤科门诊就诊,对主治医生展现他胸前的一大片色素沉着的区域。据该小男孩反应,他自幼时胸前就有那么一片的色素沉着现象。到了青春期的时候,这种现象更为严重,随后慢慢地开始发展为长出黑色的头发。而经过询问,他的家族里并没有其他的亲属出现过类似的症状。 通过体格检查发现,那些边界清楚的棕褐色斑点附近覆盖着深色的黑毛,这些黑毛覆盖了整个上胸部、右

Baidu
map
Baidu
map
Baidu
map