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Am J Gastroenterol:食管动力障碍疾病的诊断:HRM vs CM

2016-02-16 Mechront 译 MedSci原创

在诊断食管动力障碍方面,使用高分辨率测压(HRM)可能优于常规测压(CM)。研究者进行了一项研究,比较HRM和CM的诊断效应,并通过6个月的多中心随机试验进行验证。研究者将不明原因吞咽障碍患者随机分为两组(CM组或HRM组)。CM组使用Castell和Spechler分类法进行动力障碍性疾病的初步诊断,HRM组则使用Chicago分类法进行初步诊断。确诊则是基于临床结局和随访6个月的疗效。通过两组

在诊断食管动力障碍方面,使用高分辨率测压(HRM)可能优于常规测压(CM)。研究者进行了一项研究,比较HRM和CM的诊断效应,并通过6个月的多中心随机试验进行验证。

研究者将不明原因吞咽障碍患者随机分为两组(CM组或HRM组)。CM组使用Castell和Spechler分类法进行动力障碍性疾病的初步诊断,HRM组则使用Chicago分类法进行初步诊断。确诊则是基于临床结局和随访6个月的疗效。通过两组初步诊断占确诊的百分比进行诊断效应的比较。

最终该研究分析了245名患者的数据,其中CM组有122人,HRM组有123人。HRM组和CM组初步诊断率分别为97% vs84%(P<0.01)。HRM组初步诊断贲门失弛缓症更多(26% vs12%;P<0.01),正常的检查更多见于CM组(52% vs28%; P<0.05)。饭后HRM和CM组的确诊率分别为89%和81%(P=0.07)。此外,CM的耐受性优于HRM(P<0.01)。

研究结果表明,HRM与CM相比,可改善贲门失弛缓症的诊断率;HRM的初步诊断占确诊比例更高,提示HRM可以比CM更早识别食管动力障碍。

原始出处:

Roman S, Huot L,et al.High-Resolution Manometry Improves the Diagnosis of Esophageal Motility Disorders in Patients With Dysphagia: A Randomized Multicenter Study.Am J Gastroenterol. 2016 Feb 2. doi: 10.1038/ajg.2016.1. 


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    2016-06-23 许安
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    2016-02-18 zhouqu_8

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