Baidu
map

Spine :脊髓搏动超声示颈椎术后仰卧最利恢复

2014-04-23 佚名 丁香园

自1982年关于术中超声评估脊髓的首次报道以来,很多研究对脊髓搏动和搏动方式进行了探讨。关于颈椎病行椎板切除减压术后的脊髓情况的研究,也有为数不多的报道。然而,迄今为止,以经皮超声探讨颈椎板成型术后不同体位下脊髓搏动方式的变化和强度情况,尚未见报道。 日本弘前大学医学院骨科的学者进行了一项前瞻性队列研究,提示颈椎板成型术后不同体位下脊髓搏动强度不同,仰卧位更利于脊髓恢

自1982年关于术中超声评估脊髓的首次报道以来,很多研究对脊髓搏动和搏动方式进行了探讨。关于颈椎病行椎板切除减压术后的脊髓情况的研究,也有为数不多的报道。然而,迄今为止,以经皮超声探讨颈椎板成型术后不同体位下脊髓搏动方式的变化和强度情况,尚未见报道。

日本弘前大学医学院骨科的学者进行了一项前瞻性队列研究,提示颈椎板成型术后不同体位下脊髓搏动强度不同,仰卧位更利于脊髓恢复,文章于2014年4月发表在Spine上。

该回顾性病例分析共纳入33例行双开门颈椎板成型的病例,以超声评估仰卧、俯卧、端坐颈椎中立位、端坐颈椎前屈位及端坐颈椎后伸位的颈髓情况,评价指标包括脊髓搏动方式和强度,平均随访时间195天。



研究结果显示,不同体位下脊髓搏动的方式和强度、脊髓的前后位置均有变化。坐位时脊髓搏动最常见,仰卧位脊髓波动最常见。脊髓搏动强度,从高到低依次为仰卧、俯卧、端坐颈椎后伸位、端坐颈椎中立位及端坐颈椎前屈位。仰卧位蛛网膜下腔最为明显。

图2 颈椎板成型术后脊髓的超声图。图中小白箭头为脊髓,大黑箭头为椎体后壁,小黑箭头为蛛网膜下腔。

图3 三种不同类型的蛛网膜下腔。A非接触,蛛网膜下腔空间最大。B接触分离,B-1蛛网膜下腔消失,脊髓与椎体接触,B-2蛛网膜下腔重新出现。C完全接触,蛛网膜下腔空间小。

上述结果显示,考虑到好的脊髓搏动下脊髓的血供好,仰卧位时脊髓的张力小,腹侧的蛛网膜下腔最明显,对脊髓的恢复环境最为有利。

原始出处:

Kowatari K1, Nitobe T, Ono A, Tanaka T, Itabashi T, Ishibashi Y.Percutaneous ultrasonographic evaluation of the spinal cord after cervical laminoplasty.Spine (Phila Pa 1976). 2014 Apr 1;39(7):E434-40. doi: 10.1097/BRS.0000000000000209.


版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1699297, encodeId=050d169929e6d, content=<a href='/topic/show?id=f5821661e14' target=_blank style='color:#2F92EE;'>#Spine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16617, encryptionId=f5821661e14, topicName=Spine)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5829925263, createdName=mgqwxj, createdTime=Sat Nov 08 04:22:00 CST 2014, time=2014-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997578, encodeId=10c3199e578cd, content=<a href='/topic/show?id=c3e510060495' target=_blank style='color:#2F92EE;'>#颈椎术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100604, encryptionId=c3e510060495, topicName=颈椎术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=310e209, createdName=yzh399, createdTime=Thu Nov 13 04:22:00 CST 2014, time=2014-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9150, encodeId=7b82915059, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9151, encodeId=37a191511e, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9149, encodeId=4d99914959, content=学好英语先, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Fri Apr 25 13:04:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9148, encodeId=b77e9148ed, content=我要怎么才可能发文章呢? <br> <br> <br> www.hrgjk.com, beContent=null, objectType=article, channel=null, level=null, likeNumber=170, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 12:06:00 CST 2014, time=2014-04-25, status=1, ipAttribution=)]
    2014-11-08 mgqwxj
  2. [GetPortalCommentsPageByObjectIdResponse(id=1699297, encodeId=050d169929e6d, content=<a href='/topic/show?id=f5821661e14' target=_blank style='color:#2F92EE;'>#Spine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16617, encryptionId=f5821661e14, topicName=Spine)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5829925263, createdName=mgqwxj, createdTime=Sat Nov 08 04:22:00 CST 2014, time=2014-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997578, encodeId=10c3199e578cd, content=<a href='/topic/show?id=c3e510060495' target=_blank style='color:#2F92EE;'>#颈椎术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100604, encryptionId=c3e510060495, topicName=颈椎术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=310e209, createdName=yzh399, createdTime=Thu Nov 13 04:22:00 CST 2014, time=2014-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9150, encodeId=7b82915059, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9151, encodeId=37a191511e, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9149, encodeId=4d99914959, content=学好英语先, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Fri Apr 25 13:04:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9148, encodeId=b77e9148ed, content=我要怎么才可能发文章呢? <br> <br> <br> www.hrgjk.com, beContent=null, objectType=article, channel=null, level=null, likeNumber=170, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 12:06:00 CST 2014, time=2014-04-25, status=1, ipAttribution=)]
    2014-11-13 yzh399
  3. [GetPortalCommentsPageByObjectIdResponse(id=1699297, encodeId=050d169929e6d, content=<a href='/topic/show?id=f5821661e14' target=_blank style='color:#2F92EE;'>#Spine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16617, encryptionId=f5821661e14, topicName=Spine)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5829925263, createdName=mgqwxj, createdTime=Sat Nov 08 04:22:00 CST 2014, time=2014-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997578, encodeId=10c3199e578cd, content=<a href='/topic/show?id=c3e510060495' target=_blank style='color:#2F92EE;'>#颈椎术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100604, encryptionId=c3e510060495, topicName=颈椎术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=310e209, createdName=yzh399, createdTime=Thu Nov 13 04:22:00 CST 2014, time=2014-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9150, encodeId=7b82915059, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9151, encodeId=37a191511e, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9149, encodeId=4d99914959, content=学好英语先, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Fri Apr 25 13:04:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9148, encodeId=b77e9148ed, content=我要怎么才可能发文章呢? <br> <br> <br> www.hrgjk.com, beContent=null, objectType=article, channel=null, level=null, likeNumber=170, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 12:06:00 CST 2014, time=2014-04-25, status=1, ipAttribution=)]
    2014-04-25 doudou2014

    这和英语有啥关系呢?教一下贝

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1699297, encodeId=050d169929e6d, content=<a href='/topic/show?id=f5821661e14' target=_blank style='color:#2F92EE;'>#Spine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16617, encryptionId=f5821661e14, topicName=Spine)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5829925263, createdName=mgqwxj, createdTime=Sat Nov 08 04:22:00 CST 2014, time=2014-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997578, encodeId=10c3199e578cd, content=<a href='/topic/show?id=c3e510060495' target=_blank style='color:#2F92EE;'>#颈椎术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100604, encryptionId=c3e510060495, topicName=颈椎术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=310e209, createdName=yzh399, createdTime=Thu Nov 13 04:22:00 CST 2014, time=2014-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9150, encodeId=7b82915059, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9151, encodeId=37a191511e, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9149, encodeId=4d99914959, content=学好英语先, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Fri Apr 25 13:04:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9148, encodeId=b77e9148ed, content=我要怎么才可能发文章呢? <br> <br> <br> www.hrgjk.com, beContent=null, objectType=article, channel=null, level=null, likeNumber=170, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 12:06:00 CST 2014, time=2014-04-25, status=1, ipAttribution=)]
    2014-04-25 doudou2014

    这和英语有啥关系呢?教一下贝

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1699297, encodeId=050d169929e6d, content=<a href='/topic/show?id=f5821661e14' target=_blank style='color:#2F92EE;'>#Spine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16617, encryptionId=f5821661e14, topicName=Spine)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5829925263, createdName=mgqwxj, createdTime=Sat Nov 08 04:22:00 CST 2014, time=2014-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997578, encodeId=10c3199e578cd, content=<a href='/topic/show?id=c3e510060495' target=_blank style='color:#2F92EE;'>#颈椎术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100604, encryptionId=c3e510060495, topicName=颈椎术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=310e209, createdName=yzh399, createdTime=Thu Nov 13 04:22:00 CST 2014, time=2014-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9150, encodeId=7b82915059, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9151, encodeId=37a191511e, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9149, encodeId=4d99914959, content=学好英语先, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Fri Apr 25 13:04:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9148, encodeId=b77e9148ed, content=我要怎么才可能发文章呢? <br> <br> <br> www.hrgjk.com, beContent=null, objectType=article, channel=null, level=null, likeNumber=170, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 12:06:00 CST 2014, time=2014-04-25, status=1, ipAttribution=)]
    2014-04-25 匿名用户

    学好英语先

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1699297, encodeId=050d169929e6d, content=<a href='/topic/show?id=f5821661e14' target=_blank style='color:#2F92EE;'>#Spine#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16617, encryptionId=f5821661e14, topicName=Spine)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ba5829925263, createdName=mgqwxj, createdTime=Sat Nov 08 04:22:00 CST 2014, time=2014-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997578, encodeId=10c3199e578cd, content=<a href='/topic/show?id=c3e510060495' target=_blank style='color:#2F92EE;'>#颈椎术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100604, encryptionId=c3e510060495, topicName=颈椎术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=310e209, createdName=yzh399, createdTime=Thu Nov 13 04:22:00 CST 2014, time=2014-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9150, encodeId=7b82915059, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9151, encodeId=37a191511e, content=这和英语有啥关系呢?教一下贝, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 14:10:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9149, encodeId=4d99914959, content=学好英语先, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Fri Apr 25 13:04:00 CST 2014, time=2014-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=9148, encodeId=b77e9148ed, content=我要怎么才可能发文章呢? <br> <br> <br> www.hrgjk.com, beContent=null, objectType=article, channel=null, level=null, likeNumber=170, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fbd0101519, createdName=doudou2014, createdTime=Fri Apr 25 12:06:00 CST 2014, time=2014-04-25, status=1, ipAttribution=)]
    2014-04-25 doudou2014

    我要怎么才可能发文章呢?


    www.hrgjk.com

    0

相关资讯

Spine:10秒踏步试验可评价脊髓压迫程度

  脊髓压迫症(Compressive Myelopathy)是一组由椎管内占位性病变所引起的脊髓受压综合征,可导致脊髓或脊神经功能障碍。脊髓压迫症的常见病因主要包括肿瘤、强直性脊柱炎、椎间盘突出、黄韧带骨化症、后纵韧带骨化等。   随着病变的不断进展,脊髓、脊神经根及其供应血管受压日益严重,一旦超过代偿能力,最终会造成脊髓水肿、变性、坏死等病理变化,出现脊髓半切或横贯性损害及椎管梗阻,

AAOS 2014:微损伤是快速恶化颈脊髓病的病理生理基础

脊髓型颈椎病(Cervical spondylotic myelopathy ,CSM)是发展相对较慢的一种疾病,在临床工作中脊髓型颈椎病由颈脊髓病变开始快速恶化的情况比较少见,这可能是因为常规的脊髓型颈椎病与快速恶化的颈脊髓病变的病理生理存在一定的差异。很多研究已报道过CSM的发病机理。然而,关于快速加重恶化的脊髓型颈椎病的详细情况的相关研究却很少。此回顾性临床研究的目的

Nat Commun:硫酸软骨素让受伤的脊髓更好恢复

硫酸软骨素(神经系统瘢痕的一个成分)的生物合成所需的一种酶的去除,使得小鼠在脊髓受伤后运动功能得到更好恢复。本期Nature Communications上发表的一篇论文所报告的这项研究加强了我们对脊髓受伤后恢复的认识,同时也可能为这种受伤后的治疗指出了一个新目标。 蛋白多糖是胶质瘢痕的成分,这种瘢痕是脊髓受伤后形成的,其作用是帮助中枢神系统愈合,但也阻止神经元的再生长。用软骨素酶(降解蛋白多糖

Baidu
map
Baidu
map
Baidu
map