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BMC Gastroenterology: 幽门螺杆菌感染与中国人群结直肠腺瘤性息肉风险增加有关

2019-02-23 不详 MedSci原创

胃幽门螺杆菌与慢性胃炎,消化性溃疡病和胃恶性肿瘤有关。本研究旨在探讨胃幽门螺杆菌与结直肠腺瘤性息肉(CAP)在中国人群中的关系。

背景
幽门螺杆菌与慢性炎,消化性溃疡病和胃恶性肿瘤有关。本研究旨在探讨胃幽门螺杆菌与结直肠腺瘤性息肉(CAP)在中国人群中的关系。

方法
研究人员招募了中国石油化工股份有限公司中石化镇海炼化分公司的一千三百七十五名工人。给予所有参与者进行碳-13尿素呼吸试验,结肠直肠活检用于检测幽门螺杆菌和CAP。并确定CAP与幽门螺杆菌感染(HPI)的数量和分布之间的相关性。应用Logistic回归模型计算幽门螺旋杆菌对CAP风险的影响。

结果
180名参与者被诊断为CAP,1195名参与者被归类为健康对照。CAP组的HPI患病率显着高于健康对照组(57.8%VS40.1%)(p <0.001),即使在多个参数调整后,发现CAP的风险增加与幽门螺杆菌相关(OR = 3.237; 95.0%CI 2.184-4.798,p = 0.00)。Pathway studio分析表明,HPI在多层次上与CAP相连。

结论
HPI与中国人群中CAP风险增加有关。

原始出处:

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    2019-10-19 kcb069
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target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Oct 17 00:13:00 CST 2019, time=2019-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1348727, encodeId=74751348e2741, content=<a href='/topic/show?id=cfeb49103af' target=_blank style='color:#2F92EE;'>#幽门螺杆菌感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49103, encryptionId=cfeb49103af, topicName=幽门螺杆菌感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Mon Feb 25 08:13:00 CST 2019, time=2019-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1453223, encodeId=259614532234d, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Mon Feb 25 08:13:00 CST 2019, time=2019-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1504599, encodeId=23a9150459903, content=<a href='/topic/show?id=7730e85412' target=_blank style='color:#2F92EE;'>#Gastroenterology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7854, encryptionId=7730e85412, topicName=Gastroenterology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5fc29706655, createdName=chaojitidian, createdTime=Mon Feb 25 08:13:00 CST 2019, time=2019-02-25, status=1, ipAttribution=)]
    2019-05-16 许安
  5. 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  6. 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  7. 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  8. 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