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Mayo Clin Proc:美国老年人带状疱疹发生后,心肌梗死和卒中发生风险增加

2016-01-23 MedSci译 MedSci原创

目的:旨在评估美国社区老年人群中带状疱疹后,卒中和心肌梗死(MI)发生的风险。病人和方法:研究者进行了一项社区队列研究(1986年1月1日至2011年10月1日)比较明尼苏达奥姆斯特德县50岁及以上的有无带状疱疹的居民,和按照性别和年龄相匹配的无带状疱疹史的受试者卒中和MI发生的风险。指标性带状疱疹后3、6、12、36个月后加为长期风险的危险比(长达28.6年)来表示心肌梗死和中风的OR值。结果:

目的:旨在评估美国社区老年人群中带状疱疹后,卒中心肌梗死(MI)发生的风险。

病人和方法:研究者进行了一项社区队列研究(1986年1月1日至2011年10月1日)比较明尼苏达奥姆斯特德县50岁及以上的有无带状疱疹的居民,和按照性别和年龄相匹配的无带状疱疹史的受试者卒中和MI发生的风险。指标性带状疱疹后3、6、12、36个月后加为长期风险的危险比(长达28.6年)来表示心肌梗死和中风的OR值。

结果:带状疱疹的患者发生MI和卒中的风险和混杂因素较多,表明,他们的健康状态不良。控制多种危险因素时,与未发生带状疱疹的患者相比,带状疱疹发生3个月后,卒中发生的风险增加(OR:0.53;95% CI,1.10-2.33)。带状疱疹和3个月后MI的相关性不是稳固的。带状疱疹与3个月之外的任何时间点卒中和MI发生风险增加不相关。

结论:带状疱疹仅短期发生中风风险增加有关,如果预防带状疱疹的发生,可预防卒中的发生。

原文出处:

Yawn BP, Wollan PC, et al. Risk of Stroke and Myocardial Infarction After Herpes Zoster in Older Adults in a US Community Population. Mayo Clin Proc. 2016 Jan.

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    2016-08-04 linlin2312
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    2016-01-27 李继凯

    受教

    0

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    2016-01-25 sunylz
  5. [GetPortalCommentsPageByObjectIdResponse(id=1976895, encodeId=324619e689524, content=<a href='/topic/show?id=b9f11560065' target=_blank style='color:#2F92EE;'>#ROC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15600, encryptionId=b9f11560065, topicName=ROC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Thu Aug 04 11:33:00 CST 2016, time=2016-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61584, encodeId=f09661584ab, content=受教, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 23:44:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580361, encodeId=fbff15803619e, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Mon Jan 25 08:33:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601788, encodeId=674c1601e885d, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Mon Jan 25 08:33:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59011, encodeId=21aa5901188, content=病毒性心肌炎,或说明人体的抵抗力差, beContent=null, objectType=article, channel=null, level=null, likeNumber=192, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Sun Jan 24 17:55:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58968, encodeId=922e589686b, content=这两种疾病看似毫不关联,但是也可能存在某些潜在的有可能相关的这些因素,这个研究非常值得启发, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sun Jan 24 12:00:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58944, encodeId=3d57589449b, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Sun Jan 24 01:18:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58929, encodeId=bf0d5892923, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jan 23 22:35:00 CST 2016, time=2016-01-23, status=1, ipAttribution=)]
    2016-01-24 1de3b290m83(暂无匿称)

    病毒性心肌炎,或说明人体的抵抗力差

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1976895, encodeId=324619e689524, content=<a href='/topic/show?id=b9f11560065' target=_blank style='color:#2F92EE;'>#ROC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15600, encryptionId=b9f11560065, topicName=ROC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Thu Aug 04 11:33:00 CST 2016, time=2016-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61584, encodeId=f09661584ab, content=受教, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 23:44:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580361, encodeId=fbff15803619e, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Mon Jan 25 08:33:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601788, encodeId=674c1601e885d, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Mon Jan 25 08:33:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59011, encodeId=21aa5901188, content=病毒性心肌炎,或说明人体的抵抗力差, beContent=null, objectType=article, channel=null, level=null, likeNumber=192, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Sun Jan 24 17:55:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58968, encodeId=922e589686b, content=这两种疾病看似毫不关联,但是也可能存在某些潜在的有可能相关的这些因素,这个研究非常值得启发, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sun Jan 24 12:00:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58944, encodeId=3d57589449b, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Sun Jan 24 01:18:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58929, encodeId=bf0d5892923, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jan 23 22:35:00 CST 2016, time=2016-01-23, status=1, ipAttribution=)]
    2016-01-24 medcardio

    这两种疾病看似毫不关联,但是也可能存在某些潜在的有可能相关的这些因素,这个研究非常值得启发

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1976895, encodeId=324619e689524, content=<a href='/topic/show?id=b9f11560065' target=_blank style='color:#2F92EE;'>#ROC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15600, encryptionId=b9f11560065, topicName=ROC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Thu Aug 04 11:33:00 CST 2016, time=2016-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61584, encodeId=f09661584ab, content=受教, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 23:44:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580361, encodeId=fbff15803619e, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Mon Jan 25 08:33:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601788, encodeId=674c1601e885d, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Mon Jan 25 08:33:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59011, encodeId=21aa5901188, content=病毒性心肌炎,或说明人体的抵抗力差, beContent=null, objectType=article, channel=null, level=null, likeNumber=192, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Sun Jan 24 17:55:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58968, encodeId=922e589686b, content=这两种疾病看似毫不关联,但是也可能存在某些潜在的有可能相关的这些因素,这个研究非常值得启发, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sun Jan 24 12:00:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58944, encodeId=3d57589449b, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Sun Jan 24 01:18:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58929, encodeId=bf0d5892923, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jan 23 22:35:00 CST 2016, time=2016-01-23, status=1, ipAttribution=)]
    2016-01-24 zhuzhuba1

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1976895, encodeId=324619e689524, content=<a href='/topic/show?id=b9f11560065' target=_blank style='color:#2F92EE;'>#ROC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15600, encryptionId=b9f11560065, topicName=ROC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Thu Aug 04 11:33:00 CST 2016, time=2016-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61584, encodeId=f09661584ab, content=受教, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Wed Jan 27 23:44:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580361, encodeId=fbff15803619e, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Mon Jan 25 08:33:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601788, encodeId=674c1601e885d, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Mon Jan 25 08:33:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59011, encodeId=21aa5901188, content=病毒性心肌炎,或说明人体的抵抗力差, beContent=null, objectType=article, channel=null, level=null, likeNumber=192, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Sun Jan 24 17:55:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58968, encodeId=922e589686b, content=这两种疾病看似毫不关联,但是也可能存在某些潜在的有可能相关的这些因素,这个研究非常值得启发, beContent=null, objectType=article, channel=null, level=null, likeNumber=156, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sun Jan 24 12:00:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58944, encodeId=3d57589449b, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Sun Jan 24 01:18:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=58929, encodeId=bf0d5892923, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=194, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Sat Jan 23 22:35:00 CST 2016, time=2016-01-23, status=1, ipAttribution=)]
    2016-01-23 dhzzm

    值得学习

    0

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研究者进行了一项研究,探究治疗心血管疾病包括高血压等相关药物,是否会增加>65岁人群脆性骨折风险。该回顾性队列研究纳入了1 586 554名年龄>65岁的参与者。通过处方获取参与者心血管疾病相关药物(硝酸盐、地高辛、噻嗪类、呋塞米、血管紧张素转换酶抑制剂、血管紧张素受体拮抗剂、β受体阻滞剂、钙拮抗剂和他汀类药物)暴露情况,使用多因素泊松回归模型评估药物与脆性骨折风险间关系,以及校正后IRRs。研究

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亚临床甲状腺功能减退症和甲状腺功能亢进症与老年人死亡率之间的关系是不明确的。研究者进行了一项研究,探讨亚临床甲减和亚临床甲亢与老年人死亡率间的关系。该回顾性队列研究纳入了65岁以上人群,排除掉已知甲状腺疾病或甲状腺药物治疗的参与者。基于TSH值将参与者分为3组:正常组、亚临床甲减组(TSH > 4.2 mIU/L)、亚临床甲亢组(TSH <0.35 mIU/L)。最终该研究纳入了174

Neuroscience:玩3D视频游戏,或能帮助提高老年人认知能力!

http://www.medicalnewstoday.com/articles/303789.php

BMJ新闻:对于较差的健康护理服务,老年人为何不敢投诉?

据议会及卫生健康护理专员表示,在英国许多65岁以上的老人担心投诉护理不周会带来更差的结果,或不知道该如何提高其关注,而不敢投诉其较差的护理经历。

BMJ Open:老年人因胃肠炎需住院治疗的发生率和危险因素

研究者进行了一项研究,调查老年人胃肠炎住院治疗的发生率和危险因素。该纵形队列研究纳入了265 440名年龄≥45岁(平均年龄62.7岁)参与者,通过参与者自我报道方式,采集与感染性胃肠炎住院治疗相关的人口、健康和饮食信息等数据。研究者评估了感染性胃肠炎住院治疗发生率,校正相关混杂因素后,使用Cox回顾计算了两者间风险联系。研究数据显示,感染性胃肠炎发生率为6077/1 111 000人年,且随年龄

JAMA Intern Med:维生素D越多越好吗?

一项最新的研究指出,过量摄入维生素D并不会无限制地增强下肢功能,相反可能会导致老年疾病的发生。 这些结果发表在最近一期的《JAMA国际医学》杂志上,主要作者是其来自瑞士苏黎世大学的老年科主任Heike A Bischoff-Ferrari博士。在对200名最近一年来至少有过一次无创伤疾病70岁左右的男性与女性进行随机检测后,发现他们每月的维生素D3摄入量比正常摄入量(24000单位)高两倍。

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