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复星医药携手Kite进军癌症T细胞免疫治疗市场

2017-01-11 佚名 证券时报

去年的“魏则西”事件,对大众进行了一次免疫细胞治疗法的普及。虽然该项技术尚不成熟,但是不能阻挡医药企业在这方面的布局。2017年1月10日晚,复星医药宣布与KP EU C.V.(以下简称“Kite”)成立合资公司携手开拓中国癌症T细胞免疫疗法市场。 复星医药公告称,全资子公司上海复星医药产业发展有限公司(以下简称“复星医药产业”)与Kite签订《中外合作经营合同》等,复星医药产业拟投资不超过

去年的“魏则西”事件,对大众进行了一次免疫细胞治疗法的普及。虽然该项技术尚不成熟,但是不能阻挡医药企业在这方面的布局。2017年1月10日晚,复星医药宣布与KP EU C.V.(以下简称“Kite”)成立合资公司携手开拓中国癌症T细胞免疫疗法市场。

复星医药公告称,全资子公司上海复星医药产业发展有限公司(以下简称“复星医药产业”)与Kite签订《中外合作经营合同》等,复星医药产业拟投资不超过等值8,000万美元(包括但不限于投资款及股东贷款)与Kite共同设立中外合作经营企业复星医药凯特生物科技(中国)有限公司。新公司的注册资本为4,000万美元,其中:复星医药产业拟以等值于2,000万美元的人民币现金认缴新公司注册资本,占新公司注册资本的50%;Kite拟以其相关产品和专有技术项下的独占商业使用权作价2,000万美元认缴新公司注册资本,占新公司注册资本的50%。

新公司设立和《技术许可协议》签署后,新公司将获得Kite就其研发的KTE-C19(一种向自体T细胞转导靶向人CD19的嵌合抗原受体用以治疗B细胞淋巴瘤及白血病的细胞治疗产品)于中国的商业化权利以及后续产品(即KITE-439及KITE-718)授权许可的优先选择权;新公司将根据KTE-C19的研发进展及市场情况向Kite支付3,500万美元的里程碑付款;新公司就后续产品(即KITE-439及KITE-718)将支付给Kite的全部费用(包括许可费以及全部里程碑付款,不包括销售提成)预计为14,000万美元。

目前,首个许可的产品KTE-C19已由Kite Pharma, Inc.(以下简称“Kite Pharma”)向美国食品药品监督管理局(即美国FDA)递交了T细胞免疫疗法KTE-C19的滚动新药申请,用于不适合自体干细胞移植的复发/难治性侵袭性B细胞非霍奇金淋巴瘤患者;后续产品目前尚处于临床前研发阶段。

Kite Pharma是一家临床阶段的生物制药公司,主要致力于研究、开发新的癌症免疫治疗产品。Kite Pharma与多家科研及临床机构形成长期战略合作,具有全球领先的肿瘤免疫细胞治疗产品研发能力;其主要产品包括表达嵌合抗原受体或T细胞受体的T细胞治疗产品Kite Pharma于美国纳斯达克证券交易所上市。

Kite Pharma在T细胞免疫治疗领域的研发处于全球领先,复星医药具有丰富的药品制造与研发经验,并在肿瘤治疗领域拥有多项在研产品。通过本次投资,可利用双方资源优势共同打造中国领先的T细胞免疫治疗产业平台,充分发挥本集团的行业经验及运营能力以及Kite Pharma全球领先的T细胞治疗产品研发能力,共同为中国肿瘤患者提供安全、有效的T细胞免疫治疗产品。

不过,T细胞免疫疗法相关产品的研发在癌症治疗领域处于前沿,目前全球范围内T细胞免疫疗法相关产品均尚处于临床试验阶段,相关技术和产品均存在不确定性。(生物谷Bioon.com)

相关会议推荐


2017”肿瘤免疫+”研讨会

会议时间:2017.3.10 -3.11      会议地点:上海

会议详情: http://www.bioon.com/z/2017tumor/

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    2017-01-13 cathymary
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    2017-01-13 shuangle

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肝癌是最难检测出的癌症种类之一,但是合成生物学家塔尔·丹尼诺有个惊人的想法:如果我们能够创造一个可食用的益生菌,将它“编译”并用来发现肝癌肿瘤呢?他的研究开拓了我们刚开始了解的细菌知识,这些知识涉及了它们的群体感应能力,或是当遇到临界物质时协作的能力。

Cancer Cell:为何癌症儿童深受放化疗毒害?

尽管近年来儿科肿瘤治疗取得了一些进展,但是化疗及放疗经常给这些年轻的孩子的脑、心及其他重要器官带来持久而严重的损伤,但是成年人的这些器官相对安全。这种差别迄今为止都没有得到合理的解释,这就导致医生需要平衡用药——他们需要给患儿使用足够高的剂量以杀死肿瘤细胞,同时又不能太高以至于带来严重副作用,但是由于重要器官还比较脆弱,婴儿和儿童的这个剂量范围非常窄。 如今,达纳法博癌症中心的科学家宣布他

Sci Adv:特殊表观遗传酶在癌症发生和扩散中或扮演关键的角色

图片摘自:wccftech.com 日前,刊登在国际杂志Science Advances上的一篇题为“KDM5 lysine demethylases are involved in maintenance of 3'UTR length”的研究报告中,来自耶鲁大学的研究人员通过研究阐明了表观遗传酶类在癌症发生过程中的一种特殊的角色。 为了更好地理解癌症的发生和扩散机制,研究者开始转向对

卫计委:没有数据证明雾霾和癌症发病有关

题记——亲们,你怎么看?近日,全国多地遭遇了雾霾侵袭。一些雾霾危害健康的言论不仅刷爆微信朋友圈,更使公众心中蒙上阴影。“雾霾引起癌症高发”等传言是否靠谱?为减少重污染、雾霾天气带来的健康危害,我们该怎么办?国家卫生计生委1月7日晚组织专家召开媒体专题座谈会,就公众关注的热点问题进行了回应。雾霾真能危害健康吗?“目前,我国没有证明雾霾和良、恶性肿瘤发病关系的临床研究结论和相关统计数据。雾霾对健康危害

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