Baidu
map

神经科

订阅

MedSci主页 / 所有栏目 / 神经科

J Am Heart Assoc：抑郁症状好转卒中风险是否会降低？

2015-05-25 徐媛媛 MedSci原创

抑郁症神经
关注

尽管有研究表明,抑郁症状可预测中风发病率,而且抑郁症状是动态的，但目前尚不清楚的是如果抑郁症状好转卒中风险是否降低。 收纳了来自健康和退休试验研究项目16178名参与者，在1998--2010年间,参与者每两年接受一次随访调查。通过医生诊断参与者的自我报告以及校对流行病学研究中心抑郁量表[CES-D]（得分≥3症状较高）分别评估中风和抑郁症状。在随后的2年中，两次连续面谈来预测1192名参与者的

尽管有研究表明,抑郁症状可预测中风发病率,而且抑郁症状是动态的，但目前尚不清楚的是如果抑郁症状好转卒中风险是否降低。

收纳了来自健康和退休试验研究项目16178名参与者，在1998--2010年间,参与者每两年接受一次随访调查。通过医生诊断参与者的自我报告以及校对流行病学研究中心抑郁量表[CES-D]（得分≥3症状较高）分别评估中风和抑郁症状。在随后的2年中，两次连续面谈来预测1192名参与者的中风情况。研究人员使用Cox比例风险模型来调整人口、健康行为、慢性病和磨损。研究人员也对参与者进行了年龄(≥65岁)、种族或民族(非西班牙裔白人,非西班牙裔黑人、拉美裔)和性别的分层。

与参与者抑郁症状不稳定/无症状相比，中风风险稳定度高(调整后的危险比为2.14,95% CI 1.69-2.71)或者缓解中风风险(调整后的危险比为1.66,95% CI 1.22到2.26)。稳定高抑郁症状预测中风在所有子组。缓解抑郁症状预测女性中风风险增加(调整后的危险比为1.86,95% CI 1.30到2.66)，非西班牙裔白人(调整后的危险比为1.66,95%可信区间1.18到2.33)和略相关西班牙裔(调整后的危险比为2.36,95% CI 0.98到5.67)中风风险增加。

在这个群组,居高不下的抑郁症状与中风风险增加有关。

原始出处

Gilsanz P1, Walter S2, Tchetgen Tchetgen EJ3, Patton KK4, Moon JR5, Capistrant BD6, Marden JR1, Kubzansky LD1, Kawachi I1, Glymour MM7.Changes in Depressive Symptoms and Incidence of First Stroke Among Middle-Aged and Older US Adults.J Am Heart Assoc. 2015 May 13

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1281189, encodeId=5ef11281189fd, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355989, encodeId=6b7413559895d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434859, encodeId=61081434859ec, content=<a href='/topic/show?id=952a54980e5' target=_blank style='color:#2F92EE;'>#抑郁症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562310, encodeId=b644156231054, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24841, encodeId=f1ed2484162, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Mon May 25 19:02:00 CST 2015, time=2015-05-25, status=1, ipAttribution=)]
    2015-05-27 wmr111

    #卒中风险#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1281189, encodeId=5ef11281189fd, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355989, encodeId=6b7413559895d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434859, encodeId=61081434859ec, content=<a href='/topic/show?id=952a54980e5' target=_blank style='color:#2F92EE;'>#抑郁症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562310, encodeId=b644156231054, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24841, encodeId=f1ed2484162, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Mon May 25 19:02:00 CST 2015, time=2015-05-25, status=1, ipAttribution=)]
    2015-05-27 zhaojie88

    #ART#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1281189, encodeId=5ef11281189fd, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355989, encodeId=6b7413559895d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434859, encodeId=61081434859ec, content=<a href='/topic/show?id=952a54980e5' target=_blank style='color:#2F92EE;'>#抑郁症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562310, encodeId=b644156231054, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24841, encodeId=f1ed2484162, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Mon May 25 19:02:00 CST 2015, time=2015-05-25, status=1, ipAttribution=)]
    2015-05-27 zhouqu_8

    #抑郁症状#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1281189, encodeId=5ef11281189fd, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355989, encodeId=6b7413559895d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434859, encodeId=61081434859ec, content=<a href='/topic/show?id=952a54980e5' target=_blank style='color:#2F92EE;'>#抑郁症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562310, encodeId=b644156231054, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24841, encodeId=f1ed2484162, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Mon May 25 19:02:00 CST 2015, time=2015-05-25, status=1, ipAttribution=)]
    2015-05-27 slcumt

    #HEART#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1281189, encodeId=5ef11281189fd, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355989, encodeId=6b7413559895d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1434859, encodeId=61081434859ec, content=<a href='/topic/show?id=952a54980e5' target=_blank style='color:#2F92EE;'>#抑郁症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54980, encryptionId=952a54980e5, topicName=抑郁症状)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562310, encodeId=b644156231054, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed May 27 06:08:00 CST 2015, time=2015-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=24841, encodeId=f1ed2484162, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Mon May 25 19:02:00 CST 2015, time=2015-05-25, status=1, ipAttribution=)]
    2015-05-25 huaxipanxing

    看看

    0

相关资讯

J AFFECT DISORDERS：40至59岁乳腺癌患者易患抑郁症

先前的研究的结果发现通过辅助化治疗包括化疗、放疗、选择性雌激素受体调节剂(如三苯氧胺),第三代芳香化酶抑制剂(AIs;例如阿那曲唑、曲唑或依西美坦),和单克隆抗体(如trastuzumab)抑郁症在乳腺癌幸存者中的患病风险的结果不一致。因此我们以人群为基础在乳腺癌患者中接受辅助治疗后抑郁症的发病风险。 我们从台湾医疗保险研究数据库（NHIRD）中选择了36586名乳腺癌患者进行了一项回顾性研究

卫计委回应四川一医生自杀：无证据证明其有抑郁症

国家卫生计生委今日就《中国疾病预防控制工作进展(2015)报告》举行发布会。在回应四川一医院主任自杀事件时，专家董问天指出，现在没有更多的证据去证明那位医生有或者没有抑郁症。有媒体问及，最近因为四川的一个医院主任自杀的事件，媒体可能会关注到医务人员的精神状况。医患纠纷这么多，精神卫生这一块是不是应该提前介入，提早关注一下？以后会不会有这样一个对于医务人员精神卫生的关注？董问天表示，其实抑郁症和其他

AJP：西酞普兰+哌甲酯治疗老年抑郁症

目的：评价使用西酞普兰和哌甲酯联合使用可改善老年患者的抑郁、认知功能。 方法：该研究进行了16周的随机双盲对照试验，研究收纳了143位患有抑郁症的老年人并讲其随机分成三个治疗组：哌甲酯+安慰剂(N = 48),西酞普兰+安慰剂(N = 48),西酞普兰+哌甲酯(N = 47)。主要结局根据密尔顿抑郁量表（HAM-D）得分来评判。HAM-D得分≤6被定义为缓解。次要结局包括焦虑、淡漠、生活质量与认

JAMDA：抑郁症因素会增加死亡率？

背景：抑郁症与死亡率增高有一定的关系，但是这个关系是否是因果关系还不清楚。目标：该实验的目的是探索过去和现在抑郁症患者与死亡率之间的关联，并考虑意志薄弱的因素。设计、环境、参与人员：该研究为前瞻性纵向队列研究，我们调查了澳大利亚西部城市珀斯年龄在75岁以上且参与并完成第三次男性健康普查的2565名老人。主要数据来源：我们收集了来自截止到2013年6月17日澳大利亚死亡研究中心记录的由所有原因引起的

JAMA Psychia：抑郁症和糖尿病患者易患痴呆

近日，发表于国际杂志JAMA Psychiatry上的研究论文中，来自华盛顿大学医学院的研究者通过研究表示，抑郁症和2型糖尿病或许都和痴呆症的风险增加直接相关，而该风险在那些被诊断既是抑郁症又是糖尿病的患者中尤其高。糖尿病和严重抑郁在西方国家非常常见，大约有20%的糖尿病患者会患上抑郁症。研究者Dimitry Davydow表示，我们对240万丹麦居民进行了相关研究，检测了抑郁症患者、2型糖尿病患

Lancet：严重的焦虑症后易患继发性抑郁症！

背景：抑郁症和焦虑症是高度合并症，并且成为全球的疾病负担；然而，描述它们之前的联系的大规模的研究却很少。在这项回顾性研究中，主要目的是评估严重焦虑症对抑郁症过程及风险的影响。      方法：研究人员使用从丹麦的三个人口登记所收集到的数据，做了这个前瞻性、以人群为基础的队列研究，三个人口登记系统包括：丹麦民事登记系统、丹麦精神病中央登记册和丹麦国家医院登记处。

Baidu
map
Baidu
map
Baidu
map