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Blood Transfus:意大利甲型肝炎病毒爆发的男男性行为者中戊型肝炎病毒感染率

2020-10-04 MedSci原创 MedSci原创

戊型肝炎病毒(HEV)的传播途径仍未完全明确。本研究中,我们评估了HEV性传播的可能性,研究结果已在线发表于Blood Transfus。

戊型肝炎病毒(HEV)的传播途径仍未完全明确。本研究中,我们评估了HEV性传播的可能性,研究结果已在线发表于Blood Transfus。

纳入多国甲型肝炎病毒(HAV)爆发的196名意大利男男性行为者(MSM)和与MSM相同的地区和省份选取的3,912名意大利男性献血者的样本,评估并比较HEV的感染率,评估戊型肝炎病毒性传播风险。选择研究参与者的原因是,意大利献血者中的HEV流行率在不同地理区域之间存在巨大差异。

 

结果显示,献血者和MSM的抗HEV IgG流行率分别为14.8%和5.6%。校正后的抗HEV IgG流行率在MSM中显著低于献血者(OR,0.40;95%置信区间[CI]:0.22-0.75;P<0.01),在意大利北方(OR,0.45;95%CI:0.37-0.55;P<0.01)和南方(OR,0. 45;95% CI:0.35-0.58;p<0.01)意大利的居民比中部的居民要高,而50岁以上的参与者的流行率明显高于50岁以下的参与者(OR,1.83;95% CI:1.48-2.27;p<0.01)。

总之,该研究结果表明,性行为在HEV传播中不具有相关作用。特别是,HEV的性传播不太可能影响人群层面的HEV感染率。

 

原始出处:

 

Enea SpadaAngela Costantino, et al., Hepatitis E virus infection prevalence among men who have sex with men involved in a hepatitis A virus outbreak in Italy. Blood Transfus. 2019 Nov;17(6):428-432. doi: 10.2450/2019.0209-19.

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    2021-01-23 bsmagic9140
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    2020-10-06 xugc
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