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Plos One:计算机断层扫描能够预测老年急性肺栓塞的死亡率?

2017-06-11 MedSci MedSci原创

目前,计算机断层扫描肺血管造影(CTPA)不仅成为诊断急性肺栓塞(PE)的首选方法,其还可以对PE患者的风险进行分层。但是,迄今为止,尚无研究具体评估CTPA的预测价值,以评估老年急性PE患者的短期预后。近期,一项发表在杂志Plos One上的研究对这一问题进行了研究。此项研究为前瞻性多中心队列中研究,共选取了291例年龄≥65岁的急性症状性PE患者。研究结果为90天整体死亡率和PE相关死亡率、复

目前,计算机断层扫描肺血管造影(CTPA)不仅成为诊断急性肺栓塞(PE)的首选方法,其还可以对PE患者的风险进行分层。但是,迄今为止,尚无研究具体评估CTPA的预测价值,以评估老年急性PE患者的短期预后。近期,一项发表在杂志Plos One上的研究对这一问题进行了研究。

此项研究为前瞻性多中心队列中研究,共选取了291例年龄≥65岁的急性症状性PE患者。研究结果为90天整体死亡率和PE相关死亡率、复发性静脉血栓栓塞(VTE)以及住院时间(LOS)。使用生存分析评估计算机断层扫描阻塞指数(CTOI)和右心室(RV)与左心室(LV)直径比与死亡率的相关性以及VTE的复发率,同时将VTE复发、肺栓塞严重程度指数(PESI),和抗凝作为时变协变量。

此项研究结果显示:有15例患者在90天内死亡。 CTOI与90天整体死亡率无相关性(CTOI每10%调整后的风险比增加0.92;95%置信区间[CI] 0.70-1.21;P = 0.54),但CTOI与PE相关90-天死亡率有关(每10%CTOI调整亚危险比增加1.36;95%CI 1.03-1.81;P = 0.03)。 RV/LV直径比与整体或PE相关的90天死亡率无关。CTOI和RV/LV直径比与VTE复发和LOS显着相关。

此项研究表明:在老年急性PE患者中,CTOI与PE相关的90天死亡率相关,但与90天总死亡率无关。 RV/LV直径比不能够预测死亡率。上述两项措施均可预测VTE复发和LOS。评估的CTPA结果在死亡率预测方面似乎没有优于PESI。

原始出处:
Méan M, Tritschler T, et al. Association between computed tomography obstruction index and mortality in elderly patients with acute pulmonary embolism: A prospective validation study. PLoS One. 2017 Jun 8;12(6):e0179224. doi: 10.1371/journal.pone.0179224. eCollection 2017.

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    2017-12-18 bioon14
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    2017-06-12 184****9840

    学习了谢谢分享。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1789978, encodeId=0b571e8997809, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Sun Apr 08 08:03:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1716368, encodeId=277e1e16368ea, content=<a href='/topic/show?id=d68d911542f' target=_blank style='color:#2F92EE;'>#计算机#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91154, encryptionId=d68d911542f, topicName=计算机)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def632217870, createdName=bioon14, createdTime=Mon Dec 18 21:03:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1323476, encodeId=9d9113234e601, content=<a href='/topic/show?id=a94a52391e7' target=_blank style='color:#2F92EE;'>#急性肺栓塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52391, encryptionId=a94a52391e7, topicName=急性肺栓塞)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Tue Jun 13 06:03:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209691, encodeId=1b6c2096919d, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Mon Jun 12 07:13:40 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209613, encodeId=fa3f2096133a, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcEjDJv9IlQJJbicUksy5EgKakCUFgp5bGkVAqbW5kPPQzahBuoiabEnpHUX6gsjEoxuib7NWDXupmbxR04r5g4CqC/0, createdBy=5cd31467952, createdName=zhaolijian75, createdTime=Mon Jun 12 05:42:12 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209486, encodeId=6adf20948676, content=受益匪浅,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jun 11 19:21:22 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209462, encodeId=a77d20946228, content=又学习了。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuIjZYTAgkEia1SFuoeAByVaQC8uXegibpJEV2Q7SqhpDINJicNiaU5pYicYmy5WsI8l5hDribViac2A1BQ9/0, createdBy=c36f1724608, createdName=hfuym10906, createdTime=Sun Jun 11 17:33:30 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209444, encodeId=4f0f2094440f, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQplCaQGBmjHytXQqvsuocO2uV2lOAaJibzDafJudKToVfU12LzwArHDb4TSrmU2hk5Qxzc6icoicBK3Dg/0, createdBy=a7901968505, createdName=明心见性, createdTime=Sun Jun 11 15:31:05 CST 2017, time=2017-06-11, status=1, ipAttribution=)]
    2017-06-12 zhaolijian75

    学习了,谢谢

    0

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    2017-06-11 清风拂面

    受益匪浅,谢谢分享

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1789978, encodeId=0b571e8997809, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Sun Apr 08 08:03:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1716368, encodeId=277e1e16368ea, content=<a href='/topic/show?id=d68d911542f' target=_blank style='color:#2F92EE;'>#计算机#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91154, encryptionId=d68d911542f, topicName=计算机)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def632217870, createdName=bioon14, createdTime=Mon Dec 18 21:03:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1323476, encodeId=9d9113234e601, content=<a href='/topic/show?id=a94a52391e7' target=_blank style='color:#2F92EE;'>#急性肺栓塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52391, encryptionId=a94a52391e7, topicName=急性肺栓塞)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Tue Jun 13 06:03:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209691, encodeId=1b6c2096919d, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Mon Jun 12 07:13:40 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209613, encodeId=fa3f2096133a, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcEjDJv9IlQJJbicUksy5EgKakCUFgp5bGkVAqbW5kPPQzahBuoiabEnpHUX6gsjEoxuib7NWDXupmbxR04r5g4CqC/0, createdBy=5cd31467952, createdName=zhaolijian75, createdTime=Mon Jun 12 05:42:12 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209486, encodeId=6adf20948676, content=受益匪浅,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jun 11 19:21:22 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209462, encodeId=a77d20946228, content=又学习了。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuIjZYTAgkEia1SFuoeAByVaQC8uXegibpJEV2Q7SqhpDINJicNiaU5pYicYmy5WsI8l5hDribViac2A1BQ9/0, createdBy=c36f1724608, createdName=hfuym10906, createdTime=Sun Jun 11 17:33:30 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209444, encodeId=4f0f2094440f, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQplCaQGBmjHytXQqvsuocO2uV2lOAaJibzDafJudKToVfU12LzwArHDb4TSrmU2hk5Qxzc6icoicBK3Dg/0, createdBy=a7901968505, createdName=明心见性, createdTime=Sun Jun 11 15:31:05 CST 2017, time=2017-06-11, status=1, ipAttribution=)]
    2017-06-11 hfuym10906

    又学习了。。。。。

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1789978, encodeId=0b571e8997809, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Sun Apr 08 08:03:00 CST 2018, time=2018-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1716368, encodeId=277e1e16368ea, content=<a href='/topic/show?id=d68d911542f' target=_blank style='color:#2F92EE;'>#计算机#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91154, encryptionId=d68d911542f, topicName=计算机)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def632217870, createdName=bioon14, createdTime=Mon Dec 18 21:03:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1323476, encodeId=9d9113234e601, content=<a href='/topic/show?id=a94a52391e7' target=_blank style='color:#2F92EE;'>#急性肺栓塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52391, encryptionId=a94a52391e7, topicName=急性肺栓塞)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Tue Jun 13 06:03:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209691, encodeId=1b6c2096919d, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Mon Jun 12 07:13:40 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209613, encodeId=fa3f2096133a, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcEjDJv9IlQJJbicUksy5EgKakCUFgp5bGkVAqbW5kPPQzahBuoiabEnpHUX6gsjEoxuib7NWDXupmbxR04r5g4CqC/0, createdBy=5cd31467952, createdName=zhaolijian75, createdTime=Mon Jun 12 05:42:12 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209486, encodeId=6adf20948676, content=受益匪浅,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jun 11 19:21:22 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209462, encodeId=a77d20946228, content=又学习了。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuIjZYTAgkEia1SFuoeAByVaQC8uXegibpJEV2Q7SqhpDINJicNiaU5pYicYmy5WsI8l5hDribViac2A1BQ9/0, createdBy=c36f1724608, createdName=hfuym10906, createdTime=Sun Jun 11 17:33:30 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209444, encodeId=4f0f2094440f, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQplCaQGBmjHytXQqvsuocO2uV2lOAaJibzDafJudKToVfU12LzwArHDb4TSrmU2hk5Qxzc6icoicBK3Dg/0, createdBy=a7901968505, createdName=明心见性, createdTime=Sun Jun 11 15:31:05 CST 2017, time=2017-06-11, status=1, ipAttribution=)]
    2017-06-11 明心见性

    学习了!

    0

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