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Eur Heart J:睡眠和打盹时间,与心血管事件及死亡率的关联

2018-12-05 xing.T MedSci原创

由此可见,每天6-8小时的总睡眠时间与死亡和主要心血管事件的风险最低相关。白天午睡与夜间睡眠时间超过6小时的个体发生主要心血管事件和死亡风险增加,但在睡眠时间≤6小时/晚的个体中则没有。

近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,该研究旨在调查估计的每日总睡眠持续时间和白天睡眠持续时间与死亡和主要血管事件之间的关联。

研究人员根据床上睡觉时间和自我报告的午睡时间估算了每日睡眠和白天小睡的持续时间,并评估了它们与来自七个地区的116632名参与者死亡和主要心血管事件的综合结局之间的关联。

中位随访7.8年后,研究人员记录了4381例死亡和4365例主要心血管事件患者。结果显示,较短(≤6小时/天)和较长(>8小时/天)的总睡眠持续时间与年龄和性别调整后的复合结局风险增加相关。在调整人口统计特征、生活方式行为和健康状况后,观察到它们之间的J形关联。与睡眠时间为6-8小时/天的参与者相比,那些睡眠时间≤6小时/天的患者复合结局风险增加的并不显著[风险比(HR)为1.09; 95%置信区间为0.99-1.20]。随着估计的睡眠持续时间增加,研究人员也注意到复合结局风险增加具有显著趋势[持续8-9小时/天的HR为1.05(0.99-1.12),8-9小时/天的HR为1.17(1.09-1.25)以及超过10小时/天的HR为1.41(1.30-1.53),趋势P<0.0001]。每种全因死亡和主要心血管事件的结果相似。夜间睡眠持续时间超过6小时的参与者中白天午睡时间与复合事件风险增加相关,而在夜间睡眠时间较短(≤6小时)的参与者中则不然。

由此可见,每天6-8小时的总睡眠时间的个体死亡和主要心血管事件的风险最低。白天午睡与夜间睡眠时间超过6小时的个体发生主要心血管事件和死亡风险增加相关,但在睡眠时间≤6小时/晚的个体中则不存在这种相关性。

原始出处:

Chuangshi Wang.et al. Association of estimated sleep duration and naps with mortality and cardiovascular events: a study of 116 632 people from 21 countries. Eur Heart J.2018. https://doi.org/10.1093/eurheartj/ehy695

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    2018-12-07 zhaojie88
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    2018-12-07 slcumt
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    2018-12-05 医者仁心5538

    学习了

    0

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    2018-12-05 Keithen

    excuseme?moresleep,moredanger???

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1643584, encodeId=442d16435843a, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Tue Oct 29 19:02:00 CST 2019, time=2019-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357015, encodeId=4c84135e0158d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Dec 07 09:02:00 CST 2018, time=2018-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563014, encodeId=117f15630144d, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Dec 07 09:02:00 CST 2018, time=2018-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354563, encodeId=98ff35456324, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Wed Dec 05 22:05:10 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354559, encodeId=d88c3545590e, content=excuseme?moresleep,moredanger???, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/07/26/809de36ba5fee78135ed9fe0fe2607f7.jpg, createdBy=22ef2409559, createdName=Keithen, createdTime=Wed Dec 05 21:54:10 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354556, encodeId=500635455650, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Wed Dec 05 21:29:40 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354544, encodeId=668635454412, content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Wed Dec 05 19:52:03 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354542, encodeId=1d2e3545424b, content=我没有理解错的话,午睡或者晚上睡得多反而心血管和死亡风险会增加?, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/12/05/a4e7254ac63874f1a62a80716f968276.jpg, createdBy=60942210209, createdName=阳台小小酥, createdTime=Wed Dec 05 19:44:20 CST 2018, time=2018-12-05, status=1, ipAttribution=)]
    2018-12-05 天地飞扬

    了解一下,谢谢分享!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1643584, encodeId=442d16435843a, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Tue Oct 29 19:02:00 CST 2019, time=2019-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357015, encodeId=4c84135e0158d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Dec 07 09:02:00 CST 2018, time=2018-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563014, encodeId=117f15630144d, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Dec 07 09:02:00 CST 2018, time=2018-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354563, encodeId=98ff35456324, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Wed Dec 05 22:05:10 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354559, encodeId=d88c3545590e, content=excuseme?moresleep,moredanger???, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/07/26/809de36ba5fee78135ed9fe0fe2607f7.jpg, createdBy=22ef2409559, createdName=Keithen, createdTime=Wed Dec 05 21:54:10 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354556, encodeId=500635455650, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Wed Dec 05 21:29:40 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354544, encodeId=668635454412, content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Wed Dec 05 19:52:03 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354542, encodeId=1d2e3545424b, content=我没有理解错的话,午睡或者晚上睡得多反而心血管和死亡风险会增加?, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/12/05/a4e7254ac63874f1a62a80716f968276.jpg, createdBy=60942210209, createdName=阳台小小酥, createdTime=Wed Dec 05 19:44:20 CST 2018, time=2018-12-05, status=1, ipAttribution=)]
    2018-12-05 lietome15

    好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1643584, encodeId=442d16435843a, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Tue Oct 29 19:02:00 CST 2019, time=2019-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357015, encodeId=4c84135e0158d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Dec 07 09:02:00 CST 2018, time=2018-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563014, encodeId=117f15630144d, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Dec 07 09:02:00 CST 2018, time=2018-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354563, encodeId=98ff35456324, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Wed Dec 05 22:05:10 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354559, encodeId=d88c3545590e, content=excuseme?moresleep,moredanger???, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/07/26/809de36ba5fee78135ed9fe0fe2607f7.jpg, createdBy=22ef2409559, createdName=Keithen, createdTime=Wed Dec 05 21:54:10 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354556, encodeId=500635455650, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Wed Dec 05 21:29:40 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354544, encodeId=668635454412, content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Wed Dec 05 19:52:03 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=354542, encodeId=1d2e3545424b, content=我没有理解错的话,午睡或者晚上睡得多反而心血管和死亡风险会增加?, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/12/05/a4e7254ac63874f1a62a80716f968276.jpg, createdBy=60942210209, createdName=阳台小小酥, createdTime=Wed Dec 05 19:44:20 CST 2018, time=2018-12-05, status=1, ipAttribution=)]
    2018-12-05 阳台小小酥

    我没有理解错的话,午睡或者晚上睡得多反而心血管和死亡风险会增加?

    0

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