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现有的抗疟药物可用于治疗癌症

2017-11-24 MedSci MedSci原创

根据一项新的临床研究,抗疟药物氯喹和羟基氯喹可作为一种新的癌症治疗方法。来自抗癌基金(ReDO)项目的研究人员称,这些药物还在进一步的临床研究中,这是一项比利时和以美国为基础的全球国际合作。作者对氯喹和羟氯喹的潜力尤其感到兴奋,因为有证据表明,它们使肿瘤细胞对癌症治疗更加敏感。该研究的第一作者比利时鲁汶大学的Ciska Verbaanderd说:"氯喹和羟氯喹的有趣之处在于其多重作用机制。这些抗疟


根据一项新的临床研究,抗疟药物氯喹和羟基氯喹可作为一种新的癌症治疗方法。
来自抗癌基金(ReDO)项目的研究人员称,这些药物还在进一步的临床研究中,这是一项比利时和以美国为基础的全球国际合作。

作者对氯喹和羟氯喹的潜力尤其感到兴奋,因为有证据表明,它们使肿瘤细胞对癌症治疗更加敏感。

该研究的第一作者比利时鲁汶大学的Ciska Verbaanderd说:"氯喹和羟氯喹的有趣之处在于其多重作用机制。这些抗疟药物对癌细胞和肿瘤微环境都起作用。对这一点的研究在肿瘤生物学中引起了有趣的科学见解,如自噬、肿瘤血管免疫系统的重要性。

"研究结果使我们相信,这些抗疟药物能为某些癌症患者提供重要的临床益处,特别是与标准的抗癌治疗相结合。这应该通过更多的临床结果来证实。"

"全球治疗"的联合创始人、该评论的作者之一Vikas p . Sukhatme博士补充道: "我们期待30多个使用氯喹或羟氯喹进行癌症治疗的临床研究的结果。"

研究人员希望,随着这项研究的发表,越来越多的人意识到潜在的应用将会把这些药物从药箱里取出,并投入到癌症治疗中。

ReDO项目的以前的文章探讨了如何将廉价的常用药物如β受体阻滞剂和抗真菌药物"重新利用"并用作癌症治疗的一部分。

这项研究已经发表在ecancermedicalscience。


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  2. [GetPortalCommentsPageByObjectIdResponse(id=1951547, encodeId=6b3a195154ee9, content=<a href='/topic/show?id=aeeb5545681' target=_blank style='color:#2F92EE;'>#抗疟药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55456, encryptionId=aeeb5545681, topicName=抗疟药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Fri Dec 08 03:00:00 CST 2017, time=2017-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264139, encodeId=b767264139a2, content=厉害了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/qwgBOb0jiboVc8S5jZFrOc8MHsRbo5FQUvJFxpO6usINcsibP3I0apzqDGGICzsDuvQjDPXB3OloAf7ZYfukWricg/0, createdBy=17702189176, createdName=程岗, createdTime=Sat Nov 25 09:00:00 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264053, encodeId=315d2640535e, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Nov 25 00:17:48 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264052, encodeId=34e726405203, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Nov 25 00:17:08 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264043, encodeId=4ee426404396, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Nov 25 00:08:41 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264020, encodeId=b7bf26402018, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Fri Nov 24 22:53:23 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264019, encodeId=834a264019c9, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Fri Nov 24 22:33:51 CST 2017, time=2017-11-24, status=1, ipAttribution=)]
    2017-11-25 程岗

    厉害了

    0

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    2017-11-25 明天会更好!

    学习了.谢谢分享.

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1951547, encodeId=6b3a195154ee9, content=<a href='/topic/show?id=aeeb5545681' target=_blank style='color:#2F92EE;'>#抗疟药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55456, encryptionId=aeeb5545681, topicName=抗疟药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Fri Dec 08 03:00:00 CST 2017, time=2017-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264139, encodeId=b767264139a2, content=厉害了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/qwgBOb0jiboVc8S5jZFrOc8MHsRbo5FQUvJFxpO6usINcsibP3I0apzqDGGICzsDuvQjDPXB3OloAf7ZYfukWricg/0, createdBy=17702189176, createdName=程岗, createdTime=Sat Nov 25 09:00:00 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264053, encodeId=315d2640535e, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Nov 25 00:17:48 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264052, encodeId=34e726405203, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Nov 25 00:17:08 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264043, encodeId=4ee426404396, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Nov 25 00:08:41 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264020, encodeId=b7bf26402018, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Fri Nov 24 22:53:23 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264019, encodeId=834a264019c9, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Fri Nov 24 22:33:51 CST 2017, time=2017-11-24, status=1, ipAttribution=)]
    2017-11-25 明天会更好!

    学习了.谢谢分享.

    0

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    2017-11-25 飛歌

    厉害了我的哥

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1951547, encodeId=6b3a195154ee9, content=<a href='/topic/show?id=aeeb5545681' target=_blank style='color:#2F92EE;'>#抗疟药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55456, encryptionId=aeeb5545681, topicName=抗疟药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Fri Dec 08 03:00:00 CST 2017, time=2017-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264139, encodeId=b767264139a2, content=厉害了, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/qwgBOb0jiboVc8S5jZFrOc8MHsRbo5FQUvJFxpO6usINcsibP3I0apzqDGGICzsDuvQjDPXB3OloAf7ZYfukWricg/0, createdBy=17702189176, createdName=程岗, createdTime=Sat Nov 25 09:00:00 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264053, encodeId=315d2640535e, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Nov 25 00:17:48 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264052, encodeId=34e726405203, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Nov 25 00:17:08 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264043, encodeId=4ee426404396, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Nov 25 00:08:41 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264020, encodeId=b7bf26402018, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Fri Nov 24 22:53:23 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264019, encodeId=834a264019c9, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Fri Nov 24 22:33:51 CST 2017, time=2017-11-24, status=1, ipAttribution=)]
    2017-11-24 131****2916

    不错的文章值得推荐

    0

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    2017-11-24 131****2916

    不错的文章值得推荐

    0

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