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非控制性哮喘治疗的CD6靶向抗体Itolizumab的Ib期临床试验正式开始

2019-07-11 Allan MedSci原创

Equillium是一家生物技术公司,近日CD6靶向抗体Itolizumab的Ib期临床试验(EQUIP)已正式开始,用于治疗不受控制的中度至重度哮喘患者。

Equillium是一家生物技术公司,近日CD6靶向抗体ItolizumabIb临床试验(EQUIP)已正式开始,用于治疗不受控制的中度至重度哮喘患者。

EQUIP Ib期研究的首席研究员,皇家墨尔本医院Jo Douglass教授说:尽管目前的标准疗法,包括支气管扩张剂和吸入皮质类固醇,能够控制患者症状,但在某些情况下许多患者仍然会出现症状。对于这种疾病的生物学复杂性,仍需要具有独特作用机制的新型靶向治疗方法,即无论嗜酸性粒细胞水平如何,药物都能在各种类型的哮喘中发挥作用。Itolizumab能够抑制不同效应T细胞亚型(包括Th2Th17),而这些亚型在哮喘的发病机制中起重要作用


原始出处:

http://www.firstwordpharma.com/node/1652278#axzz5tMRLVCBr

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    2019-07-21 snf701207
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    2019-09-05 bioon3
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    2020-02-04 amy0550
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