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Diabetes Care:COVID-19大流行期间美国2型糖尿病老年人抑郁、孤独和失眠症状的患病率变化

2021-11-14 MedSci原创 MedSci原创

在COVID-19期间,患有糖尿病的老年人中轻度或重度抑郁症状的患病率是大流行之前的1.6倍以上。

2020年1月21日,美国确认了首例2019冠状病毒病 (COVID-19)。2020年3月19日,加利福尼亚州是第一个发布居家令的州,大多数州在随后的几个月中发布了类似的命令。自此,大部分美国人口的面对面社交接触显著减少。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,这项研究旨在评估2016年至2020年期间老年2型糖尿病患者抑郁症状、孤独感和失眠的患病率变化情况,并评估这些疾病的危险因素,包括人口统计学、多发病率、BMI、治疗组和COVID-19前的测量分数。

这是一项前瞻性、观察性研究,参与者来自LookAHEAD(糖尿病健康行动)队列研究。数据来自COVID-19之前的两项评估(V1:2016年4月至2018年6月和V2:2018年2月至2020年2月)和COVID-19期间的一项评估(V3:2020年7月至12月)。研究人员进行了调查以评估抑郁症状、孤独感和失眠情况。

该研究共纳入了2829名成人(63.2%为女性,60.6%为白人,平均[SD]年龄为75.6[6.0]岁)。在两次大流行前就诊之间,轻度或重度抑郁症状的患病率没有显著变化(P=0.88),但从COVID-19前期到流行期间显著增加(V2时为19.3%,V3时为30.4%;P<0.001)。V3时出现轻度或重度抑郁症状的较高几率与女性相关(调整后的比值比[OR]为1.4[95%CI为1.1-1.7]),研究人员确定了非西班牙裔白人(OR为1.4[95%CI为1.1-1.7]))、肥胖(OR为1.3[95%CI为1.0-1.5]),并且在V1(OR为4.0[95%CI为2.9-5.4])、V2(OR为4.4[95%CI为3.2-5.9])报告轻度或更严重的抑郁症状]),或两次就诊(OR为13.4[95%CI为9.7-18.4])。孤独感的患病率从V1时的12.3%增加到V3时的22.1%(P<0.001),而失眠的患病率在各次随访中保持稳定在31.5-33.3%。

由此可见,在COVID-19期间,患有糖尿病的老年人中轻度或重度抑郁症状的患病率是大流行之前的1.6倍以上。

原始出处:
 
Ariana M. Chao,et al.Changes in the Prevalence of Symptoms of Depression, Loneliness, and Insomnia in U.S. Older Adults With Type 2 Diabetes During the COVID-19 Pandemic: The Look AHEAD Study.Diabetes care.2021.https://care.diabetesjournals.org/content/early/2021/11/08/dc21-1179

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    2022-06-13 柳叶一刀
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    2021-11-17 1461fe16m02

    受益匪浅

    0

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  7. [GetPortalCommentsPageByObjectIdResponse(id=2038015, encodeId=b6a4203801578, content=<a href='/topic/show?id=bbf54429306' target=_blank style='color:#2F92EE;'>#失眠症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44293, encryptionId=bbf54429306, topicName=失眠症状)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/XhttJCp4Aq9gKA5n4v9elclQlVQTDenMiaEiadlI5D3gtmfSiaicoIY4ZsuibrQKLibDdxBKVY8oS6B2FicqJlT93clow/132, createdBy=03202500144, createdName=ms7258648636991762, createdTime=Sun Jan 16 19:50:45 CST 2022, time=2022-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1761765, encodeId=6a1c1e61765d5, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Jun 13 11:50:45 CST 2022, time=2022-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1639962, encodeId=8f88163996272, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Sep 21 08:50:45 CST 2022, time=2022-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1902670, encodeId=2e5319026e0ac, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Thu Dec 16 05:50:45 CST 2021, time=2021-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1071120, encodeId=0b8310e11206e, content=受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201022/560f15a0277d43b6a97093df9d0bd9c6/495b8d7c43964f24a256a019fb92ab8e.jpg, createdBy=4aac5114077, createdName=1461fe16m02, createdTime=Wed Nov 17 15:17:38 CST 2021, time=2021-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250773, encodeId=ebc91250e732b, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Tue Nov 16 05:50:45 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299394, encodeId=04551299394ea, content=<a href='/topic/show?id=59d64429252' target=_blank style='color:#2F92EE;'>#失眠症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44292, encryptionId=59d64429252, topicName=失眠症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4a4d285, createdName=日月, createdTime=Tue Nov 16 05:50:45 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070326, encodeId=67b610e0326a2, content=这个研究好。, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cbcd5675699, createdName=moyanju2796, createdTime=Mon Nov 15 08:15:46 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2021-11-16 日月
  8. [GetPortalCommentsPageByObjectIdResponse(id=2038015, encodeId=b6a4203801578, content=<a href='/topic/show?id=bbf54429306' target=_blank style='color:#2F92EE;'>#失眠症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44293, encryptionId=bbf54429306, topicName=失眠症状)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/XhttJCp4Aq9gKA5n4v9elclQlVQTDenMiaEiadlI5D3gtmfSiaicoIY4ZsuibrQKLibDdxBKVY8oS6B2FicqJlT93clow/132, createdBy=03202500144, createdName=ms7258648636991762, createdTime=Sun Jan 16 19:50:45 CST 2022, time=2022-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1761765, encodeId=6a1c1e61765d5, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Jun 13 11:50:45 CST 2022, time=2022-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1639962, encodeId=8f88163996272, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Sep 21 08:50:45 CST 2022, time=2022-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1902670, encodeId=2e5319026e0ac, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Thu Dec 16 05:50:45 CST 2021, time=2021-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1071120, encodeId=0b8310e11206e, content=受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201022/560f15a0277d43b6a97093df9d0bd9c6/495b8d7c43964f24a256a019fb92ab8e.jpg, createdBy=4aac5114077, createdName=1461fe16m02, createdTime=Wed Nov 17 15:17:38 CST 2021, time=2021-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250773, encodeId=ebc91250e732b, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Tue Nov 16 05:50:45 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299394, encodeId=04551299394ea, content=<a href='/topic/show?id=59d64429252' target=_blank style='color:#2F92EE;'>#失眠症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44292, encryptionId=59d64429252, topicName=失眠症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4a4d285, createdName=日月, createdTime=Tue Nov 16 05:50:45 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070326, encodeId=67b610e0326a2, content=这个研究好。, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cbcd5675699, createdName=moyanju2796, createdTime=Mon Nov 15 08:15:46 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2021-11-15 moyanju2796

    这个研究好。

    0

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