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BCL-2抑制剂Venetoclax获NICE批准用于慢性淋巴细胞白血病

2019-01-25 MedSci MedSci原创

Venclyxto是一线口服药物(每日一次),可选择性地抑制BCL-2蛋白的功能,恢复机体引发癌细胞自我毁灭的能力。Venclyxto已被推荐与利妥昔单抗联合治疗复发或难治性慢性淋巴细胞白血病的成人。

NICE推荐AbbVie的Venclyxto(venetoclax)用于治疗慢性淋巴细胞白血病(CLL)的成年患者。

目前慢性淋巴细胞白血病最常见的一线治疗方法是化疗,复发后选择有限。

Venclyxto是一线口服药物(每日一次),可选择性地抑制BCL-2蛋白的功能,恢复机体引发癌细胞自我毁灭的能力。Venclyxto已被推荐与利妥昔单抗联合治疗复发或难治性慢性淋巴细胞白血病的成人。

NICE健康技术评估中心主任Meindert Boysen说:"我们非常高兴地宣布,复发或难治性慢性淋巴细胞白血病患者有了新的治疗方案。

慢性淋巴细胞白血病是最常见的白血病形式,在英国每年诊断出约3500例新病例。幸运的是,据估计第一年有1000人将有资格获得Venclyxto。

原始出处:


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    2019-08-01 jklm09
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    2019-03-26 canlab
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    2019-01-27 fusion
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    2019-01-26 医者仁心5538

    学习了

    0

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