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Circulation:健康相关的生活质量可预测心衰患者死亡风险

2021-06-04 MedSci原创 MedSci原创

HRQL是全球不同地区、轻度和重度症状性 HF 以及射血分数保留或降低的患者的全因死亡和 HF 住院的强有力的独立预测因子

心力衰竭(HF)患者的死亡率一直居高不下,健康相关的生活质量(HRQL)也普遍较差,但是很少有关于HF患者的HRQL以及HRQL和患者死亡率的相关性的数据。

Johansson等人采用堪萨斯城心肌病问卷–12(KCCQ-12)记录了G-CHF研究从全球8个地区40个国家招募的23291位HF患者的HRQL。比较了不同地区的标准化 KCCQ-12 总分(根据年龄、性别和 HF 严重程度进行了调整;分数从 0 到 100,分数越高表示 HRQL 越好)。采用多变量 Cox 回归评估 KCCQ-12 总分与中位随访 1.6 年期间全因死亡和心衰住院的复合结局以及每个组成部分的关联。

受试者平均65岁,61%的男性,40%的有NYHA III或IV级症状;46%的患者的左心室射血分数≥40%。地区间的平均HRQL有所不同:非洲最低(平均±SE:39.5±0.3)、西欧最高(62.5±0.4)

不同KCCQ-12等级的患者临床预后:A 24个月存活率;B 24个月无HF住院存活率;C 24个月无HF住院或死亡存活率

随访期间,共有4460人(19%)死亡,3885人(17%)因心衰住院,6949人(30%)发生了任一事件。较低的 KCCQ-12 总分与所有结果的较高风险相关。KCCQ-12 总分每降低10分后死亡的调整风险比(HR)为1.18

不同地区的全因死亡风险比

虽然在所有地区都观察到了上述关联,但在南亚、南美洲和非洲则不太明显(在南亚最弱[HR 1.08]、在东欧最强[1.31],P<0.0001)。较低的HRQL可预测NYHA I/II级(HR 1.17)和NYHA III/IV级(1.14)患者的死亡风险(P=0.13),还是ANHA I/II级患者发生复合结果的较强的预测指标(HR 1.15 vs 1.09[III/IV级],P<0.0001)。此外,较低的HRQL对射血分数≥40%的患者的死亡风险的影响大于射血分数<40%的患者(HR 1.23 vs 1.15,P<0.0001)。

根据NYHA等级和KCCQ-12总分分组的24个月年龄、性别标准化的死亡率

综上所述,HRQL是全球不同地区、轻度和重度症状性 HF 以及射血分数保留或降低的患者的全因死亡和 HF 住院的强有力的独立预测因子

在线免费使用:

堪萨斯城心肌病调查问卷(KCCQ-23问卷)

简易堪萨斯城心肌病调查问卷(KCCQ-12问卷)

原始出处:

Isabelle Johansson, et al. Health-Related Quality of Life and Mortality in Heart Failure: The Global Congestive Heart Failure Study of 23 000 Patients From 40 Countries. Circulation. 2021;143:2129–2142. https://doi.org/10.1161/CIRCULATIONAHA.120.050850

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    2021-08-10 Doctoryangbai

    学习了

    0

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createdBy=31545513340, createdName=ms1000001134092964, createdTime=Fri Jun 04 11:01:09 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970828, encodeId=3e729e082847, content=科学性, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210604/719495b6f46e43bbbd0b0e6b82640536/303611f29cbf4ba389448a64928ffcb9.jpg, createdBy=013d1365052, createdName=dongquanhai, createdTime=Fri Jun 04 10:45:08 CST 2021, time=2021-06-04, status=1, ipAttribution=)]
    2021-06-06 小小医者

    #心衰##心力衰竭#与生活质量是有因有果,二者是关联的,生活质量下降,预后肯定不佳

    2

    展开2条回复
  4. 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createdName=Doctoryangbai, createdTime=Tue Aug 10 14:07:12 CST 2021, time=2021-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971339, encodeId=8b9e9e133988, content=<a href='/topic/show?id=f5cb5192610' target=_blank style='color:#2F92EE;'>#心衰#</a><a href='/topic/show?id=072c5088466' target=_blank style='color:#2F92EE;'>#心力衰竭#</a>与生活质量是有因有果,二者是关联的,生活质量下降,预后肯定不佳, beContent=null, objectType=article, channel=null, level=null, likeNumber=291, replyNumber=2, topicName=null, topicId=null, topicList=[TopicDto(id=51926, encryptionId=f5cb5192610, topicName=心衰), TopicDto(id=50884, encryptionId=072c5088466, topicName=心力衰竭)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sun Jun 06 18:17:23 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976779, encodeId=278d9e677933, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/cdfaaa05402e44528b0355026d1ecc97/7ae8fb9c61da488fb9ab1d85bfdad744.jpg, createdBy=8cdb5533994, createdName=蓝色贝鱼88, createdTime=Fri Jun 25 13:12:38 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971302, encodeId=ac209e130282, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bd984965877, createdName=1453df99m58暂无昵称, createdTime=Sun Jun 06 15:27:52 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256089, encodeId=651d12560892f, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373526, encodeId=f5c113e3526c7, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970846, encodeId=82a99e084663, content=挺好的<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=169, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e565513362, createdName=ms9000001913283834, createdTime=Fri Jun 04 11:28:00 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970834, encodeId=84049e0834eb, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31545513340, createdName=ms1000001134092964, createdTime=Fri Jun 04 11:01:09 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970828, encodeId=3e729e082847, content=科学性, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210604/719495b6f46e43bbbd0b0e6b82640536/303611f29cbf4ba389448a64928ffcb9.jpg, createdBy=013d1365052, createdName=dongquanhai, createdTime=Fri Jun 04 10:45:08 CST 2021, time=2021-06-04, status=1, ipAttribution=)]
    2021-06-25 蓝色贝鱼88

    #学习#学习了

    0

  5. 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encodeId=278d9e677933, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/cdfaaa05402e44528b0355026d1ecc97/7ae8fb9c61da488fb9ab1d85bfdad744.jpg, createdBy=8cdb5533994, createdName=蓝色贝鱼88, createdTime=Fri Jun 25 13:12:38 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971302, encodeId=ac209e130282, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bd984965877, createdName=1453df99m58暂无昵称, createdTime=Sun Jun 06 15:27:52 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256089, encodeId=651d12560892f, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373526, encodeId=f5c113e3526c7, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, 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createdBy=31545513340, createdName=ms1000001134092964, createdTime=Fri Jun 04 11:01:09 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970828, encodeId=3e729e082847, content=科学性, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210604/719495b6f46e43bbbd0b0e6b82640536/303611f29cbf4ba389448a64928ffcb9.jpg, createdBy=013d1365052, createdName=dongquanhai, createdTime=Fri Jun 04 10:45:08 CST 2021, time=2021-06-04, status=1, ipAttribution=)]
    2021-06-06 1453df99m58暂无昵称

    学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1983722, encodeId=875b1983e223c, content=<a href='/topic/show?id=628553048e3' target=_blank style='color:#2F92EE;'>#患者死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53048, encryptionId=628553048e3, topicName=患者死亡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sun Sep 19 01:40:15 CST 2021, time=2021-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1006636, encodeId=b1f5100663629, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLyXfB3bOYOsDt885AsrYWhiaRtRdPh9aZlXugm7XErBVXusv5fJLIKWTicmjSQcOibDiaLzE2YMD44PA/132, createdBy=49f71976501, 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256089, encodeId=651d12560892f, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373526, encodeId=f5c113e3526c7, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, 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createdBy=31545513340, createdName=ms1000001134092964, createdTime=Fri Jun 04 11:01:09 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970828, encodeId=3e729e082847, content=科学性, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210604/719495b6f46e43bbbd0b0e6b82640536/303611f29cbf4ba389448a64928ffcb9.jpg, createdBy=013d1365052, createdName=dongquanhai, createdTime=Fri Jun 04 10:45:08 CST 2021, time=2021-06-04, status=1, ipAttribution=)]
  7. 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createdName=Doctoryangbai, createdTime=Tue Aug 10 14:07:12 CST 2021, time=2021-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971339, encodeId=8b9e9e133988, content=<a href='/topic/show?id=f5cb5192610' target=_blank style='color:#2F92EE;'>#心衰#</a><a href='/topic/show?id=072c5088466' target=_blank style='color:#2F92EE;'>#心力衰竭#</a>与生活质量是有因有果,二者是关联的,生活质量下降,预后肯定不佳, beContent=null, objectType=article, channel=null, level=null, likeNumber=291, replyNumber=2, topicName=null, topicId=null, topicList=[TopicDto(id=51926, encryptionId=f5cb5192610, topicName=心衰), TopicDto(id=50884, encryptionId=072c5088466, topicName=心力衰竭)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sun Jun 06 18:17:23 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976779, encodeId=278d9e677933, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/cdfaaa05402e44528b0355026d1ecc97/7ae8fb9c61da488fb9ab1d85bfdad744.jpg, createdBy=8cdb5533994, createdName=蓝色贝鱼88, createdTime=Fri Jun 25 13:12:38 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971302, encodeId=ac209e130282, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bd984965877, createdName=1453df99m58暂无昵称, createdTime=Sun Jun 06 15:27:52 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256089, encodeId=651d12560892f, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373526, encodeId=f5c113e3526c7, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970846, encodeId=82a99e084663, content=挺好的<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=169, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e565513362, createdName=ms9000001913283834, createdTime=Fri Jun 04 11:28:00 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970834, encodeId=84049e0834eb, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31545513340, createdName=ms1000001134092964, createdTime=Fri Jun 04 11:01:09 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970828, encodeId=3e729e082847, content=科学性, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210604/719495b6f46e43bbbd0b0e6b82640536/303611f29cbf4ba389448a64928ffcb9.jpg, createdBy=013d1365052, createdName=dongquanhai, createdTime=Fri Jun 04 10:45:08 CST 2021, time=2021-06-04, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1983722, encodeId=875b1983e223c, content=<a href='/topic/show?id=628553048e3' target=_blank style='color:#2F92EE;'>#患者死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53048, encryptionId=628553048e3, topicName=患者死亡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sun Sep 19 01:40:15 CST 2021, time=2021-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1006636, encodeId=b1f5100663629, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLyXfB3bOYOsDt885AsrYWhiaRtRdPh9aZlXugm7XErBVXusv5fJLIKWTicmjSQcOibDiaLzE2YMD44PA/132, createdBy=49f71976501, createdName=Doctoryangbai, createdTime=Tue Aug 10 14:07:12 CST 2021, time=2021-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971339, encodeId=8b9e9e133988, content=<a href='/topic/show?id=f5cb5192610' target=_blank style='color:#2F92EE;'>#心衰#</a><a href='/topic/show?id=072c5088466' target=_blank style='color:#2F92EE;'>#心力衰竭#</a>与生活质量是有因有果,二者是关联的,生活质量下降,预后肯定不佳, beContent=null, objectType=article, channel=null, level=null, likeNumber=291, replyNumber=2, topicName=null, topicId=null, topicList=[TopicDto(id=51926, encryptionId=f5cb5192610, topicName=心衰), TopicDto(id=50884, encryptionId=072c5088466, topicName=心力衰竭)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sun Jun 06 18:17:23 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976779, encodeId=278d9e677933, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/cdfaaa05402e44528b0355026d1ecc97/7ae8fb9c61da488fb9ab1d85bfdad744.jpg, createdBy=8cdb5533994, createdName=蓝色贝鱼88, createdTime=Fri Jun 25 13:12:38 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971302, encodeId=ac209e130282, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bd984965877, createdName=1453df99m58暂无昵称, createdTime=Sun Jun 06 15:27:52 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256089, encodeId=651d12560892f, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373526, encodeId=f5c113e3526c7, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970846, encodeId=82a99e084663, content=挺好的<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=169, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e565513362, createdName=ms9000001913283834, createdTime=Fri Jun 04 11:28:00 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970834, encodeId=84049e0834eb, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31545513340, createdName=ms1000001134092964, createdTime=Fri Jun 04 11:01:09 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970828, encodeId=3e729e082847, content=科学性, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210604/719495b6f46e43bbbd0b0e6b82640536/303611f29cbf4ba389448a64928ffcb9.jpg, createdBy=013d1365052, createdName=dongquanhai, createdTime=Fri Jun 04 10:45:08 CST 2021, time=2021-06-04, status=1, ipAttribution=)]
    2021-06-04 ms9000001913283834

    挺好的#学习#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1983722, encodeId=875b1983e223c, content=<a href='/topic/show?id=628553048e3' target=_blank style='color:#2F92EE;'>#患者死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53048, encryptionId=628553048e3, topicName=患者死亡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sun Sep 19 01:40:15 CST 2021, time=2021-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1006636, encodeId=b1f5100663629, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLyXfB3bOYOsDt885AsrYWhiaRtRdPh9aZlXugm7XErBVXusv5fJLIKWTicmjSQcOibDiaLzE2YMD44PA/132, createdBy=49f71976501, createdName=Doctoryangbai, createdTime=Tue Aug 10 14:07:12 CST 2021, time=2021-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971339, encodeId=8b9e9e133988, content=<a href='/topic/show?id=f5cb5192610' target=_blank style='color:#2F92EE;'>#心衰#</a><a href='/topic/show?id=072c5088466' target=_blank style='color:#2F92EE;'>#心力衰竭#</a>与生活质量是有因有果,二者是关联的,生活质量下降,预后肯定不佳, beContent=null, objectType=article, channel=null, level=null, likeNumber=291, replyNumber=2, topicName=null, topicId=null, topicList=[TopicDto(id=51926, encryptionId=f5cb5192610, topicName=心衰), TopicDto(id=50884, encryptionId=072c5088466, topicName=心力衰竭)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sun Jun 06 18:17:23 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=976779, encodeId=278d9e677933, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210625/cdfaaa05402e44528b0355026d1ecc97/7ae8fb9c61da488fb9ab1d85bfdad744.jpg, createdBy=8cdb5533994, createdName=蓝色贝鱼88, createdTime=Fri Jun 25 13:12:38 CST 2021, time=2021-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=971302, encodeId=ac209e130282, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bd984965877, createdName=1453df99m58暂无昵称, createdTime=Sun Jun 06 15:27:52 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256089, encodeId=651d12560892f, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373526, encodeId=f5c113e3526c7, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sun Jun 06 01:40:15 CST 2021, time=2021-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970846, encodeId=82a99e084663, content=挺好的<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=169, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6e565513362, createdName=ms9000001913283834, createdTime=Fri Jun 04 11:28:00 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970834, encodeId=84049e0834eb, content=好用, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=31545513340, createdName=ms1000001134092964, createdTime=Fri Jun 04 11:01:09 CST 2021, time=2021-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=970828, encodeId=3e729e082847, content=科学性, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210604/719495b6f46e43bbbd0b0e6b82640536/303611f29cbf4ba389448a64928ffcb9.jpg, createdBy=013d1365052, createdName=dongquanhai, createdTime=Fri Jun 04 10:45:08 CST 2021, time=2021-06-04, status=1, ipAttribution=)]
    2021-06-04 ms1000001134092964

    好用

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1983722, encodeId=875b1983e223c, content=<a href='/topic/show?id=628553048e3' target=_blank style='color:#2F92EE;'>#患者死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53048, encryptionId=628553048e3, topicName=患者死亡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sun Sep 19 01:40:15 CST 2021, time=2021-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1006636, encodeId=b1f5100663629, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLyXfB3bOYOsDt885AsrYWhiaRtRdPh9aZlXugm7XErBVXusv5fJLIKWTicmjSQcOibDiaLzE2YMD44PA/132, createdBy=49f71976501, 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    2021-06-04 dongquanhai

    科学性

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