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外媒:发烧是好事儿 或可破解当今不治之症

2016-01-25 佚名 参考消息

参考消息网1月22日报道西媒称,引起发烧的免疫反应可能同时也激活了神经系统,体温升高可能有助于治疗自闭症和癌症。 西班牙《万象》月刊12月号刊载题为《发烧是好事儿》的文章,提到富豪级的数学家詹姆斯·西蒙的亲身经历。这位父亲有一位患有自闭症的女儿。通过一段时间的观察他发现,每当女儿发烧时,她与外界的沟通似乎更加顺畅,而自闭症特有的一些病理性的疯狂举止似乎也有所减轻。于是,西蒙发起成立了一家

参考消息网1月22日报道西媒称,引起发烧的免疫反应可能同时也激活了神经系统,体温升高可能有助于治疗自闭症和癌症。

西班牙《万象》月刊12月号刊载题为《发烧是好事儿》的文章,提到富豪级的数学家詹姆斯·西蒙的亲身经历。这位父亲有一位患有自闭症的女儿。通过一段时间的观察他发现,每当女儿发烧时,她与外界的沟通似乎更加顺畅,而自闭症特有的一些病理性的疯狂举止似乎也有所减轻。于是,西蒙发起成立了一家基金会,专门研究为何出现这种变化,以及能否利用这一现象作为未来治疗自闭症的一种途径。2007年,约翰斯·霍普金斯-布隆伯格公共卫生学院的流行病学家小组取得了最初成果。他们发表的研究报告证实,发烧可以缓解自闭症症状。但是,为什么呢?

让我们发烧

报道称,美国洛克菲勒大学分子生物学实验室的西班牙籍研究员玛丽安·梅勒也参与了詹姆斯·西蒙的基金会所资助的研究项目。她认为,“发烧是一种防御机制,是在体内有病原体出现时免疫系统开始活动的反映。我们因此认为,发烧与行为改变之间的关系恰恰反映出了免疫系统与神经系统之间确实存在关联。所以,引起发烧的免疫系统应答过程也可能刺激或抑制因自闭症而改变的神经系统的某些区域。这就是自闭症患者出现暂时性行为特征转变的原因”。

梅勒还提到,“我们还认为大脑的某些区域负责对体温做出响应,同时也和负责调节与自闭症相关行为的大脑区域相互有联系。因此,这些区域被暂时激活可能会导致涉及焦虑、社交行为、暴躁和语言等领域的神经元活动发生改变。同时也可能存在一种后生效应,导致与某些神经元活动相关的基因被激活或被抑制”。

报道称,不管原因是什么,发烧有益于自闭症症状缓解这一点已是确凿无疑的。甚至将来有一天可以将发烧作为一种“处方”,人为地让自闭症患者保持高体温。

高温抗癌

报道称,癌症药物治疗的最新趋势是借助免疫疗法,即采取措施激活免疫系统来对抗癌细胞。西班牙纳瓦拉大学和应用医学研究中心免疫疗法专家伊格纳西奥·梅莱罗表示,“肿瘤出现时表明,它有能力戏弄免疫系统。借助免疫疗法的各种手段,我们追求的目标是训练免疫系统发挥作用,以人为的方式告诉它如何识别和破坏癌细胞”。发烧就是人体免疫系统的一部分。

梅莱罗认为,利用发烧作为引线的治疗方法被称为热疗,也就是给麻醉状态下的患者预热体温,模拟出一种持续高烧的症状。但是,这种做法却具有风险,时至今日还没有研究出一种有效的方法。如果能够结合其他更加有效的免疫疗法,或许它就具有意义了。

另一方面,医学界最近还发现一些慢性病,如抑郁和焦虑都会导致人体体温升高。

心理疗法

报道称,2014年,京都大学的科学家确认了与抑郁导致的体温升高有关的神经回路。该神经回路连接着下丘脑背内侧核与延髓中缝核。研究人员说:“了解这一机制对于理解心因性发热的发展方式以及制订治疗方案都非常重要。”

51岁的独居妇女卡门平日过着相对健康的生活。但从几个月前起她开始频繁发烧,并且来得快,去得也快,且没有更多的身体衰弱症状。在接受了各种检查后,医生诊断她患上了“心因性发热”。原因呢?4个月前,原本跟她住得非常近的姐姐一家搬到了很远的大房子居住,只能每逢周末才回来看望她。现在,她每天只能按部就班地到那个已经供职了20多年的小公司,继续做秘书工作。经过了心理药物治疗后,卡门的发烧现象消失了。

报道称,卡门的例子确确实实存在,而且在医学上也能找到更合理的解释。抑郁不过是在我们感知到周遭的威胁或发生了超出我们能力范围的事情之时,出现的一种心理过程。

在这种情况下,我们的身体准备好要么应对危险,要么“逃跑”,造成的结果就是呼吸和心跳频率加快,体温也随之升高。这就是抑郁导致的体温过高。但是,95%的发烧病例不过就是我们的身体器官对病原体产生的反应。

儿科专家郝苏斯·马丁内斯认为,“以前如果身体感觉难受,体温升高,会被认为是身体器官对病菌产生的反应,因此发烧被看做是身体防御系统发挥作用的指征,患者处于康复过程中。直到后来,我们开始可以借助体温计测量体温,发烧就变成了我们看到的主要身体表现”。

痴迷于体温

报道称,2014年,全世界各国的儿科协会达成一致,想办法抵制对发烧的病态“恐惧”,尤其是大多数父母对发烧的看法。

《美国儿科疾病杂志》月刊发表了一项研究报告对这种普遍心态发出了警告。报告表示,大多数父母对38摄氏度以下的发烧有些过度担心。很多人都担心孩子体温升高可能会给身体造成可怕的后果,甚至有52%的父母认为如果发烧至40摄氏度,小孩儿就有可能出现严重的神经性紊乱。

马丁内斯指出,“责任肯定在我们。事实上,当父母带着孩子跑到急诊就医的时候,他们首先看的是怎么给孩子测体温。因此无形中我们传达的信息就是体温是第一位的,其他症状都是次要”。

然而,恰恰相反。“体温升高的时候,我们的身体感觉很难受,其实病菌也一样。因此,我们的身体升高了温度,以便让病原菌在攻击我们的时候也感觉不那么舒服,它们也就不能再继续繁殖。然而,一贯认为自己比身体更聪明的我们却用退热药物来降低体温,这样做其实并不会让温度降低,我们原本应该做的就是缓解症状,比如头痛和眩晕等”。

报道称,自从英国医生克利福德·奥尔伯特发明了第一支医学用体温计以来,这种工具已经变成了现代医学的符号,成为家家户户必备的最常见的医用器械。但是,马丁内斯指出,“体温计只是测量体温的一种工具,而体温往往在外部环境和各种可变因素的影响下发生变化,这种可变因素包括穿着衣服的多少。因此,我们必须关注的是症状,而不是体温”。

增强免疫

报道称,美国过敏和传染病研究所发表的一篇研究报告称,发烧的好处非常多,比如出生头一年经历过发烧过程的新生儿比那些没有发过烧的新生儿,在幼年时期患过敏的几率大大降低。医学界已经形成了一个普遍观点,早期接触感染可以保护人体免受过敏的困扰。但是,马丁内斯也提出了一种令人担心的特殊可能性:“对于3个月的新生儿来说,他们的颅脑屏障还十分脆弱。在这种情况下,任何感染都有可能变成脓血症或脑膜炎。这是非常严重的事情。因此,新生儿父母对38摄氏度以上的发烧一定要提高警惕,体温一旦超过38度,应该尽早到急诊就医,以便尽早对抗感染”。

1660年,英国医生托马斯·西德纳姆写道:“发烧是大自然赐予世界的一部强大的引擎,用它来征服敌人。”然而,我们现在所了解到的是,西德纳姆所言不仅是真实的,而且在很多情况下,高体温还能成为一种有力的武器,让我们可以有效地杀死致命敌人。

好吧,祝福发烧吧!(编译/王萌)(原标题:外媒:发烧是好事儿或可破解当今不治之症)

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    2016-03-21 忠诚向上

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    2016-03-21 忠诚向上

    继续了解

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=72216, encodeId=5c9de221681, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72215, encodeId=9f39e22154b, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72214, encodeId=106ee2214db, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72208, encodeId=0ab5e220823, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72209, encodeId=dc11e22094f, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72210, encodeId=0387e22104e, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72211, encodeId=aec3e221170, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72212, encodeId=e8a0e2212e1, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=183, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72213, encodeId=bc97e22136d, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72206, encodeId=fd41e220683, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:20:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-21 忠诚向上

    继续了解

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=72216, encodeId=5c9de221681, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72215, encodeId=9f39e22154b, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72214, encodeId=106ee2214db, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72208, encodeId=0ab5e220823, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72209, encodeId=dc11e22094f, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72210, encodeId=0387e22104e, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72211, encodeId=aec3e221170, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72212, encodeId=e8a0e2212e1, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=183, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72213, encodeId=bc97e22136d, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72206, encodeId=fd41e220683, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:20:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-21 忠诚向上

    继续了解

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=72216, encodeId=5c9de221681, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72215, encodeId=9f39e22154b, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72214, encodeId=106ee2214db, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72208, encodeId=0ab5e220823, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72209, encodeId=dc11e22094f, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72210, encodeId=0387e22104e, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72211, encodeId=aec3e221170, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72212, encodeId=e8a0e2212e1, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=183, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72213, encodeId=bc97e22136d, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72206, encodeId=fd41e220683, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:20:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-21 忠诚向上

    继续了解

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=72216, encodeId=5c9de221681, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72215, encodeId=9f39e22154b, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72214, encodeId=106ee2214db, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72208, encodeId=0ab5e220823, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72209, encodeId=dc11e22094f, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72210, encodeId=0387e22104e, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72211, encodeId=aec3e221170, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72212, encodeId=e8a0e2212e1, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=183, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72213, encodeId=bc97e22136d, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72206, encodeId=fd41e220683, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:20:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-21 忠诚向上

    继续了解

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=72216, encodeId=5c9de221681, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72215, encodeId=9f39e22154b, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72214, encodeId=106ee2214db, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72208, encodeId=0ab5e220823, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72209, encodeId=dc11e22094f, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72210, encodeId=0387e22104e, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72211, encodeId=aec3e221170, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72212, encodeId=e8a0e2212e1, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=183, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72213, encodeId=bc97e22136d, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72206, encodeId=fd41e220683, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:20:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-21 忠诚向上

    继续了解

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=72216, encodeId=5c9de221681, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72215, encodeId=9f39e22154b, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72214, encodeId=106ee2214db, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72208, encodeId=0ab5e220823, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72209, encodeId=dc11e22094f, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72210, encodeId=0387e22104e, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72211, encodeId=aec3e221170, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72212, encodeId=e8a0e2212e1, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=183, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72213, encodeId=bc97e22136d, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72206, encodeId=fd41e220683, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:20:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-21 忠诚向上

    继续了解

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=72216, encodeId=5c9de221681, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72215, encodeId=9f39e22154b, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72214, encodeId=106ee2214db, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72208, encodeId=0ab5e220823, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72209, encodeId=dc11e22094f, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=155, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72210, encodeId=0387e22104e, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=199, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72211, encodeId=aec3e221170, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72212, encodeId=e8a0e2212e1, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=183, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72213, encodeId=bc97e22136d, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:21:00 CST 2016, time=2016-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72206, encodeId=fd41e220683, content=继续了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Mon Mar 21 18:20:00 CST 2016, time=2016-03-21, status=1, ipAttribution=)]
    2016-03-21 忠诚向上

    继续了解

    0

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    2016-03-21 忠诚向上

    继续了解

    0

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