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Am J Clin Nutr:侯凡凡等发现每日0.8 mg叶酸可降低伴糖尿病高血压患者34%卒中风险

2017-02-06 卢芳 中国循环杂志

高血糖是卒中的重要危险因素。近期南方医科大学侯凡凡等在高血压人群中进行的研究显示,空腹血糖≥7 mmol/L或糖尿病均可增加首次卒中风险,而补充叶酸可降低34%的这种风险。 研究显示,空腹血糖<5 mmol/L者首次卒中发生率为2.6%,而空腹血糖≥7 mmol/L或糖尿病者则高达6%。 而每日补充0.8 mg叶酸,对于空腹血糖≥5 mmol/L者都有预防卒中作用,但在空腹血糖

高血糖是卒中的重要危险因素。近期南方医科大学侯凡凡等在高血压人群中进行的研究显示,空腹血糖≥7 mmol/L糖尿病均可增加首次卒中风险,而补充叶酸可降低34%的这种风险。 

研究显示,空腹血糖<5 mmol/L者首次卒中发生率为2.6%,而空腹血糖≥7 mmol/L糖尿病者则高达6% 

而每日补充0.8 mg叶酸,对于空腹血糖≥5 mmol/L者都有预防卒中作用,但在空腹血糖≥7 mmol/L糖尿病者中作用更为显著。 

这项随机双盲研究共纳入20327例无卒中或心梗病史的高血压患者,其中10167例服用依那普利10 mg/d10160例在此基础上再每日补充0.8 mg叶酸。随访4.5年期间,616人发生首次卒中。 

原始出处:

Xu RB, Kong X, Xu BP, et al. Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: effect of folic acid intervention. Am J Clin Nutr. 2017 Jan 25.

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    2017-02-10 ylzr123

    好文,值得点赞,值得拥有,值得收藏!

    0

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    2017-02-08 1771ae4158m

    学习一下很不错

    0

  4. 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level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Wed Feb 08 00:28:00 CST 2017, time=2017-02-08, status=1, ipAttribution=)]
    2017-02-08 1771ae4158m

    学习一下很不错

    0

  5. 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level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Wed Feb 08 00:28:00 CST 2017, time=2017-02-08, status=1, ipAttribution=)]
    2017-02-08 1771ae4158m

    学习一下很不错

    0

  6. 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level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Wed Feb 08 00:28:00 CST 2017, time=2017-02-08, status=1, ipAttribution=)]
    2017-02-08 1771ae4158m

    学习一下很不错

    0

  7. 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level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Wed Feb 08 00:28:00 CST 2017, time=2017-02-08, status=1, ipAttribution=)]
    2017-02-08 1771ae4158m

    学习一下很不错

    0

  8. 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    2017-02-08 1771ae4158m

    学习一下很不错

    0

  9. 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level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Wed Feb 08 00:28:00 CST 2017, time=2017-02-08, status=1, ipAttribution=)]
    2017-02-08 1771ae4158m

    学习一下很不错

    0

  10. 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