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JCEM:将小腿围加入代谢综合征组分对心血管风险的影响!

2018-01-16 xing.T MedSci原创

由此可见,与MetS的传统定义相比,将CC加入MetS组分有更高的心血管和全因死亡风险。

小腿围(CC)是一个有用的人体测量工具,但CC对代谢综合征(MetS)中心血管危险因素影响的研究十分有限。近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,研究人员目的是确定将CC加入到MetS组分是否与心血管、全因和癌症死亡率相关。

该研究采用1999-2002年的数据,研究人员分析了四种类型的MetS:腰部MetS(腰围增加以及四个MetS的组分中超过两个),小腿MetS(CC降低和四个MetS的组分中超过两个),WCR-MetS(腰围小腿比增加和四个MetS的组分中超过两个),以及CC+MetS(CC降低和五个MetS的组分中超过三个)。该研究的主要结局为通过四种MetS分类的病因特异风险比。

对于心血管疾病死亡,腰部MetS、小腿MetS、WCR-MetS和CC+MetS参与者调整后的风险比分别为1.867、1.871、1.949和2.306(P均<0.001)。值得注意的是,小腿MetS与血清CRP水平具有最强的正相关性,而WCR-MetS与胰岛素抵抗存在最强的正相关性。

由此可见,与MetS的传统定义相比,将CC加入MetS组分有更高的心血管和全因死亡风险。

原始出处:


Chen-Jung Wu,et al. Does the additional component of calf-circumference refine metabolic syndrome in Correlating with Cardiovascular Risk?J Clin Endocrinol Metab. 2017. https://doi.org/10.1210/jc.2017-02320

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    2018-01-24 jyzxjiangqin

    代谢综合征组分对心血管风险的影响.

    0

  5. 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  6. 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    2018-01-17 177200fc66m

    小腿围测量简单.不错

    0

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createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/23/557c1f19aaf5459a8405411e38903c4b.jpg, createdBy=dfc02088287, createdName=cscdliu, createdTime=Tue Jan 16 15:56:23 CST 2018, time=2018-01-16, status=1, ipAttribution=)]
    2018-01-16 1e0e5a1fm42(暂无匿称)

    henhao

    0

  8. 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    2018-01-16 有备才能无患

    小腿围(CC)是一个有用的人体测量工具.但CC对代谢综合征(MetS)中心血管危险因素影响的研究十分有限.近日.内分泌和代谢性疾病领域权威杂志JournalofClinicalEndocrinology&Metabolism上发表了一篇研究文章.研究人员目的是确定将CC加入到MetS组分是否与心血管.全因和癌症死亡率相关.

    0

  9. 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    2018-01-16 cscdliu

    学习了.谢谢

    0

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