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间充质干细胞治疗类风湿关节炎贫血的临床研究

2016-04-08 佚名 医学论坛网

近期,河南省新乡市第一人民医院小军等研究了间充质干细胞治疗类风湿关节炎贫血的临床研究,研究发现,UCMSCs联合甲氨蝶呤治疗RA中度贫血,应用方便、安全、有效,可在临床推广。该文章发表于2016年02期《中国现代药物应用》上。 该研究旨在观察脐带间充质干细胞治疗类风湿关节炎(RA)贫血的临床疗效。 研究者们将20例患者随机分为试验组和对照组,各10例。试验组:第

近期,河南省新乡市第一人民医院小军等研究了间充质干细胞治疗类风湿关节炎贫血的临床研究,研究发现,UCMSCs联合甲氨蝶呤治疗RA中度贫血,应用方便、安全、有效,可在临床推广。该文章发表于2016年02期《中国现代药物应用》上。

该研究旨在观察脐带间充质干细胞治疗类风湿关节炎(RA)贫血的临床疗效。

研究者们将20例患者随机分为试验组和对照组,各10例。试验组:第1、2、3个月分别静脉输注第4~6代的脐带间充质干细胞(UCMSCs),细胞数为1×10~8,口服甲氨蝶呤片12.5 mg,1次/周;对照组口服甲氨蝶呤片12.5 mg,1次/周。观察6个月。观察治疗前后临床、实验室指标的变化及不良反应。

结果显示,两组患者治疗后疾病活动度评分(DAS28)、血沉(ESR)、C反应蛋白(CRP)较治疗前明显下降,差异具有统计学意义(P<0.05)。治疗后两组患者DAS评分、ESR、CRP比较,差异具有统计学意义(P<0.05)。试验组患者治疗后血红蛋白(Hb)较治疗前明显升高,差异具有统计学意义(P<0.05)。对照组患者治疗后Hb有所升高,但差异无统计学意义(P>0.05)。

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    2016-04-14 李继凯

    高大上的文章

    0

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    2016-04-14 李继凯

    值得学习

    0

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    2016-04-10 lmm397
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    2016-04-08 1de3b290m83(暂无匿称)

    干细胞

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