Baidu
map

Neurology:成年脑瘫患者非传染性疾病患病情况

2019-08-29 xing.T MedSci原创

由此可见,伴有CP的成年人发生非传染性疾病的风险增加,特别是心血管和呼吸系统疾病。这些研究结果强调了对CP患者的非传染性疾病方面需要临床警惕,以及进一步研究该人群中非传染性疾病的病因和治疗。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,该研究旨在比较伴有和不伴有脑瘫(CP)的成人之间非传染性疾病的发生率。

研究人员使用来自临床实践研究数据链的初级保健数据进行队列研究。按匹配集分层并针对潜在的混杂因素进行调整的Cox模型适用于比较伴有和不伴有CP的成人之间任何非传染性疾病、癌症、心血管疾病、2型糖尿病和呼吸系统疾病的风险。

该分析纳入了1705名患有CP的成年人和5115名没有CP的年龄、性别匹配的成年人。经调整的分析证据表明,与没有CP的成年人相比,伴有CP的成年人发生任何非传染性疾病的风险增加75%(风险比[HR]为1.75,95%可信区间[CI]为1.58-1.94)。具体而言,他们患心血管疾病(HR为1.76,95%CI为1.48-2.11)和呼吸系统疾病(HR为2.61,95%CI为2.14-3.19)的风险增加。没有证据表明患癌症或2型糖尿病的风险增加。

由此可见,伴有CP的成年人发生非传染性疾病的风险增加,特别是心血管和呼吸系统疾病。这些研究结果强调了对CP患者的非传染性疾病方面需要临床警惕,以及进一步研究该人群中非传染性疾病的病因和治疗。 

原始出处:

Jennifer M. Ryan,et al.Noncommunicable disease among adults with cerebral palsy A matched cohort study.Neurology.2019.https://n.neurology.org/content/early/2019/08/28/WNL.0000000000008199

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1997563, encodeId=92c5199e563b2, content=<a href='/topic/show?id=caf4992616a' target=_blank style='color:#2F92EE;'>#非传染性疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99261, encryptionId=caf4992616a, topicName=非传染性疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Thu May 21 22:42:00 CST 2020, time=2020-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000861, encodeId=a5d72000861ab, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Feb 25 10:42:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1911504, encodeId=cd06191150452, content=<a href='/topic/show?id=77b3259009f' target=_blank style='color:#2F92EE;'>#传染性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25900, encryptionId=77b3259009f, topicName=传染性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Jan 10 14:42:00 CST 2020, time=2020-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765082, encodeId=13361e6508229, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 09 14:42:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1997563, encodeId=92c5199e563b2, content=<a href='/topic/show?id=caf4992616a' target=_blank style='color:#2F92EE;'>#非传染性疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99261, encryptionId=caf4992616a, topicName=非传染性疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Thu May 21 22:42:00 CST 2020, time=2020-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000861, encodeId=a5d72000861ab, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Feb 25 10:42:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1911504, encodeId=cd06191150452, content=<a href='/topic/show?id=77b3259009f' target=_blank style='color:#2F92EE;'>#传染性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25900, encryptionId=77b3259009f, topicName=传染性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Jan 10 14:42:00 CST 2020, time=2020-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765082, encodeId=13361e6508229, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 09 14:42:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]
    2020-02-25 yinhl1978
  3. [GetPortalCommentsPageByObjectIdResponse(id=1997563, encodeId=92c5199e563b2, content=<a href='/topic/show?id=caf4992616a' target=_blank style='color:#2F92EE;'>#非传染性疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99261, encryptionId=caf4992616a, topicName=非传染性疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Thu May 21 22:42:00 CST 2020, time=2020-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000861, encodeId=a5d72000861ab, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Feb 25 10:42:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1911504, encodeId=cd06191150452, content=<a href='/topic/show?id=77b3259009f' target=_blank style='color:#2F92EE;'>#传染性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25900, encryptionId=77b3259009f, topicName=传染性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Jan 10 14:42:00 CST 2020, time=2020-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765082, encodeId=13361e6508229, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 09 14:42:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]
    2020-01-10 xzw113
  4. [GetPortalCommentsPageByObjectIdResponse(id=1997563, encodeId=92c5199e563b2, content=<a href='/topic/show?id=caf4992616a' target=_blank style='color:#2F92EE;'>#非传染性疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99261, encryptionId=caf4992616a, topicName=非传染性疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Thu May 21 22:42:00 CST 2020, time=2020-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2000861, encodeId=a5d72000861ab, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Tue Feb 25 10:42:00 CST 2020, time=2020-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1911504, encodeId=cd06191150452, content=<a href='/topic/show?id=77b3259009f' target=_blank style='color:#2F92EE;'>#传染性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25900, encryptionId=77b3259009f, topicName=传染性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Jan 10 14:42:00 CST 2020, time=2020-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1765082, encodeId=13361e6508229, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 09 14:42:00 CST 2019, time=2019-12-09, status=1, ipAttribution=)]

相关资讯

Lancet Respir Med:儿童时期肺功能轨迹是否延伸至成年?

2018年7月,英国和澳大利亚学者在《Lancet Respir Med》发表了3项基于人群的出生队列研究的回顾性分析,考察了学龄前到成年的肺功能轨迹及其与早期生活因素的相关性。

JCEM:儿童期被动吸烟与成年期骨骼健康有关

由此可见,吸烟父母的孩子成年后骨骼健康受损。

Intens Care Med:成年危重病人新发房颤分析

由此可见,危重病患者NOAF的定义和发生率差异很大,并确定了许多危险因素。NOAF似乎与不良结局相关,但数据非常有限,目前的治疗策略不是以证据为基础的。

成年男性无喉结患者气管内插管困难1例

患者,男性,55岁,因胃癌于2016年5月14日入院。体重75kg,身高172 cm,部队军人,有过专业体能训练,因“胃癌”拟在全麻下行胃癌根治术,麻醉前访视常规化验,心电图胸透正常。患者无基础疾病,无睡眠呼吸暂停综合征,无麻醉手术史。面部解剖正常,无短小颈假牙等困难插管特征,但无喉结,颈部肌肉高度发达。张口度4 cm,甲颏距离6.5 cm,Mallampati分级为Ⅱ级。麻醉前常规监测无创血压、

JAHA:儿童体重指数的变化与成年期静脉血栓栓塞的风险

由此可见,BMI持续高于平均水平的儿童在成年期患VTE的风险更高。虽然7-13岁的体重增加额外增加了VTE风险,但13岁时超重减轻会完全使升高的风险降至正常。

EASD2018丨10岁到成年期之间体质指数变化较大可独立于成年期体重指数与2型糖尿病风险相关

肥胖是2型糖尿病的重要危险因素。年龄、性别、种族差异、不同的体脂分布及遗传因素都可独立于体质指数(BMI)导致2型糖尿病风险的差异

Baidu
map
Baidu
map
Baidu
map