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JGH: 腰围与正常体重成人结直肠肿瘤风险的关系

2019-06-28 不详 MedSci原创

使用腰围(WC)衡量腹部肥胖与结肠直肠瘤形成(CRN)风险相关。本项研究旨在评估WC是否与CRN发生风险相关。

背景与目的
使用腰围(WC)衡量腹部肥胖与结肠直肠瘤形成(CRN)风险相关。本项研究旨在评估WC是否与CRN发生风险相关。

方法
研究人员对接受结肠镜检查作为健康检查的无症状正常体重(体重指数18.5-23 kg / m 2)患者进行横断面研究。

结果
在63057名受试者中,30498名是男性(平均年龄41.1岁),32559名是女性(平均年龄41.7岁)。WC各个四分位数的与整体CRN患病率男性分别为14.2%,15.5%,15.5%和18.7%,女生分别为7.4%,8.9%,9.4%和11.5%。WC各个四分位数与中晚期CRN(ACRN)的患病率男性为1.5%,1.3%,1.6%和2.1%,女性为1.0%,1.3%,1.2%和1.3%。在男性中,WC > 82 cm的整体CRN风险较高(HR:1.12,OR [95%置信区间,CI],1.22 [1.11-1.34])。

结论
本项研究表明即使体重正常,较大的WC与CRN风险相关。

原始出处:
Yoon Suk Jung. Et al. Association between Waist Circumference and Risk of Colorectal Neoplasia in Normal‐weight Adults. Journal of Gastroenterology and Hepatology .2019.

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    2020-04-27 bnjfy
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    2019-06-30 naiwu77
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    2019-06-28 329523732

    不错

    0

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