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JAMA子刊:中耳胆脂瘤的发病部位及发病率

2016-01-08 QQduhp 译 MedSci原创

背景目前国际上针对胆脂瘤的分类标准有好几个,但是它们仍然有一定的争议。 目的该研究的目的在于明确胆脂瘤的分类并分析其发病率。 设计该研究为横向比较研究,研究对象为356名中耳胆脂瘤患者的414只耳朵。患者在2000-3-8到2015-3-30之间没有在三甲医院耳病手术及就诊史。研究人员使用内窥镜对患者的耳朵进行检查,并记录下相关结果,并在在2014-3-30到2015-3-30之间进行了数据分析。

背景:目前国际上针对胆脂瘤的分类标准有好几个,但是它们仍然有一定的争议。
 
目的:该研究的目的在于明确胆脂瘤的分类并分析其发病率。
 
设计:该研究为横断面的对比研究,研究对象为356名中耳胆脂瘤患者的414只耳朵。患者在2000-3-8到2015-3-30之间没有在三甲医院耳病手术及就诊史。研究人员使用内窥镜对患者的耳朵进行检查,并记录下相关结果,并在2014-3-30到2015-3-30之间进行了数据分析。 

主要结果和措施:胆脂瘤生长方式可分为上鼓室前、上鼓室后、中鼓室后、双向发展(包括鼓膜松弛部及鼓膜紧张部参与)和不明部位。

结果:356名参与者的平均年龄(SD)为33.23(19.81)岁,年龄范围为4-82 岁,其中125名参与者(35.1%)为女性。已经确定220名参与者(61.8%)的右耳受到影响,且研究对象的272只耳朵(65.7%)来自成人。研究人员发现,通过使用内窥镜对研究对象的414只耳朵进行检查后,可观察到耳胆脂瘤存在的部位最常见于上鼓室后(142只[34.3%])、 中鼓室后(140只[33.8%]),其次为不明部位(67[16.2%])和双向发展(57 [13.8%])。上鼓室前最少见(8[1.9%])。上鼓室后胆脂瘤在成人耳最常见(111[40.8%]),中鼓室后耳胆脂瘤在儿童耳最常见(43.0%),P <0.001)。上鼓室前耳胆脂瘤仅见于儿童。

结论:中耳胆脂瘤的出现部位主要有上鼓室前、上鼓室后、中鼓室后、双向发展(包括鼓膜松弛部及鼓膜紧张部参与)和不明部位。上鼓室后和中鼓室后耳胆脂瘤的发病率相似,而上鼓室前耳胆脂瘤和中鼓室后耳胆脂瘤更常见于儿童,上鼓室后胆脂瘤在成人耳最常见。

原始出处:

Leticia Schmidt Rosito,Classification of Cholesteatoma According to Growth Patterns .JAMA Otolaryngol Head Neck Surg,7,Jan,2016

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  2. [GetPortalCommentsPageByObjectIdResponse(id=2058331, encodeId=828f205833168, content=<a href='/topic/show?id=32992240372' target=_blank style='color:#2F92EE;'>#中耳胆脂瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22403, encryptionId=32992240372, topicName=中耳胆脂瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=267e204, createdName=wangyang7958, createdTime=Mon Sep 26 19:14:00 CST 2016, time=2016-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=133825, encodeId=bae9133825fb, content=赞了!深度好文,深入学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Sep 23 20:07:00 CST 2016, time=2016-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823264, encodeId=c8711823264e7, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Thu Jul 07 12:14:00 CST 2016, time=2016-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62866, encodeId=29e862866db, content=值得研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Feb 02 18:03:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62865, encodeId=6e746286530, content=罕见, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Feb 02 18:02:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1456629, encodeId=e4a51456629a8, content=<a href='/topic/show?id=e76d8353054' target=_blank style='color:#2F92EE;'>#胆脂瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83530, encryptionId=e76d8353054, topicName=胆脂瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d75780839, createdName=chenhongpeng, createdTime=Sun Jan 10 03:14:00 CST 2016, time=2016-01-10, status=1, ipAttribution=)]
    2016-09-23 ylzr123

    赞了!深度好文,深入学习。

    0

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    2016-02-02 收获你的美

    值得研究

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2058331, encodeId=828f205833168, content=<a href='/topic/show?id=32992240372' target=_blank style='color:#2F92EE;'>#中耳胆脂瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22403, encryptionId=32992240372, topicName=中耳胆脂瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=267e204, createdName=wangyang7958, createdTime=Mon Sep 26 19:14:00 CST 2016, time=2016-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=133825, encodeId=bae9133825fb, content=赞了!深度好文,深入学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Sep 23 20:07:00 CST 2016, time=2016-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823264, encodeId=c8711823264e7, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Thu Jul 07 12:14:00 CST 2016, time=2016-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62866, encodeId=29e862866db, content=值得研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Feb 02 18:03:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62865, encodeId=6e746286530, content=罕见, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Feb 02 18:02:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1456629, encodeId=e4a51456629a8, content=<a href='/topic/show?id=e76d8353054' target=_blank style='color:#2F92EE;'>#胆脂瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83530, encryptionId=e76d8353054, topicName=胆脂瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d75780839, createdName=chenhongpeng, createdTime=Sun Jan 10 03:14:00 CST 2016, time=2016-01-10, status=1, ipAttribution=)]
    2016-02-02 收获你的美

    罕见

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2058331, encodeId=828f205833168, content=<a href='/topic/show?id=32992240372' target=_blank style='color:#2F92EE;'>#中耳胆脂瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22403, encryptionId=32992240372, topicName=中耳胆脂瘤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=267e204, createdName=wangyang7958, createdTime=Mon Sep 26 19:14:00 CST 2016, time=2016-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=133825, encodeId=bae9133825fb, content=赞了!深度好文,深入学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Sep 23 20:07:00 CST 2016, time=2016-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823264, encodeId=c8711823264e7, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Thu Jul 07 12:14:00 CST 2016, time=2016-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62866, encodeId=29e862866db, content=值得研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Feb 02 18:03:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62865, encodeId=6e746286530, content=罕见, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Feb 02 18:02:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1456629, encodeId=e4a51456629a8, content=<a href='/topic/show?id=e76d8353054' target=_blank style='color:#2F92EE;'>#胆脂瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83530, encryptionId=e76d8353054, topicName=胆脂瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=12d75780839, createdName=chenhongpeng, createdTime=Sun Jan 10 03:14:00 CST 2016, time=2016-01-10, status=1, ipAttribution=)]
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