Baidu
map

Eur Arch Otorhinolaryngol:耳硬化不同阶段的3D液体衰减反转恢复磁共振成像研究

2018-09-20 AlexYang MedSci原创

最近,有研究人员通过3D-FLAIR序列核磁共振成像(MRI)和钆给药或者不给药(-/+Gd)对耳硬化患者进行了研究,从而理解是否3D FLAIR MRI序列的放射学发现与耳硬化患者一些临床特性相关,比如感官神经参与、疾病持续时间、患者性别和其他因素。研究包括了38名受不同阶段单边或者双边耳硬化的患者,并且他们均经历了3D FLAIR MRI+/- Gd。11名听力正常,但因为其他小的疾病而参与了

最近,有研究人员通过3D-FLAIR序列核磁共振成像(MRI)和钆给药或者不给药(-/+Gd)对耳硬化患者进行了研究,从而理解是否3D FLAIR MRI序列的放射学发现与耳硬化患者一些临床特性相关,比如感官神经参与、疾病持续时间、患者性别和其他因素。

研究包括了38名受不同阶段单边或者双边耳硬化的患者,并且他们均经历了3D FLAIR MRI+/- Gd。11名听力正常,但因为其他小的疾病而参与了3T MRI,且与耳硬化无关。这些参与者作为研究的对照。研究发现,3D FLAIR MRI与耳硬化的一些临床特性显著相关,比如耳蜗损伤的严重度和疾病持续的时间。他们的发现表明了3D FLAIR MRI的不同模式可能依赖耳蜗中血迷路屏障的损伤情况,并且与耳硬化患者中不同阶段的耳蜗参与相关。

最后,研究人员指出,他们的发现能够为耳硬化患者中耳蜗损伤的致病机制提供理解,并且也许具有更深的预后价值。他们的结果使得使用 3D-FLAIR序列在任何耳硬化药物治疗中效果的评估中成为可能,并且还可以选择那些患者适合治疗。

原始出处:

Berrettini S, Lombardo F, Bruschini L et al. 3D fluid attenuated inversion recovery (FLAIR) magnetic resonance imaging at different stages of otosclerosis. Eur Arch Otorhinolaryngol. 06 Sep 2018.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1701460, encodeId=15d61e0146038, content=<a href='/topic/show?id=89fc8049e53' target=_blank style='color:#2F92EE;'>#耳硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80497, encryptionId=89fc8049e53, topicName=耳硬化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=515d30375051, createdName=jambiya, createdTime=Tue Oct 09 03:23:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336067, encodeId=e929133606e3b, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Sep 22 13:23:00 CST 2018, time=2018-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341630, encodeId=1d231341630dd, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Sat Sep 22 13:23:00 CST 2018, time=2018-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=345899, encodeId=16c4345899c0, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Sep 20 22:56:40 CST 2018, time=2018-09-20, status=1, ipAttribution=)]
    2018-10-09 jambiya
  2. [GetPortalCommentsPageByObjectIdResponse(id=1701460, encodeId=15d61e0146038, content=<a href='/topic/show?id=89fc8049e53' target=_blank style='color:#2F92EE;'>#耳硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80497, encryptionId=89fc8049e53, topicName=耳硬化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=515d30375051, createdName=jambiya, createdTime=Tue Oct 09 03:23:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336067, encodeId=e929133606e3b, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Sep 22 13:23:00 CST 2018, time=2018-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341630, encodeId=1d231341630dd, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Sat Sep 22 13:23:00 CST 2018, time=2018-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=345899, encodeId=16c4345899c0, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Sep 20 22:56:40 CST 2018, time=2018-09-20, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1701460, encodeId=15d61e0146038, content=<a href='/topic/show?id=89fc8049e53' target=_blank style='color:#2F92EE;'>#耳硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80497, encryptionId=89fc8049e53, topicName=耳硬化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=515d30375051, createdName=jambiya, createdTime=Tue Oct 09 03:23:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336067, encodeId=e929133606e3b, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Sep 22 13:23:00 CST 2018, time=2018-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341630, encodeId=1d231341630dd, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Sat Sep 22 13:23:00 CST 2018, time=2018-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=345899, encodeId=16c4345899c0, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Sep 20 22:56:40 CST 2018, time=2018-09-20, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1701460, encodeId=15d61e0146038, content=<a href='/topic/show?id=89fc8049e53' target=_blank style='color:#2F92EE;'>#耳硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80497, encryptionId=89fc8049e53, topicName=耳硬化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=515d30375051, createdName=jambiya, createdTime=Tue Oct 09 03:23:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336067, encodeId=e929133606e3b, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Sep 22 13:23:00 CST 2018, time=2018-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341630, encodeId=1d231341630dd, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Sat Sep 22 13:23:00 CST 2018, time=2018-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=345899, encodeId=16c4345899c0, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Sep 20 22:56:40 CST 2018, time=2018-09-20, status=1, ipAttribution=)]
    2018-09-20 天地飞扬

    了解一下,谢谢分享!

    0

相关资讯

J Laryngol Otol:晚期耳硬化症镫骨外科手术的听力结果

患有晚期耳硬化症的病人往往表现出符合耳蜗移植的听力阈值。最近,有研究人员进行了旨在探究是否镫骨外科手术在他们的研究病人组中可以提供临床显著性听力改善效果的研究。研究人员评估了术前和术后患有晚期耳硬化病人的听力结果以及确定了这些病人中那些需要进一步的外科手术,包括了耳蜗移植。2002年到2015年之间,在研究人员所在机构中,总共有252名病人经历了初次的镫骨外科手术。25名病人中的28只耳朵确认为晚

Am J Otolaryng:耳软骨囊耳硬化病人的耳蜗植入

最近,有研究人员评估了耳软骨囊耳硬化病人的耳蜗植入后的效果。研究人员对6名病人(7只耳朵)进行了回顾性研究。在研究的6名病人中(7只耳朵),5名病人具有严重到重度感觉神经性听力损失;1名病人具有适度到重度感官神经听力损失,并且具有耳硬化的放射证据。所有参与的病人都为男性,有或者没有镫骨手术历史。研究人员对7只耳朵进行了耳蜗植入实验。5名具有严重到重度感官神经听力损失的病人接受了核轮廓提前围耳蜗电极

Baidu
map
Baidu
map
Baidu
map