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J Am Heart Assoc:糖尿病患者冠脉旁路移植术后卒中发生风险增加

2015-11-15 phylis 译 MedSci原创

背景:研究者进行一项全国性基于群体的队列研究,调查1型和2型糖尿病患者进行冠状动脉旁路移植术后发生卒中的长期风险。方法:在2000年到2011年间,在SWEDEHEART中登记患者中选取在瑞典行冠状动脉旁路移植术的患者。研究者排除了先前有卒中史及术后30天发生卒中或死亡的患者。在国家糖尿病登记记录中识别1型和2型糖尿病的患者。国家患者登记及死亡原因登记记录活得卒中发生(缺血性及出血性),各种原因的

背景:研究者进行一项全国性的、基于群体的队列研究,调查1型和2型糖尿病患者进行冠状动脉旁路移植术后发生卒中的长期风险。

方法:在2000年到2011年间,在SWEDEHEART中登记患者中选取在瑞典行冠状动脉旁路移植术的患者。研究者排除了先前有卒中史及术后30天发生卒中或死亡的患者。在国家糖尿病登记记录中识别1型和2型糖尿病的患者。国家患者登记及死亡原因登记记录卒中发生(缺血性及出血性)、各种原因的死亡。研究者应用多变量Cox回归评估糖尿病类型和卒中发生的风险。


结果:共有53820名糖尿病患者(1型糖尿病患者:714例; 2型糖尿病10054例;无糖尿病:43052例)。平均随访时间7.4年,8%(4296名)患者发生卒中:7.3%(52例)为1型糖尿病,9.1%(915例)为2型糖尿病患者,无糖尿病患者占7.7%(3329例)。1型糖尿病患者和2型糖尿病多变量调整HR(95% CI)分别为1.59(1.20-2.11),1.32(1.23-1.43)。

结论:与无糖尿病患者相比,1型和2型糖尿病患者进行冠状动脉旁路移植术后发生卒中的长期风险增加。

原文出处:

Nyström T, Holzmann MJ, Sartipy U. Long-Term Risk of Stroke in Patients With Type 1 and Type 2 Diabetes Following Coronary Artery Bypass Grafting.J Am Heart Assoc. 2015,Nov 9.

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    2016-10-12 cy0324
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    2015-11-17 zhaojie88
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    2015-11-17 slcumt

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