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BMJ：甲床鳞状细胞癌案例报道

2015-12-03 Mechront 译 MedSci原创

甲床甲沟炎鳞状细胞癌
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75岁老年男性，疑似右手食指甲沟炎4个月，使用抗生素和抗真菌治疗无效。X线平片：远端指骨的破坏。提示骨髓炎。外科手术发现边界清晰的指甲下肿块，活检证实为：甲床中度分化鳞状细胞癌（不伴感染）。尽管是什么原因导致的甲床鳞状细胞癌仍不清楚，但是是甲床常见的原发性肿瘤。该疾病很少出现转移，也没有发现过淋巴结病变。为清除肿瘤病灶，该患者经中间指骨行了截肢。要点：1.指甲下的鳞状细胞癌与很多良性病变表现类似，

75岁老年男性，疑似右手食指甲沟炎4个月，使用抗生素和抗真菌治疗无效。X线平片：远端指骨的破坏。提示骨髓炎。


外科手术发现边界清晰的指甲下肿块，活检证实为：甲床中度分化鳞状细胞癌（不伴感染）。

尽管是什么原因导致的甲床鳞状细胞癌仍不清楚，但是是甲床常见的原发性肿瘤。该疾病很少出现转移，也没有发现过淋巴结病变。为清除肿瘤病灶，该患者经中间指骨行截肢。

要点：

1.指甲下的鳞状细胞癌与很多良性病变表现类似，在非典型症状体征的时候应对鳞癌保持怀疑。

2.建议通过多学科的方法来评估、管理和跟踪这些病变。

3.如果怀疑任何骨或软组织肿瘤，应与三级转诊医院讨论或进行转诊治疗。

原始出处：

Nicholls A, Jacoby J,et al.Squamous cell carcinoma of the nail bed.BMJ. 2015 Sep 2

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    2017-09-15 133200d54bm

    好文章

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=244418, encodeId=5c962444181d, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c7f2150524, createdName=133200d54bm, createdTime=Fri Sep 15 23:29:13 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847786, encodeId=2975184e78629, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Aug 01 16:57:00 CST 2016, time=2016-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978428, encodeId=17d919e84286c, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Tue Apr 19 16:57:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49063, encodeId=1ee34906395, content=好文章，值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:00:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49064, encodeId=80d149064c9, content=好文章，值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:00:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45317, encodeId=b0a14531ea2, content=见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150714/IMG55A4BC357ED6E1444.jpg, createdBy=9f231612624, createdName=liushui8012, createdTime=Wed Dec 09 09:02:00 CST 2015, time=2015-12-09, status=1, ipAttribution=)]
    2016-08-01 gaoxiaoe

    #BMJ#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=244418, encodeId=5c962444181d, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c7f2150524, createdName=133200d54bm, createdTime=Fri Sep 15 23:29:13 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847786, encodeId=2975184e78629, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Aug 01 16:57:00 CST 2016, time=2016-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1978428, encodeId=17d919e84286c, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Tue Apr 19 16:57:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49063, encodeId=1ee34906395, content=好文章，值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:00:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=49064, encodeId=80d149064c9, content=好文章，值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=171, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 09:00:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45317, encodeId=b0a14531ea2, content=见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150714/IMG55A4BC357ED6E1444.jpg, createdBy=9f231612624, createdName=liushui8012, createdTime=Wed Dec 09 09:02:00 CST 2015, time=2015-12-09, status=1, ipAttribution=)]
    2016-04-19 qingting

    #细胞癌#

    0

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    2015-12-27 hixiaoluo

    好文章，值得收藏

    0

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    2015-12-27 hixiaoluo

    好文章，值得收藏

    0

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    2015-12-09 liushui8012

    见识了

    0

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