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Open Med： 吸烟对骨折愈合的影响

2018-09-30 MedSci MedSci原创

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尽管机体有再生和重吸收的骨能力，但是干扰或延迟愈合仍然是最严重的骨折相关并发症之一。尽管目前在理解和治疗骨折方面取得了相当大的进展。本研究旨在评估患有创伤后假关节的患者（吸烟者和非吸烟者）的治疗结果。研究纳入因多发性骨折导致的创伤后假关节病患者。研究组和对照组进一步细分为：非吸烟者，戒烟后2年以上的非吸烟者和吸烟者。对男性和女性进行了独立测试。除了其他治疗方法外，研究组接受浓缩PRP（富含血小板的

尽管机体有再生和重吸收的骨能力，但是干扰或延迟愈合仍然是最严重的骨折相关并发症之一。尽管目前在理解和治疗骨折方面取得了相当大的进展。本研究旨在评估患有创伤后假关节的患者（吸烟者和非吸烟者）的治疗结果。

研究纳入因多发性骨折导致的创伤后假关节病患者。研究组和对照组进一步细分为：非吸烟者，戒烟后2年以上的非吸烟者和吸烟者。对男性和女性进行了独立测试。除了其他治疗方法外，研究组接受浓缩PRP（富含血小板的血浆）以帮助骨愈合过程，或者通过随访时的放射学评估确认延迟愈合的情况。

结果显示，戒烟后非吸烟者和非吸烟者> 2年的骨折愈合平均时间为8周，而在吸烟者中，愈合过程显著延长（男性和女性均为18周）。

综上所述，该研究结果表明，与吸烟者相比，非吸烟者的感染风险较小，骨骼炎症和延迟愈合的风险较高。

原始出处：

Michał Wechmann, Paweł Ziętek, et al., The Effect of Smoking on Posttraumatic Pseudoarthrosis Healing after Internal Stabilization, Treated with Platelet Rich Plasma (PRP). Open Med (Wars). 2018; 13: 425–432.

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    2019-03-14 feather89

    #PE#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1727633, encodeId=76bf1e27633ff, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Mar 14 08:41:00 CST 2019, time=2019-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689122, encodeId=5763168912221, content=<a href='/topic/show?id=b8ac10168e8b' target=_blank style='color:#2F92EE;'>#骨折愈合#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101687, encryptionId=b8ac10168e8b, topicName=骨折愈合)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce4c28733108, createdName=HinsMax, createdTime=Fri Feb 22 19:41:00 CST 2019, time=2019-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609151, encodeId=8cd21609151ac, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Oct 02 12:41:00 CST 2018, time=2018-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347437, encodeId=a6a234e43782, content=了解一下，谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Sep 30 21:59:18 CST 2018, time=2018-09-30, status=1, ipAttribution=)]
    2019-02-22 HinsMax

    #骨折愈合#

    0

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    2018-10-02 ms3994565386320060

    #Med#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1727633, encodeId=76bf1e27633ff, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Mar 14 08:41:00 CST 2019, time=2019-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1689122, encodeId=5763168912221, content=<a href='/topic/show?id=b8ac10168e8b' target=_blank style='color:#2F92EE;'>#骨折愈合#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101687, encryptionId=b8ac10168e8b, topicName=骨折愈合)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce4c28733108, createdName=HinsMax, createdTime=Fri Feb 22 19:41:00 CST 2019, time=2019-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609151, encodeId=8cd21609151ac, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Oct 02 12:41:00 CST 2018, time=2018-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347437, encodeId=a6a234e43782, content=了解一下，谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Sep 30 21:59:18 CST 2018, time=2018-09-30, status=1, ipAttribution=)]
    2018-09-30 天地飞扬

    了解一下，谢谢分享！

    0

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