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Circulation:预防心血管病应从娃娃抓起(STRIP研究)

2015-02-17 MedSci 中国循环杂志

芬兰一项名为STRIP的纵向随机研究显示,若从婴儿时期就通过学校或父母对其实施健康饮食生活计划,则在其15~20 岁时,患代谢综合征风险将下降41%。 研究纳入1062例婴幼儿,分为饮食生活干预组和不干预组。在干预组实施限盐计划,并推荐全谷物、水果及蔬菜饮食,并在其8岁后,对其初步普及戒烟知识并鼓励多进行体力活动。 在受试者15~20岁时,干预组代谢综合征患病率为 6.0%


芬兰一项名为STRIP的纵向随机研究显示,若从婴儿时期就通过学校或父母对其实施健康饮食生活计划,则在其15~20 岁时,患代谢综合征风险将下降41%。

研究纳入1062例婴幼儿,分为饮食生活干预组和不干预组。在干预组实施限盐计划,并推荐全谷物、水果及蔬菜饮食,并在其8岁后,对其初步普及戒烟知识并鼓励多进行体力活动。

在受试者15~20岁时,干预组代谢综合征患病率为 6.0%~7.5%,对照组患病率为 10%~14%。干预组患代谢综合征长期风险显著下降,且其高血压以及男性高甘油三酯的患病率也显著下降。

对此,研究者指出,婴幼儿期是最具可塑性的阶段,在此期间进行干预最有可能留下心血管终生健康的轨迹,而之后即使在儿童后期或青少年期间进行干预,可能也难以达到这样的效果。因此,要想终生预防心血管病,就应在婴幼儿时期进行相关预防。

原始出处:
Nupponen M, Pahkala K, Juonala M, Magnussen CG, Niinikoski H, Rönnemaa T, Viikari JS, Saarinen M, Lagström H, Jula A, Simell O, Raitakari OT.Metabolic Syndrome from Adolescence to Early Adulthood: Effect of Infancy-Onset Dietary Counseling of Low-Saturated-Fat: The Special Turku Coronary Risk Factor Intervention Project (STRIP). Circulation. 2015 Jan 20. pii: CIRCULATIONAHA.114.010532

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1644430, encodeId=609d164443044, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Tue Mar 24 16:19:00 CST 2015, time=2015-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16879, encodeId=9c7b168e907, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Tue Feb 24 11:18:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16491, encodeId=8b421649118, content=呵呵, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef1a1612671, createdName=drhqh240, createdTime=Thu Feb 19 18:20:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16382, encodeId=35bd1638244, content=请注明出处!, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=101.26.186.**, createdTime=Wed Feb 18 17:44:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16345, encodeId=62191634516, content=怎么实施, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 06:58:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16334, encodeId=4b42163344b, content=在受试者15~20岁时,干预组代谢综合征患病率为 6.0%~7.5%,对照组患病率为 10%~14%。比例有如此之高?, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Tue Feb 17 23:08:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16321, encodeId=31fa16321cf, content=表面有理,关键如何实施?, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=49.4.167.**, createdTime=Tue Feb 17 22:55:00 CST 2015, time=2015-02-17, status=1, ipAttribution=)]
    2015-02-24 orthoW

    不错的文章,学习了

    0

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    2015-02-19 drhqh240

    呵呵

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1644430, encodeId=609d164443044, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Tue Mar 24 16:19:00 CST 2015, time=2015-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16879, encodeId=9c7b168e907, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Tue Feb 24 11:18:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16491, encodeId=8b421649118, content=呵呵, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef1a1612671, createdName=drhqh240, createdTime=Thu Feb 19 18:20:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16382, encodeId=35bd1638244, content=请注明出处!, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=101.26.186.**, createdTime=Wed Feb 18 17:44:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16345, encodeId=62191634516, content=怎么实施, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 06:58:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16334, encodeId=4b42163344b, content=在受试者15~20岁时,干预组代谢综合征患病率为 6.0%~7.5%,对照组患病率为 10%~14%。比例有如此之高?, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Tue Feb 17 23:08:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16321, encodeId=31fa16321cf, content=表面有理,关键如何实施?, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=49.4.167.**, createdTime=Tue Feb 17 22:55:00 CST 2015, time=2015-02-17, status=1, ipAttribution=)]
    2015-02-18 101.26.186.**

    请注明出处!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1644430, encodeId=609d164443044, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Tue Mar 24 16:19:00 CST 2015, time=2015-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16879, encodeId=9c7b168e907, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Tue Feb 24 11:18:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16491, encodeId=8b421649118, content=呵呵, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef1a1612671, createdName=drhqh240, createdTime=Thu Feb 19 18:20:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16382, encodeId=35bd1638244, content=请注明出处!, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=101.26.186.**, createdTime=Wed Feb 18 17:44:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16345, encodeId=62191634516, content=怎么实施, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 06:58:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16334, encodeId=4b42163344b, content=在受试者15~20岁时,干预组代谢综合征患病率为 6.0%~7.5%,对照组患病率为 10%~14%。比例有如此之高?, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Tue Feb 17 23:08:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16321, encodeId=31fa16321cf, content=表面有理,关键如何实施?, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=49.4.167.**, createdTime=Tue Feb 17 22:55:00 CST 2015, time=2015-02-17, status=1, ipAttribution=)]
    2015-02-18 午夜星河

    怎么实施

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1644430, encodeId=609d164443044, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Tue Mar 24 16:19:00 CST 2015, time=2015-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16879, encodeId=9c7b168e907, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Tue Feb 24 11:18:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16491, encodeId=8b421649118, content=呵呵, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef1a1612671, createdName=drhqh240, createdTime=Thu Feb 19 18:20:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16382, encodeId=35bd1638244, content=请注明出处!, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=101.26.186.**, createdTime=Wed Feb 18 17:44:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16345, encodeId=62191634516, content=怎么实施, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 06:58:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16334, encodeId=4b42163344b, content=在受试者15~20岁时,干预组代谢综合征患病率为 6.0%~7.5%,对照组患病率为 10%~14%。比例有如此之高?, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Tue Feb 17 23:08:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16321, encodeId=31fa16321cf, content=表面有理,关键如何实施?, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=49.4.167.**, createdTime=Tue Feb 17 22:55:00 CST 2015, time=2015-02-17, status=1, ipAttribution=)]
    2015-02-17 medcardio

    在受试者15~20岁时,干预组代谢综合征患病率为 6.0%~7.5%,对照组患病率为 10%~14%。比例有如此之高?

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1644430, encodeId=609d164443044, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Tue Mar 24 16:19:00 CST 2015, time=2015-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16879, encodeId=9c7b168e907, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Tue Feb 24 11:18:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16491, encodeId=8b421649118, content=呵呵, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ef1a1612671, createdName=drhqh240, createdTime=Thu Feb 19 18:20:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16382, encodeId=35bd1638244, content=请注明出处!, beContent=null, objectType=article, channel=null, level=null, likeNumber=159, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=101.26.186.**, createdTime=Wed Feb 18 17:44:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16345, encodeId=62191634516, content=怎么实施, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 06:58:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16334, encodeId=4b42163344b, content=在受试者15~20岁时,干预组代谢综合征患病率为 6.0%~7.5%,对照组患病率为 10%~14%。比例有如此之高?, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Tue Feb 17 23:08:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16321, encodeId=31fa16321cf, content=表面有理,关键如何实施?, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=49.4.167.**, createdTime=Tue Feb 17 22:55:00 CST 2015, time=2015-02-17, status=1, ipAttribution=)]
    2015-02-17 49.4.167.**

    表面有理,关键如何实施?

    0

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