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JAMA Neurol:老年人群中风的致残风险显著高于心梗致残风险

2017-10-24 zhangfan MedSci原创

研究认为,中风相对于心梗对老年人群的损伤更为严重,缺血性中风导致的大脑功能衰退与老年人致残致死率增加有着密切的关系

一般认为老年人群的常见病--缺血性中风和心肌梗死会加速人体机能的衰退。近日研究人员开展研究旨在比较缺血性脑卒中和心梗前后机体机能衰退或致残的速率差异。

本次研究是以人群为基础的前瞻性队列心血管健康研究(1989-2013),平均随访13年,采用广义估计方程的模型,评估中风事件机体衰退速率差异。研究招募了5888名65岁以上参与者,研究的主要终点是每年的日常生活活动致残评估(ADLs).

参与者进组平均年龄72.8岁,男性2495人,占42.4%。随访期间发生了382例(6.5%)中风事件和395起(6.7%)心肌梗死。在中风前后3.7年以及心梗前后3.8年对患者进行随访。研究发现,中风对患者致残效果更为显著(致残评分,中风0.88分vs心梗0.2分)。患者中风前,年致残得分增加0.06分,中风后增长至年0.15分;心梗前年致残得分为0.04分,心梗后为年0.02分。

研究认为,中风相对于心梗对老年人群的损伤更为严重,缺血性中风导致的大脑功能衰退与老年人致残致死率增加有着密切的关系。

原始出处:


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    2018-08-03 yinhl1978
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    2017-10-24 天涯183

    非常好的文章.学习了

    0

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