Baidu
map

心血管

订阅

MedSci主页 / 所有栏目 / 心血管

SCI REP：中国农村人群静息心率和脉压对2型糖尿病的独立和累积效应影响！

2017-06-02 xing.T MedSci原创

RHRPPT2DM
关注

这项研究表明，升高的RHR和PP各自独立地与T2DM的风险相关，也影响了传统的混杂因素，RHR较快PP较高可能累积地增加T2DM的风险。然而，潜在的临床应用仍有待进一步明确。

近日，Scientific reports 杂志上发表了一篇研究文章，研究人员旨在通过横断面研究和荟萃分析来探讨静息心率（RHR）和脉压（PP）对2型糖尿病（T2DM）风险的独立效应以及它们的累积效应。

该研究共纳入了8276名来自于农村糖尿病、肥胖和生活方式研究（RuralDiab研究）中的年龄在35岁至74岁的受试者。同时，进行了两项荟萃分析以验证流行病学研究的结果。

研究人员发现RHR和PP与T2DM的风险增高有关，而每个四分位数相应的调整后比值比（95%可信区间）分别为1.0、0.99（0.68-1.42）、1.58（1.13-2.20）、2.93（2.15–3.98）和1、1.06（0.75-1.48）、1.11（0.79-1.56）、1.45（1.03-2.03）。累积效应分析表明相比于缓慢RHR低PP人群、男性、女性，快速RHR高PP受试者调整后的比值比（95%可信区间）在分别为3.36（2.26-4.99）、2.60（1.47-4.59）和3.60（2.09-6.20）。Meta分析结果显示RHR和PP合并效应值分别为1.94（1.64-2.31）和1.25（1.04-1.51）。

这项研究表明，升高的RHR和PP各自独立地与T2DM的风险相关，也影响了传统的混杂因素，RHR较快PP较高可能累积地增加T2DM的风险。然而，潜在的临床应用仍有待进一步明确。

原始出处：

Panpan Wang,et al. Independent and cumulative effects of resting heart rate and pulse pressure with type 2 diabetes mellitus in Chinese rural population. Scientific reports. 2017. https://www.nature.com/articles/s41598-017-02758-1

本文系梅斯医学（MedSci）原创编译整理，转载需授权！


版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1804425, encodeId=0933180442578, content=<a href='/topic/show?id=c754e7083a8' target=_blank style='color:#2F92EE;'>#累积效应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77083, encryptionId=c754e7083a8, topicName=累积效应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=570c172, createdName=tigerlr98, createdTime=Tue Apr 17 13:57:00 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1404998, encodeId=dc7d140499813, content=<a href='/topic/show?id=2c4a30e76c7' target=_blank style='color:#2F92EE;'>#农村#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30776, encryptionId=2c4a30e76c7, topicName=农村)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b76a2518787, createdName=daviiliu, createdTime=Sun Jun 04 00:57:00 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579023, encodeId=760615e90230a, content=<a href='/topic/show?id=3007990e6f0' target=_blank style='color:#2F92EE;'>#静息心率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99076, encryptionId=3007990e6f0, topicName=静息心率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=692416492771, createdName=12498761m61暂无昵称, createdTime=Sun Jun 04 00:57:00 CST 2017, time=2017-06-04, status=1, ipAttribution=)]
    2018-04-17 tigerlr98

    #累积效应#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1804425, encodeId=0933180442578, content=<a href='/topic/show?id=c754e7083a8' target=_blank style='color:#2F92EE;'>#累积效应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77083, encryptionId=c754e7083a8, topicName=累积效应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=570c172, createdName=tigerlr98, createdTime=Tue Apr 17 13:57:00 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1404998, encodeId=dc7d140499813, content=<a href='/topic/show?id=2c4a30e76c7' target=_blank style='color:#2F92EE;'>#农村#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30776, encryptionId=2c4a30e76c7, topicName=农村)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b76a2518787, createdName=daviiliu, createdTime=Sun Jun 04 00:57:00 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579023, encodeId=760615e90230a, content=<a href='/topic/show?id=3007990e6f0' target=_blank style='color:#2F92EE;'>#静息心率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99076, encryptionId=3007990e6f0, topicName=静息心率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=692416492771, createdName=12498761m61暂无昵称, createdTime=Sun Jun 04 00:57:00 CST 2017, time=2017-06-04, status=1, ipAttribution=)]
    2017-06-04 daviiliu

    #农村#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1804425, encodeId=0933180442578, content=<a href='/topic/show?id=c754e7083a8' target=_blank style='color:#2F92EE;'>#累积效应#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77083, encryptionId=c754e7083a8, topicName=累积效应)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=570c172, createdName=tigerlr98, createdTime=Tue Apr 17 13:57:00 CST 2018, time=2018-04-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1404998, encodeId=dc7d140499813, content=<a href='/topic/show?id=2c4a30e76c7' target=_blank style='color:#2F92EE;'>#农村#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30776, encryptionId=2c4a30e76c7, topicName=农村)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b76a2518787, createdName=daviiliu, createdTime=Sun Jun 04 00:57:00 CST 2017, time=2017-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579023, encodeId=760615e90230a, content=<a href='/topic/show?id=3007990e6f0' target=_blank style='color:#2F92EE;'>#静息心率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99076, encryptionId=3007990e6f0, topicName=静息心率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=692416492771, createdName=12498761m61暂无昵称, createdTime=Sun Jun 04 00:57:00 CST 2017, time=2017-06-04, status=1, ipAttribution=)]
    2017-06-04 12498761m61暂无昵称

    #静息心率#

    0

Baidu
map
Baidu
map
Baidu
map