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N Z Med J:有效!库克群岛妊娠期糖尿病筛查显成效

2015-04-26 Mechront 译 MedSci原创

Aung YY等人纳入了库克群岛从2009年1月至2012年12月行产前检查且符合纳入标准的孕妇。在24-28周孕,行75 g口服葡萄糖耐量试验(妊娠期糖尿病诊断标准:空腹血糖大于或等于5.2mol/ L或餐后两个小时血糖大于或等于8.0mmol/ L;筛查是阳性,但是不符合妊娠期糖尿病的诊断则判定为妊娠期糖耐量受损)之后,行非空腹50克葡萄糖试验挑战(妊娠期糖尿病诊断标准:餐后一小时血糖大于或等

Aung YY等人纳入了库克群岛从2009年1月至2012年12月行产前检查且符合纳入标准的孕妇。在24-28周孕,行75 g口服葡萄糖耐量试验(妊娠期糖尿病诊断标准:空腹血糖大于或等于5.2mol/ L或餐后两个小时血糖大于或等于8.0mmol/ L;筛查是阳性,但是不符合妊娠期糖尿病的诊断则判定为妊娠期糖耐量受损)之后,行非空腹50克葡萄糖试验挑战(妊娠期糖尿病诊断标准:餐后一小时血糖大于或等于7.8mmol/ L)。

在试验最后阶段,妊娠期糖尿病筛查率从49.0%增至99.6%。有646名接受了50克葡萄糖试验挑战,其中186/646 (28.8%)试验结果阳性;183名行了口服葡萄糖耐量试验;89/646 (13.8%)结果提示妊娠期糖耐量受损;94/646 (13.9%)确诊妊娠期糖尿病。对其随访妊娠结局发现,妊娠期糖尿病孕妇体重平均增加6 kg,正常糖耐量孕妇体重平均增加10 kg;其对应的剖宫产率分别为妊娠期糖尿病:25%、正常糖耐量:11%;新生儿出生体重两组间无统计学意义。有59名妊娠期糖尿病孕妇产后6周行葡萄糖耐量试验,发现21(35.6%)为糖尿病患者。

该研究结果表明,库克群岛妊娠期糖尿病筛查率很高,对其进行的管理可有效地降低孕产妇和胎儿体重增加。

原始出处:

Aung YY, Sowter M, Kenealy T, Herman J, Ekeroma A.Gestational diabetes mellitus screening, management and outcomes in the Cook Islands.N Z Med J. 2015. 128(1412): 21-8.

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    2015-04-27 101.81.67.**

    长期效应?

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