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Cell Discovery:通过临床试验证实,金银花可抑制新冠病毒复制,加速患者好转

2020-08-09 BioWorld Bio生物世界

通过临床试验证实,金银花汤剂中的miRNA可通过饮用被人体有效吸收,并在体内有效抑制新冠病毒复制,加速新冠患者转阴,表明金银花汤剂治疗可能会极大地帮助治愈新冠患者并阻止COVID-19大流行。

2020年8月5日,南京大学张辰宇教授团队、武汉病毒所张磊砢,及南京市第二医院易永祥等,在Cell Discovery 杂志发表论文,通过临床试验证实,金银花汤剂中的miRNA可通过饮用被人体有效吸收,并在体内有效抑制新冠病毒复制,加速新冠患者转阴,表明金银花汤剂治疗可能会极大地帮助治愈新冠患者并阻止COVID-19大流行。

MicroRNA (miRNA) 是一类内生的、长度约为20-24个核苷酸的小RNA,在细胞内具有多种重要的调节作用。miRNA在不同的物种间高度保守,近年来陆续有研究认为miRNA可以跨物种调控基因表达。

植物miRNA可以调控动物基因表达

2012年,张辰宇教授就在 Cell Research 杂志发表了题为:Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA 的研究论文。

该研究首次发现食物中的外源植物miRNA可以调控哺乳动物靶基因的表达。

张教授团队发现miRNA可在人类和动物的血清和血浆中稳定存在。最近的研究表明来自人血浆的微泡(MV)是微粒、外泌体和其他囊泡结构的混合物,并且人血浆中许多类型的MV含有miRNA。进一步研究表明,miRNAs可以选择性地包裹进MV中,并主动递送到受体细胞中,外源miRNA可以调节靶基因表达和受体细胞功能。

人和动物的血清和血浆中有外源植物miRNA,在血清和血浆中检测到的植物miRNA的一半以上存在于MV中。进一步的体外和体内分析首次证实,食物来源的外源植物MIR168a可以通过小鼠胃肠途径并进入循环和各种器官,特别是在肝脏中跨物种调节小鼠LDLRAP1蛋白表达。

金银花中的miRNA可以抑制甲流病毒

2015年,张辰宇教授团队在 Cell Research 杂志发表了题为:Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses 的研究论文。

该研究发现金银花中的MIR2911可以被小鼠吸收,并直接靶向甲流病毒,从而抑制病毒复制。

MIR2911在金银花汤剂中能够稳定存在,经口服后能被吸收进循环,并递送到各个组织中去。

经检测,给小鼠喂食0.5ml金银花汤后,小鼠肺组织中平均每个细胞含有1600个MIR2911分子,已完全具有生物学功能。进入肺上皮细胞中的MIR2911可以直接与各种流感病毒的mRNA结合,直接抑制病毒的复制。

miR2911可以抑制多种病毒

MIR2911在94%的病毒的基因组上均具有结合位点;后续的细胞水平或动物水平实验也证明了MIR2911在埃博拉病毒、寨卡病毒、非洲猪瘟病毒、中东呼吸热病毒及猪轮状病毒等多种病毒基因组具有结合位点,能够抑制这些病毒的复制。

miR2911可抑制新冠病毒

通过生物信息学分析,研究团队预测SARS-CoV-2基因组中有179个MIR2911结合位点。

然后研究团队通过荧光素酶测定法确认了其中28个结合位点,这些结合位点广泛分布在新冠病毒基因组中,表明MIR2911可能抑制几乎所有SARS-CoV-2蛋白的翻译。

体外细胞实验表明,浓度为13.2 pM的细胞外泌体MIR2911抑制了93%的病毒复制(从4.09×10E9减少到2.87×10E8拷贝/ml),表明吸收的MIR2911直接并充分抑制了SARS-CoV-2的病毒复制。

接下来,研究团队评估了通过饮用金银花汤剂来吸收的MIR2911对SARS-CoV-2复制的抑制作用。

试验结果表明,患者饮用金银花汤剂后,血清外泌体中MIR2911显着上升,且体内病毒水平显着下降。

这些结果表明,可以通过饮用金银花汤剂充分吸收MIR2911,并且吸收的MIR2911显着阻断了SARS-CoV-2的病毒复制。

更重要的是,每天饮用金银花汤剂的患者转阴速度明显快于对照组。

MIR2911能够在金银花汤剂中稳定存在,并通过口服后在人体内直接抑制病毒复制,并加速了患者转阴,金银花汤剂治疗可能会极大地帮助治愈新冠患者并阻止COVID-19大流行。

原始出处:

Li-Kun Zhou, Zhen Zhou, Xia-Ming Jiang,et al.Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients.Cell Discovery volume 6, Article number: 54 (2020).Published: 05 August 2020

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    2023-03-05 lifestar 来自上海

    #金银花#可抑制#新冠病毒#复制,金银花是有名的#抗病毒药物#之一,其它还包括#贯众##藿香##香薷##八角##肉豆蒄##荜拨#等香料,因为从#中医#角度,芳香化湿,而病毒类疾病多与湿,或寒湿有关,因此,#芳香化湿类##中药#正好对症。事实上,象有名的抗流感病毒的药物奥司他韦就来源于#八角#提取。药物研究与开发,也可以顺这个同样的道路。

    0

  2. 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topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40fa18449129, createdName=marongnuan, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=807134, encodeId=452280e13469, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68522530515, createdName=124fe80fm82暂无昵称, createdTime=Sun Aug 09 20:07:20 CST 2020, time=2020-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028417, encodeId=d630102841e9b, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 09 14:16:19 CST 2020, time=2020-08-09, status=1, ipAttribution=)]
    2020-09-23 yahu
  3. [GetPortalCommentsPageByObjectIdResponse(id=2117616, encodeId=8a8d211e6163b, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>可抑制<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>复制,金银花是有名的<a href='/topic/show?id=2b00554848e' target=_blank style='color:#2F92EE;'>#抗病毒药物#</a>之一,其它还包括<a href='/topic/show?id=6dc51053e8ee' target=_blank style='color:#2F92EE;'>#贯众#</a>,<a href='/topic/show?id=34a41053e98a' target=_blank style='color:#2F92EE;'>#藿香#</a>,<a href='/topic/show?id=500e10538009' target=_blank style='color:#2F92EE;'>#香薷#</a>,<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>,<a href='/topic/show?id=07b81053813c' target=_blank style='color:#2F92EE;'>#肉豆蒄#</a>,<a href='/topic/show?id=873b10538297' target=_blank style='color:#2F92EE;'>#荜拨#</a>等香料,因为从<a href='/topic/show?id=c01b2138812' target=_blank style='color:#2F92EE;'>#中医#</a>角度,芳香化湿,而病毒类疾病多与湿,或寒湿有关,因此,<a href='/topic/show?id=2b4c105383c3' target=_blank style='color:#2F92EE;'>#芳香化湿类#</a><a href='/topic/show?id=5c1d22423c8' target=_blank style='color:#2F92EE;'>#中药#</a>正好对症。事实上,象有名的抗流感病毒的药物奥司他韦就来源于<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>提取。药物研究与开发,也可以顺这个同样的道路。, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花), TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=55484, encryptionId=2b00554848e, topicName=抗病毒药物), TopicDto(id=105378, encryptionId=6dc51053e8ee, topicName=贯众), TopicDto(id=105379, encryptionId=34a41053e98a, topicName=藿香), TopicDto(id=105380, encryptionId=500e10538009, topicName=香薷), TopicDto(id=29795, encryptionId=0c2e29e95a5, topicName=八角), TopicDto(id=105381, encryptionId=07b81053813c, topicName=肉豆蒄), TopicDto(id=105382, encryptionId=873b10538297, topicName=荜拨), TopicDto(id=21388, encryptionId=c01b2138812, topicName=中医), TopicDto(id=105383, encryptionId=2b4c105383c3, topicName=芳香化湿类), TopicDto(id=22423, encryptionId=5c1d22423c8, topicName=中药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sun Mar 05 01:53:07 CST 2023, time=2023-03-05, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1783711, encodeId=b0cf1e8371118, content=<a href='/topic/show?id=d195513038' target=_blank style='color:#2F92EE;'>#cover#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5130, encryptionId=d195513038, topicName=cover)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Wed Sep 23 18:16:19 CST 2020, time=2020-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013443, encodeId=53c4201344344, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Feb 03 23:16:19 CST 2021, time=2021-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871899, encodeId=6b8018e1899ba, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 02 02:16:19 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962198, encodeId=cc6d1962198c8, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Feb 01 12:16:19 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512365, encodeId=2d15151236569, content=<a href='/topic/show?id=6a15e09150c' target=_blank style='color:#2F92EE;'>#病毒复制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40fa18449129, createdName=marongnuan, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=807134, encodeId=452280e13469, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68522530515, createdName=124fe80fm82暂无昵称, createdTime=Sun Aug 09 20:07:20 CST 2020, time=2020-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028417, encodeId=d630102841e9b, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 09 14:16:19 CST 2020, time=2020-08-09, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2117616, encodeId=8a8d211e6163b, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>可抑制<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>复制,金银花是有名的<a href='/topic/show?id=2b00554848e' target=_blank style='color:#2F92EE;'>#抗病毒药物#</a>之一,其它还包括<a href='/topic/show?id=6dc51053e8ee' target=_blank style='color:#2F92EE;'>#贯众#</a>,<a href='/topic/show?id=34a41053e98a' target=_blank style='color:#2F92EE;'>#藿香#</a>,<a href='/topic/show?id=500e10538009' target=_blank style='color:#2F92EE;'>#香薷#</a>,<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>,<a href='/topic/show?id=07b81053813c' target=_blank style='color:#2F92EE;'>#肉豆蒄#</a>,<a href='/topic/show?id=873b10538297' target=_blank style='color:#2F92EE;'>#荜拨#</a>等香料,因为从<a href='/topic/show?id=c01b2138812' target=_blank style='color:#2F92EE;'>#中医#</a>角度,芳香化湿,而病毒类疾病多与湿,或寒湿有关,因此,<a href='/topic/show?id=2b4c105383c3' target=_blank style='color:#2F92EE;'>#芳香化湿类#</a><a href='/topic/show?id=5c1d22423c8' target=_blank style='color:#2F92EE;'>#中药#</a>正好对症。事实上,象有名的抗流感病毒的药物奥司他韦就来源于<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>提取。药物研究与开发,也可以顺这个同样的道路。, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花), TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=55484, encryptionId=2b00554848e, topicName=抗病毒药物), TopicDto(id=105378, encryptionId=6dc51053e8ee, topicName=贯众), TopicDto(id=105379, encryptionId=34a41053e98a, topicName=藿香), TopicDto(id=105380, encryptionId=500e10538009, topicName=香薷), TopicDto(id=29795, encryptionId=0c2e29e95a5, topicName=八角), TopicDto(id=105381, encryptionId=07b81053813c, topicName=肉豆蒄), TopicDto(id=105382, encryptionId=873b10538297, topicName=荜拨), TopicDto(id=21388, encryptionId=c01b2138812, topicName=中医), TopicDto(id=105383, encryptionId=2b4c105383c3, topicName=芳香化湿类), TopicDto(id=22423, encryptionId=5c1d22423c8, topicName=中药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sun Mar 05 01:53:07 CST 2023, time=2023-03-05, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1783711, encodeId=b0cf1e8371118, content=<a href='/topic/show?id=d195513038' target=_blank style='color:#2F92EE;'>#cover#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5130, encryptionId=d195513038, topicName=cover)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Wed Sep 23 18:16:19 CST 2020, time=2020-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013443, encodeId=53c4201344344, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Feb 03 23:16:19 CST 2021, time=2021-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871899, encodeId=6b8018e1899ba, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 02 02:16:19 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962198, encodeId=cc6d1962198c8, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Feb 01 12:16:19 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512365, encodeId=2d15151236569, content=<a href='/topic/show?id=6a15e09150c' target=_blank style='color:#2F92EE;'>#病毒复制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40fa18449129, createdName=marongnuan, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=807134, encodeId=452280e13469, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68522530515, createdName=124fe80fm82暂无昵称, createdTime=Sun Aug 09 20:07:20 CST 2020, time=2020-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028417, encodeId=d630102841e9b, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 09 14:16:19 CST 2020, time=2020-08-09, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2117616, encodeId=8a8d211e6163b, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>可抑制<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>复制,金银花是有名的<a href='/topic/show?id=2b00554848e' target=_blank style='color:#2F92EE;'>#抗病毒药物#</a>之一,其它还包括<a href='/topic/show?id=6dc51053e8ee' target=_blank style='color:#2F92EE;'>#贯众#</a>,<a href='/topic/show?id=34a41053e98a' target=_blank style='color:#2F92EE;'>#藿香#</a>,<a href='/topic/show?id=500e10538009' target=_blank style='color:#2F92EE;'>#香薷#</a>,<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>,<a href='/topic/show?id=07b81053813c' target=_blank style='color:#2F92EE;'>#肉豆蒄#</a>,<a href='/topic/show?id=873b10538297' target=_blank style='color:#2F92EE;'>#荜拨#</a>等香料,因为从<a href='/topic/show?id=c01b2138812' target=_blank style='color:#2F92EE;'>#中医#</a>角度,芳香化湿,而病毒类疾病多与湿,或寒湿有关,因此,<a href='/topic/show?id=2b4c105383c3' target=_blank style='color:#2F92EE;'>#芳香化湿类#</a><a href='/topic/show?id=5c1d22423c8' target=_blank style='color:#2F92EE;'>#中药#</a>正好对症。事实上,象有名的抗流感病毒的药物奥司他韦就来源于<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>提取。药物研究与开发,也可以顺这个同样的道路。, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花), TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=55484, encryptionId=2b00554848e, topicName=抗病毒药物), TopicDto(id=105378, encryptionId=6dc51053e8ee, topicName=贯众), TopicDto(id=105379, encryptionId=34a41053e98a, topicName=藿香), TopicDto(id=105380, encryptionId=500e10538009, topicName=香薷), TopicDto(id=29795, encryptionId=0c2e29e95a5, topicName=八角), TopicDto(id=105381, encryptionId=07b81053813c, topicName=肉豆蒄), TopicDto(id=105382, encryptionId=873b10538297, topicName=荜拨), TopicDto(id=21388, encryptionId=c01b2138812, topicName=中医), TopicDto(id=105383, encryptionId=2b4c105383c3, topicName=芳香化湿类), TopicDto(id=22423, encryptionId=5c1d22423c8, topicName=中药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sun Mar 05 01:53:07 CST 2023, time=2023-03-05, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1783711, encodeId=b0cf1e8371118, content=<a href='/topic/show?id=d195513038' target=_blank style='color:#2F92EE;'>#cover#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5130, encryptionId=d195513038, topicName=cover)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Wed Sep 23 18:16:19 CST 2020, time=2020-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013443, encodeId=53c4201344344, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Feb 03 23:16:19 CST 2021, time=2021-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871899, encodeId=6b8018e1899ba, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 02 02:16:19 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962198, encodeId=cc6d1962198c8, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Feb 01 12:16:19 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512365, encodeId=2d15151236569, content=<a href='/topic/show?id=6a15e09150c' target=_blank style='color:#2F92EE;'>#病毒复制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40fa18449129, createdName=marongnuan, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=807134, encodeId=452280e13469, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68522530515, createdName=124fe80fm82暂无昵称, createdTime=Sun Aug 09 20:07:20 CST 2020, time=2020-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028417, encodeId=d630102841e9b, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 09 14:16:19 CST 2020, time=2020-08-09, status=1, ipAttribution=)]
    2021-02-01 维他命
  6. [GetPortalCommentsPageByObjectIdResponse(id=2117616, encodeId=8a8d211e6163b, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>可抑制<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>复制,金银花是有名的<a href='/topic/show?id=2b00554848e' target=_blank style='color:#2F92EE;'>#抗病毒药物#</a>之一,其它还包括<a href='/topic/show?id=6dc51053e8ee' target=_blank style='color:#2F92EE;'>#贯众#</a>,<a href='/topic/show?id=34a41053e98a' target=_blank style='color:#2F92EE;'>#藿香#</a>,<a href='/topic/show?id=500e10538009' target=_blank style='color:#2F92EE;'>#香薷#</a>,<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>,<a href='/topic/show?id=07b81053813c' target=_blank style='color:#2F92EE;'>#肉豆蒄#</a>,<a href='/topic/show?id=873b10538297' target=_blank style='color:#2F92EE;'>#荜拨#</a>等香料,因为从<a href='/topic/show?id=c01b2138812' target=_blank style='color:#2F92EE;'>#中医#</a>角度,芳香化湿,而病毒类疾病多与湿,或寒湿有关,因此,<a href='/topic/show?id=2b4c105383c3' target=_blank style='color:#2F92EE;'>#芳香化湿类#</a><a href='/topic/show?id=5c1d22423c8' target=_blank style='color:#2F92EE;'>#中药#</a>正好对症。事实上,象有名的抗流感病毒的药物奥司他韦就来源于<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>提取。药物研究与开发,也可以顺这个同样的道路。, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花), TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=55484, encryptionId=2b00554848e, topicName=抗病毒药物), TopicDto(id=105378, encryptionId=6dc51053e8ee, topicName=贯众), TopicDto(id=105379, encryptionId=34a41053e98a, topicName=藿香), TopicDto(id=105380, encryptionId=500e10538009, topicName=香薷), TopicDto(id=29795, encryptionId=0c2e29e95a5, topicName=八角), TopicDto(id=105381, encryptionId=07b81053813c, topicName=肉豆蒄), TopicDto(id=105382, encryptionId=873b10538297, topicName=荜拨), TopicDto(id=21388, encryptionId=c01b2138812, topicName=中医), TopicDto(id=105383, encryptionId=2b4c105383c3, topicName=芳香化湿类), TopicDto(id=22423, encryptionId=5c1d22423c8, topicName=中药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sun Mar 05 01:53:07 CST 2023, time=2023-03-05, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1783711, encodeId=b0cf1e8371118, content=<a href='/topic/show?id=d195513038' target=_blank style='color:#2F92EE;'>#cover#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5130, encryptionId=d195513038, topicName=cover)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Wed Sep 23 18:16:19 CST 2020, time=2020-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013443, encodeId=53c4201344344, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Feb 03 23:16:19 CST 2021, time=2021-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871899, encodeId=6b8018e1899ba, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 02 02:16:19 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962198, encodeId=cc6d1962198c8, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Feb 01 12:16:19 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512365, encodeId=2d15151236569, content=<a href='/topic/show?id=6a15e09150c' target=_blank style='color:#2F92EE;'>#病毒复制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40fa18449129, createdName=marongnuan, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=807134, encodeId=452280e13469, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68522530515, createdName=124fe80fm82暂无昵称, createdTime=Sun Aug 09 20:07:20 CST 2020, time=2020-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028417, encodeId=d630102841e9b, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 09 14:16:19 CST 2020, time=2020-08-09, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=2117616, encodeId=8a8d211e6163b, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>可抑制<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>复制,金银花是有名的<a href='/topic/show?id=2b00554848e' target=_blank style='color:#2F92EE;'>#抗病毒药物#</a>之一,其它还包括<a href='/topic/show?id=6dc51053e8ee' target=_blank style='color:#2F92EE;'>#贯众#</a>,<a href='/topic/show?id=34a41053e98a' target=_blank style='color:#2F92EE;'>#藿香#</a>,<a href='/topic/show?id=500e10538009' target=_blank style='color:#2F92EE;'>#香薷#</a>,<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>,<a href='/topic/show?id=07b81053813c' target=_blank style='color:#2F92EE;'>#肉豆蒄#</a>,<a href='/topic/show?id=873b10538297' target=_blank style='color:#2F92EE;'>#荜拨#</a>等香料,因为从<a href='/topic/show?id=c01b2138812' target=_blank style='color:#2F92EE;'>#中医#</a>角度,芳香化湿,而病毒类疾病多与湿,或寒湿有关,因此,<a href='/topic/show?id=2b4c105383c3' target=_blank style='color:#2F92EE;'>#芳香化湿类#</a><a href='/topic/show?id=5c1d22423c8' target=_blank style='color:#2F92EE;'>#中药#</a>正好对症。事实上,象有名的抗流感病毒的药物奥司他韦就来源于<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>提取。药物研究与开发,也可以顺这个同样的道路。, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花), TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=55484, encryptionId=2b00554848e, topicName=抗病毒药物), TopicDto(id=105378, encryptionId=6dc51053e8ee, topicName=贯众), TopicDto(id=105379, encryptionId=34a41053e98a, topicName=藿香), TopicDto(id=105380, encryptionId=500e10538009, topicName=香薷), TopicDto(id=29795, encryptionId=0c2e29e95a5, topicName=八角), TopicDto(id=105381, encryptionId=07b81053813c, topicName=肉豆蒄), TopicDto(id=105382, encryptionId=873b10538297, topicName=荜拨), TopicDto(id=21388, encryptionId=c01b2138812, topicName=中医), TopicDto(id=105383, encryptionId=2b4c105383c3, topicName=芳香化湿类), TopicDto(id=22423, encryptionId=5c1d22423c8, topicName=中药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sun Mar 05 01:53:07 CST 2023, time=2023-03-05, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1783711, encodeId=b0cf1e8371118, content=<a href='/topic/show?id=d195513038' target=_blank style='color:#2F92EE;'>#cover#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5130, encryptionId=d195513038, topicName=cover)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Wed Sep 23 18:16:19 CST 2020, time=2020-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013443, encodeId=53c4201344344, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Feb 03 23:16:19 CST 2021, time=2021-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871899, encodeId=6b8018e1899ba, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 02 02:16:19 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962198, encodeId=cc6d1962198c8, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Feb 01 12:16:19 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512365, encodeId=2d15151236569, content=<a href='/topic/show?id=6a15e09150c' target=_blank style='color:#2F92EE;'>#病毒复制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40fa18449129, createdName=marongnuan, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=807134, encodeId=452280e13469, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68522530515, createdName=124fe80fm82暂无昵称, createdTime=Sun Aug 09 20:07:20 CST 2020, time=2020-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028417, encodeId=d630102841e9b, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 09 14:16:19 CST 2020, time=2020-08-09, status=1, ipAttribution=)]
    2020-08-11 yankaienglish
  8. [GetPortalCommentsPageByObjectIdResponse(id=2117616, encodeId=8a8d211e6163b, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>可抑制<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>复制,金银花是有名的<a href='/topic/show?id=2b00554848e' target=_blank style='color:#2F92EE;'>#抗病毒药物#</a>之一,其它还包括<a href='/topic/show?id=6dc51053e8ee' target=_blank style='color:#2F92EE;'>#贯众#</a>,<a href='/topic/show?id=34a41053e98a' target=_blank style='color:#2F92EE;'>#藿香#</a>,<a href='/topic/show?id=500e10538009' target=_blank style='color:#2F92EE;'>#香薷#</a>,<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>,<a href='/topic/show?id=07b81053813c' target=_blank style='color:#2F92EE;'>#肉豆蒄#</a>,<a href='/topic/show?id=873b10538297' target=_blank style='color:#2F92EE;'>#荜拨#</a>等香料,因为从<a href='/topic/show?id=c01b2138812' target=_blank style='color:#2F92EE;'>#中医#</a>角度,芳香化湿,而病毒类疾病多与湿,或寒湿有关,因此,<a href='/topic/show?id=2b4c105383c3' target=_blank style='color:#2F92EE;'>#芳香化湿类#</a><a href='/topic/show?id=5c1d22423c8' target=_blank style='color:#2F92EE;'>#中药#</a>正好对症。事实上,象有名的抗流感病毒的药物奥司他韦就来源于<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>提取。药物研究与开发,也可以顺这个同样的道路。, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花), TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=55484, encryptionId=2b00554848e, topicName=抗病毒药物), TopicDto(id=105378, encryptionId=6dc51053e8ee, topicName=贯众), TopicDto(id=105379, encryptionId=34a41053e98a, topicName=藿香), TopicDto(id=105380, encryptionId=500e10538009, topicName=香薷), TopicDto(id=29795, encryptionId=0c2e29e95a5, topicName=八角), TopicDto(id=105381, encryptionId=07b81053813c, topicName=肉豆蒄), TopicDto(id=105382, encryptionId=873b10538297, topicName=荜拨), TopicDto(id=21388, encryptionId=c01b2138812, topicName=中医), TopicDto(id=105383, encryptionId=2b4c105383c3, topicName=芳香化湿类), TopicDto(id=22423, encryptionId=5c1d22423c8, topicName=中药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sun Mar 05 01:53:07 CST 2023, time=2023-03-05, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1783711, encodeId=b0cf1e8371118, content=<a href='/topic/show?id=d195513038' target=_blank style='color:#2F92EE;'>#cover#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5130, encryptionId=d195513038, topicName=cover)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Wed Sep 23 18:16:19 CST 2020, time=2020-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013443, encodeId=53c4201344344, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Feb 03 23:16:19 CST 2021, time=2021-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871899, encodeId=6b8018e1899ba, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 02 02:16:19 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962198, encodeId=cc6d1962198c8, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Feb 01 12:16:19 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512365, encodeId=2d15151236569, content=<a href='/topic/show?id=6a15e09150c' target=_blank style='color:#2F92EE;'>#病毒复制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40fa18449129, createdName=marongnuan, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=807134, encodeId=452280e13469, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68522530515, createdName=124fe80fm82暂无昵称, createdTime=Sun Aug 09 20:07:20 CST 2020, time=2020-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028417, encodeId=d630102841e9b, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 09 14:16:19 CST 2020, time=2020-08-09, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=2117616, encodeId=8a8d211e6163b, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>可抑制<a href='/topic/show?id=65b05806579' target=_blank style='color:#2F92EE;'>#新冠病毒#</a>复制,金银花是有名的<a href='/topic/show?id=2b00554848e' target=_blank style='color:#2F92EE;'>#抗病毒药物#</a>之一,其它还包括<a href='/topic/show?id=6dc51053e8ee' target=_blank style='color:#2F92EE;'>#贯众#</a>,<a href='/topic/show?id=34a41053e98a' target=_blank style='color:#2F92EE;'>#藿香#</a>,<a href='/topic/show?id=500e10538009' target=_blank style='color:#2F92EE;'>#香薷#</a>,<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>,<a href='/topic/show?id=07b81053813c' target=_blank style='color:#2F92EE;'>#肉豆蒄#</a>,<a href='/topic/show?id=873b10538297' target=_blank style='color:#2F92EE;'>#荜拨#</a>等香料,因为从<a href='/topic/show?id=c01b2138812' target=_blank style='color:#2F92EE;'>#中医#</a>角度,芳香化湿,而病毒类疾病多与湿,或寒湿有关,因此,<a href='/topic/show?id=2b4c105383c3' target=_blank style='color:#2F92EE;'>#芳香化湿类#</a><a href='/topic/show?id=5c1d22423c8' target=_blank style='color:#2F92EE;'>#中药#</a>正好对症。事实上,象有名的抗流感病毒的药物奥司他韦就来源于<a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=0c2e29e95a5' target=_blank style='color:#2F92EE;'>#八角#</a></a>提取。药物研究与开发,也可以顺这个同样的道路。, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花), TopicDto(id=58065, encryptionId=65b05806579, topicName=新冠病毒), TopicDto(id=55484, encryptionId=2b00554848e, topicName=抗病毒药物), TopicDto(id=105378, encryptionId=6dc51053e8ee, topicName=贯众), TopicDto(id=105379, encryptionId=34a41053e98a, topicName=藿香), TopicDto(id=105380, encryptionId=500e10538009, topicName=香薷), TopicDto(id=29795, encryptionId=0c2e29e95a5, topicName=八角), TopicDto(id=105381, encryptionId=07b81053813c, topicName=肉豆蒄), TopicDto(id=105382, encryptionId=873b10538297, topicName=荜拨), TopicDto(id=21388, encryptionId=c01b2138812, topicName=中医), TopicDto(id=105383, encryptionId=2b4c105383c3, topicName=芳香化湿类), TopicDto(id=22423, encryptionId=5c1d22423c8, topicName=中药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sun Mar 05 01:53:07 CST 2023, time=2023-03-05, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1783711, encodeId=b0cf1e8371118, content=<a href='/topic/show?id=d195513038' target=_blank style='color:#2F92EE;'>#cover#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5130, encryptionId=d195513038, topicName=cover)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Wed Sep 23 18:16:19 CST 2020, time=2020-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013443, encodeId=53c4201344344, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Feb 03 23:16:19 CST 2021, time=2021-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1871899, encodeId=6b8018e1899ba, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 02 02:16:19 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962198, encodeId=cc6d1962198c8, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Feb 01 12:16:19 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512365, encodeId=2d15151236569, content=<a href='/topic/show?id=6a15e09150c' target=_blank style='color:#2F92EE;'>#病毒复制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank style='color:#2F92EE;'>#金银花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96235, encryptionId=7bab96235f5, topicName=金银花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=40fa18449129, createdName=marongnuan, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=807134, encodeId=452280e13469, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68522530515, createdName=124fe80fm82暂无昵称, createdTime=Sun Aug 09 20:07:20 CST 2020, time=2020-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028417, encodeId=d630102841e9b, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Aug 09 14:16:19 CST 2020, time=2020-08-09, status=1, ipAttribution=)]
    2020-08-09 124fe80fm82暂无昵称

    学习了

    0

  10. 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authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Dec 02 02:16:19 CST 2020, time=2020-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1962198, encodeId=cc6d1962198c8, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3ff68, createdName=维他命, createdTime=Mon Feb 01 12:16:19 CST 2021, time=2021-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512365, encodeId=2d15151236569, content=<a href='/topic/show?id=6a15e09150c' target=_blank style='color:#2F92EE;'>#病毒复制#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70915, encryptionId=6a15e09150c, topicName=病毒复制)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a2310462124, createdName=12498623m96暂无昵称, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1587900, encodeId=bcb9158e9005d, content=<a href='/topic/show?id=cb1e1006ebd' target=_blank style='color:#2F92EE;'>#ISC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10067, encryptionId=cb1e1006ebd, topicName=ISC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=173417575755, createdName=yankaienglish, createdTime=Tue Aug 11 02:16:19 CST 2020, time=2020-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597001, encodeId=9cc0159e00158, content=<a href='/topic/show?id=7bab96235f5' target=_blank 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    2020-08-09 公卫新人

    新冠肺炎,疫情何时才能消失

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