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J Epidemiol Commun H:丹麦研究发现,大量烟酒不仅催老脸蛋儿,还有身体

2017-11-22 卢芳 中国循环杂志

近期来自丹麦一项对万余人追踪11年多的研究显示,大量烟酒催人老,老的不仅是脸蛋儿,还有身体。

为什么一样的年龄,有的人“冻龄”,有的人却油腻腻颇显老态?

近期来自丹麦一项对万余人追踪11年多的研究显示,大量烟酒催人老,老的不仅是脸蛋儿,还有身体。

怎么算老?该研究中用了四种与心血管病和(或)死亡风险增加有关的人体老化迹象来衡量:耳垂皱褶、眼睑黄斑瘤、角膜弓以及男士谢顶。

其中,这个耳垂皱褶,可不是睡觉压的,还有个别名叫Frank征,是指耳垂上出现耳屏到耳垂后外侧缘的褶皱,至少占总耳垂长度的1/3。角膜弓,是角膜局部脂质沉着所致,看着就老眼浑浊。

研究显示,不论男女,最常见的老便是有角膜弓,其中70岁以上的男士和80岁的女士60%都有;眼睑黄斑瘤最少见,50岁以上男女有5%有;发际线的退化在男士中最常见,40岁以上的男士八成都有发际线退化。

而进一步分析发现,那些烟不离手酒不离口的人,不仅看起来比实际年龄要大,而且有角膜弓、耳垂皱褶和眼睑黄斑瘤的风险持续增加。

比如,与每周饮酒7杯的人相比,对于每周饮酒≥28杯的女士而言,会增加33%有角膜弓的风险;对于每周饮酒≥35杯的男士而言,则会增加35%的看起来双眼浑浊的风险。

同样地,与不吸烟的人相比,那些每日20支,有15~30年烟龄的人,在女士会增加41%有角膜弓的风险,在男士会增加12%的风险。

不过研究没有发现少量饮酒会让人变老。

研究者认为,男性谢顶除了与大量烟酒有关外,还可能因为基因或雄激素水平强有力的作用。

此外,研究者指出,尽管在这项观察性研究中,考虑了一系列的混淆因素,但无法考量压力这种与心血管病和吸烟饮酒相关的因素。另外吸烟饮酒依赖受试者回忆自诉,还是有所偏差。尚不能得出因果关系的确切结论。

三毛说,我来不及认真地年轻,待明白过来时,只能选择认真地老去。也许,对于大多数人而言,已经不算年轻,但是把握住现在戒烟少酒,未尝不算是揪紧年轻的尾巴。

这项研究始于1976年,共纳入哥本哈根城市研究中的1.2位>20岁成年人,平均追踪11.5年。女士们平均每周饮酒2.6次,男士们11.4次;57%的女士和67%的男士吸烟。

原始出处:
Schou AL, Mølbak ML, Schnor P, et al. Alcohol consumption,smoking and development of visible age-related signs:a prospective cohort study. J Epidemiol Community Health. 2017 Dec; 71 (12):1177-1184.

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    2018-02-01 liuli5079
  3. 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    2017-11-26 Drhzm308

    谢谢.知道了

    0

  4. 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createdBy=7931272, createdName=liuli5079, createdTime=Thu Feb 01 01:25:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264374, encodeId=e69c2643e485, content=谢谢.知道了, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ad4c106013, createdName=Drhzm308, createdTime=Sun Nov 26 07:22:59 CST 2017, time=2017-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263938, encodeId=d1ee26393834, content=很好的文章., beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/20/71f908320db34f36cac4a7c807970775.jpg, createdBy=c93a2154620, createdName=平静的光芒, createdTime=Fri Nov 24 12:37:28 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263667, encodeId=666726366edf, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Nov 23 17:10:12 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263611, encodeId=97a6263611bb, content=很好的文章., beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/20/71f908320db34f36cac4a7c807970775.jpg, createdBy=c93a2154620, createdName=平静的光芒, createdTime=Thu Nov 23 12:22:48 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263545, encodeId=b251263545fb, content=学习谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Nov 23 08:10:10 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263539, encodeId=2c502635390d, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Nov 23 07:45:34 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263501, encodeId=94b926350116, content=吸烟有害健康.可是有谁听呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/21/9461f3b3c9f14e1d844256cdd08f2cf3.jpg, createdBy=a30f1426910, createdName=swfzhanggui, createdTime=Thu Nov 23 06:32:28 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263486, encodeId=f8c92634869c, content=好好好好好好好好就, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Nov 23 05:41:25 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-24 平静的光芒

    很好的文章.

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1753343, encodeId=207c1e53343fb, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Tue Feb 27 18:25:00 CST 2018, time=2018-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2087212, encodeId=08b5208e212d7, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, 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createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Nov 23 07:45:34 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263501, encodeId=94b926350116, content=吸烟有害健康.可是有谁听呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/21/9461f3b3c9f14e1d844256cdd08f2cf3.jpg, createdBy=a30f1426910, createdName=swfzhanggui, createdTime=Thu Nov 23 06:32:28 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263486, encodeId=f8c92634869c, content=好好好好好好好好就, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Nov 23 05:41:25 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

  6. 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createdTime=Thu Nov 23 12:22:48 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263545, encodeId=b251263545fb, content=学习谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Nov 23 08:10:10 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263539, encodeId=2c502635390d, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Nov 23 07:45:34 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263501, encodeId=94b926350116, content=吸烟有害健康.可是有谁听呢, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/21/9461f3b3c9f14e1d844256cdd08f2cf3.jpg, createdBy=a30f1426910, createdName=swfzhanggui, createdTime=Thu Nov 23 06:32:28 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263486, encodeId=f8c92634869c, content=好好好好好好好好就, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Nov 23 05:41:25 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 平静的光芒

    很好的文章.

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Nov 23 05:41:25 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 龙胆草

    学习谢谢

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Nov 23 05:41:25 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 清风拂面

    谢谢分享.学习了

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Nov 23 05:41:25 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 swfzhanggui

    吸烟有害健康.可是有谁听呢

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Nov 23 05:41:25 CST 2017, time=2017-11-23, status=1, ipAttribution=)]
    2017-11-23 yjs木玉

    好好好好好好好好就

    0

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JAHA:ACS患者PCI治疗后吸烟决定服用双倍剂量还是标准剂量氯吡格雷!

在吸烟者中,双倍剂量氯吡格雷减少了经皮冠状动脉介入治疗后主要心血管事件和支架血栓形成,并且没有增加大出血风险。这表明急性冠脉综合征患者服用氯吡格雷剂量应该个性化,同时应考虑到缺血和出血的风险。

J Epidemiol Community H:大量饮酒和吸烟与明显的衰老迹象有关

《流行病学与社区健康杂志》(Journal of Epidemiology & Community Health)网站上发表的一项研究表明,酗酒和吸烟与身体老化的明显迹象有关,而且看起来比实际年龄更大。

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