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J Gastroen Hepatol:反流性食管病的鉴别方法——食管胃交界部收缩积分vs食管胃交界部形态学

2017-08-07 zhangfan MedSci原创

研究发现食管胃交界部收缩积分对反流性食管患者具有较好的区分度,食管下括约肌-膈脚分离在酸性反流患者中比较常见。食管胃交界部收缩积分对患者的鉴别能力超过食管胃交界部形态学

近日研究人员考察了食管胃交界部(EGJ)指标与阻抗- pH值,内镜下食管炎和食管下括约肌(LES)指标之间的关系。研究回顾了胃食管反流病(GERD)症状患者以及无症状的志愿者的阻抗–pH和内镜检查高分辨率数据。EGJ收缩积分(CI)通过三个呼吸周期的平均收缩积分得出。EGJ形态学根据食管下括约肌-膈脚分离程度进行评估。研究招募患者137人以及23名对照志愿者。统计发现,所以患者中共25名糜烂性反流病患者(ERD),16名非糜烂性反流患者(NERD),5名反流敏感患者,以及91名非反流病患者。研究发现,反流患者(22.6mmHg)的食管胃交界部收缩积分低于非反流病病人(50mmHg)以及健康志愿者(67mmHg),食管胃交界部收缩积分以39mmHg为界限,对于反流性食管患者的区分敏感性为77.8%,特异性为81.7%,AUC为0.814;对于糜烂性反流病患者,其食管下括约肌-膈脚分离明显。III级EGJ形态学与DeMeester评分高相关,各个EGJ形态亚组中,反流性食管病患者的食管胃交界部收缩积分最低。研究发现食管胃交界部收缩积分对反流性食管患者具有较好的区分度,食管下括约肌-膈脚分离

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    2017-08-18 许安
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    2017-08-12 yfjms

    学习了

    0

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    2017-08-09 gwc384
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    2017-08-09 zhouqu_8
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    2017-08-07 139****5926

    好好文章学习了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2071875, encodeId=b56e20e18750f, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Fri Aug 18 11:13:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711159, encodeId=d44f1e11159ea, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Jan 24 12:13:00 CST 2018, time=2018-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232665, encodeId=879b23266505, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Aug 12 00:39:03 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426791, encodeId=be6c1426e91db, content=<a href='/topic/show?id=221d685172' target=_blank style='color:#2F92EE;'>#EPA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Wed Aug 09 04:13:00 CST 2017, time=2017-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437229, encodeId=d142143e22933, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Aug 09 04:13:00 CST 2017, time=2017-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571594, encodeId=e57c15e15945e, content=<a href='/topic/show?id=41e33e76137' target=_blank style='color:#2F92EE;'>#反流#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37761, encryptionId=41e33e76137, topicName=反流)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Wed Aug 09 04:13:00 CST 2017, time=2017-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231161, encodeId=028c2311610e, content=好好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Mon Aug 07 15:18:13 CST 2017, time=2017-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231160, encodeId=c48423116078, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Mon Aug 07 15:11:12 CST 2017, time=2017-08-07, status=1, ipAttribution=)]
    2017-08-07 半夏微凉

    学习了谢谢分享

    0

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