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J Infect Dis:水痘带状疱疹病毒血管病变研究进展J Infect Dis:水痘带状疱疹病毒血管病变研究进展

2018-09-27 MedSci MedSci原创

奥罗拉科罗拉多大学医学院眼科的Nagel MA近日在J Infect Dis发表了一篇综述文章,作者系统介绍了水痘带状疱疹病毒的研究现状,并对其在血管疾病中的作用进行了讨论。

奥罗拉科罗拉多大学医学院眼科的Nagel MA近日在J Infect Dis发表了一篇综述文章,作者系统介绍了水痘带状疱疹病毒的研究现状,并对其在血管疾病中的作用进行了讨论。

水痘带状疱疹病毒(VZV)是一种普遍存在的人类α疱疹病毒,可引发水痘,然后在神经节神经元中潜伏。在老年人和免疫受损的个体中,VZV会重新激活并且通常产生带状疱疹。对VZV血管病变患者的研究已经确定了关键的临床特征、影像学和实验特征等,可以帮助诊断和治疗。补充研究进一步扩展了VZV血管病变的范围,包括颅外循环,并确定了其发病机制。

随着人口老龄化日益增加,同时VZV再次激活表现为带状疱疹,也是中风和心肌梗死的危险因素。鉴于以上原因,在不管有无带状疱疹的血管疾病中,VZV被认为是一个潜在原因。这个认识对于降低相关发病率和死亡率至关重要,因为可以用抗病毒的治疗方法对VZV血管病变进行治疗。

原文出处:

Nagel, M.A. and A.N. Bubak, Varicella Zoster Virus Vasculopathy. J Infect Dis, 2018. 218(suppl_2): p. S107-s112.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

 

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    2019-03-14 仁心济世
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    2018-09-29 heli0118

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