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Hypertension:子痫前期对女性患心血管并发症和下次妊娠的影响

2016-02-23 QQduhp 译 MedSci原创

多次患有妊娠相关高血压且妊娠间期出现的可识别心脏功能异常有助于预测女性下次妊娠及今后生活中出现的心脏和血管疾病的风险,这项研究发表在Hypertension。妊娠相关高血压或子痫前期是一种严重的疾病,约3%-8%的孕妇会出现。若女性在孕32周前出现子痫前期则为子痫前期早期。子痫前期对母婴皆有不利影响。Herbert Valensise教授指出,女性若在首次妊娠时出现子痫前期早期则应了解其风险,并在

多次患有妊娠相关高血压且妊娠期间出现可识别的心脏功能异常有助于预测女性下次妊娠及今后生活中出现的心脏和血管疾病的风险,这项研究发表在Hypertension


妊娠相关高血压或子痫前期是一种严重的疾病,约3%-8%的孕妇会出现。若女性在孕32周前出现子痫前期则为子痫前期早期。子痫前期对母婴皆有不利影响。Herbert Valensise教授指出,女性若在首次妊娠时出现子痫前期早期则应了解其风险,并在以后的生活中多加注意。

研究表明,出现子痫前期的女性在今后怀孕中出现子痫前期及心血管疾病的风险是妊娠正常女性的7倍。

在这项研究中,参与者为75名患有子痫前期的女性和147名未患该病的女性。研究初始时没有参与者怀孕,所有参与者在首次分娩12-18月后接受了心脏成像检查。所有的参与者在24个月内再次怀孕,研究人员对她们进行了持续的随访调查直至孕晚期。在出现子痫前期的75名女性中有22名女性(29%)再次患子痫前期。参与者的平均年龄为34岁。 

研究人员发现,首次罹患子痫前期并在随后妊娠中再次患子痫前期的女性在怀孕前心脏四腔中有某一腔存在异常。她们的左心室功能出现了异常。 

Valensise指出,医生必须充分认识到子痫前期对女性患心血管并发症和下次妊娠的影响,当医生询问女性一些危险因素如吸烟、高胆固醇、心血管疾病家族史后,还应该询问是否患孕期高血压,尤其是子痫前期早期。

原始出处:

Roberts JM, Mascalzoni D, Ness RB, Poston L.Collaboration to Understand Complex Diseases: Preeclampsia and Adverse Pregnancy Outcomes.Hypertension. 2016 Feb 16.

 

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    2016-07-09 丁鹏鹏
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    2016-09-30 feather89
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    2016-02-25 yahu
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