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Advanced Materials:奇迹!有机印刷油墨将帮助盲人恢复视力!

2018-05-07 小通 生物通

以色列特拉维夫大学和瑞典林雪平大学(Link?ping University)合作开发了一款简单的视网膜假体。构成这种假体的原材料非常廉价,是广泛使用在化妆品和印刷油墨中的有机颜料。将它们排列成微小的像素,好比纳米级数码相机传感器,研究人员希望未来它能惠及普罗大众。


以色列特拉维夫大学和瑞典林雪平大学(Link?ping University)合作开发了一款简单的视网膜假体。构成这种假体的原材料非常廉价,是广泛使用在化妆品和印刷油墨中的有机颜料。将它们排列成微小的像素,好比纳米级数码相机传感器,研究人员希望未来它能惠及普罗大众。

(瑞典)林雪平大学有机电子学实验室有机纳米晶体小组高级调查员Eric Glowacki领导的研究团队开发了一种小而简便的光活性膜,它能将光脉冲转化成电信号,电信号进而刺激神经元在脑内生成视觉图像,这种人工视网膜可能会使盲人恢复视力。在瑞典团队开发纳米材料和电子设备的基础上,以色列、意大利和奥地利的研究人员合作对其进行技术优化,视力恢复实验由特拉维夫大学Yael Hanein团队领导,他们是研究电子-神经系统接口的世界领导者。

文章发表在著名学术杂志《Advanced Materials》。

视网膜由几层薄薄的细胞层组成。眼球后部的光敏神经元可以将射入光转换为电信号,其他细胞负责处理神经冲动并将它们传导至大脑相应区域,视觉皮层(visual cortex)。如果人因为感光细胞退化,所以无法将光转化成电脉冲而失去视力,就可以植入这种人工视网膜。

人工视网膜是一张富含光敏材料的薄圆形膜,类似数码照相机传感器的单个像素,每个像素都是一颗微型半导体纳米晶体颜料(比细胞薄100倍、直径小于人类头发)。这种颜料价格低廉而且无毒,常用于商业化妆品和纹身油墨。

“我们已经优化了光活性膜的近红外光,因为骨骼、血液和皮肤等生物组织在近红外光下最透明,”Eric Glowacki说。“这增加了这种薄膜的其他用途。”

Eric Glowacki正在以红光脉冲检测神经元刺激设备的电反应

他把人工视网膜描述为一个中间含晶体、外围是小金属环的微型甜甜圈。它无需任何外接连接器,神经细胞的激活也没有延迟性。

“如果我们要控制神经细胞激活,反应时间必须很短,”特拉维夫大学博后研究员David Rand说。“我们已经证明,我们的装置可直接激活神经元,不仅可以刺激大脑神经元,而且还可以刺激其他非功能性视网膜神经元。” 

原始出处:

David Rand ,et al.Direct Electrical Neurostimulation with Organic Pigment Photocapacitors. Advanced Materials.https://doi.org/10.1002/adma.201707292

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    2018-08-11 ymljack
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    2018-05-16 半夏微凉

    学习了谢谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1743601, encodeId=24ab1e43601d6, content=<a href='/topic/show?id=c92c42e3055' target=_blank style='color:#2F92EE;'>#复视#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42730, encryptionId=c92c42e3055, topicName=复视)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2c8d35156774, createdName=ymljack, createdTime=Sat Aug 11 03:31:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020051, encodeId=c3bf20200517b, content=<a href='/topic/show?id=8544202eff' target=_blank style='color:#2F92EE;'>#Advanced#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2027, encryptionId=8544202eff, topicName=Advanced)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5cb32500112, createdName=1508842480_96220437, createdTime=Sat Jul 14 23:31:00 CST 2018, time=2018-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1717460, encodeId=cf791e17460eb, content=<a href='/topic/show?id=29ffe24064c' target=_blank style='color:#2F92EE;'>#盲人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72406, encryptionId=29ffe24064c, topicName=盲人)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bf2532414379, createdName=anminleiryan, createdTime=Fri Nov 16 21:31:00 CST 2018, time=2018-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315605, encodeId=c5503156054b, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Wed May 16 08:25:37 CST 2018, time=2018-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312869, encodeId=f2a63128699d, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Mon May 07 13:38:44 CST 2018, time=2018-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312862, encodeId=99393128625a, content=好文.值得点赞!认真学习.应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=169, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Mon May 07 12:28:19 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-07 131****1460

    学习了受益匪浅

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1743601, encodeId=24ab1e43601d6, content=<a href='/topic/show?id=c92c42e3055' target=_blank style='color:#2F92EE;'>#复视#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42730, encryptionId=c92c42e3055, topicName=复视)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2c8d35156774, createdName=ymljack, createdTime=Sat Aug 11 03:31:00 CST 2018, time=2018-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020051, encodeId=c3bf20200517b, content=<a href='/topic/show?id=8544202eff' target=_blank style='color:#2F92EE;'>#Advanced#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2027, encryptionId=8544202eff, topicName=Advanced)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5cb32500112, createdName=1508842480_96220437, createdTime=Sat Jul 14 23:31:00 CST 2018, time=2018-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1717460, encodeId=cf791e17460eb, content=<a href='/topic/show?id=29ffe24064c' target=_blank style='color:#2F92EE;'>#盲人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72406, encryptionId=29ffe24064c, topicName=盲人)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bf2532414379, createdName=anminleiryan, createdTime=Fri Nov 16 21:31:00 CST 2018, time=2018-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315605, encodeId=c5503156054b, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Wed May 16 08:25:37 CST 2018, time=2018-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312869, encodeId=f2a63128699d, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Mon May 07 13:38:44 CST 2018, time=2018-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312862, encodeId=99393128625a, content=好文.值得点赞!认真学习.应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=169, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Mon May 07 12:28:19 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-07 lietome2

    好文.值得点赞!认真学习.应用于实践!谢谢分享给广大同好!

    0

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