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J Clin Periodontol:肥胖及非肥胖牙周炎患者牙周治疗前后血清RBP4的水平变化

2017-11-20 MedSci MedSci原创

本研究旨在评估精瘦与肥胖牙周炎(CP)患者牙周治疗前后血清RBP4的水平,并确定其余牙周炎可能的关联。此干预性研究共招募了112名精瘦和119名肥胖者。术前、术后三个月对牙周病患者进行牙周非手术治疗。评估患者的牙周、人体测量、生化指标及血清TNF-α、IL-6、hsCRP和RBP4的水平。结果显示,血清RBP4的水平与牙周炎的概率增加相关(OR 1.60;95% CI:1.02-2.50),显示C

本研究旨在评估精瘦与肥胖牙周炎(CP)患者牙周治疗前后血清RBP4的水平,并确定其余牙周炎可能的关联。

此干预性研究共招募了112名精瘦和119名肥胖者。术前、术后三个月对牙周病患者进行牙周非手术治疗。评估患者的牙周、人体测量、生化指标及血清TNF-α、IL-6、hsCRP和RBP4的水平。

结果显示,血清RBP4的水平与牙周炎的概率增加相关(OR 1.60;95% CI:1.02-2.50),显示CP患者RBP4的水平高于无CP的精瘦和肥胖人群(3.35 vs 3.06和3.74 vs 3.21)。牙周治疗后,RBP4与TNF-α的水平下降,牙周参数改善到相同的程度,除了探测深度(PD)≥4mm的牙齿数以外。多变量回归模型显示,PD≥4mm的牙齿数目与RBP4独立相关(β= 0.192)。

综上所述,该研究结果表明RBP4的水平与慢性牙周炎患者牙周治疗与否相关。

原始出处:

Martínez-Herrera M, Silvestre FJ, et al., Levels of serum retinol binding protein 4 before and after non-surgical periodontal treatment in lean and obese subjects: an interventional study. J Clin Periodontol. 2017 Nov 18. doi: 10.1111/jcpe.12840. 

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    2017-11-24 三生有幸9135

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    2017-11-23 三生有幸9135

    学习一下谢谢分享

    0

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    2017-11-22 三生有幸9135

    学习一下谢谢分享

    0

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    2017-11-21 三生有幸9135

    学习一下谢谢分享

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1726885, encodeId=d7621e26885f1, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri May 18 05:27:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263969, encodeId=d55326396945, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Fri Nov 24 16:02:32 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263640, encodeId=1a3126364086, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Thu Nov 23 15:17:08 CST 2017, time=2017-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263373, encodeId=4adc2633e3d9, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed Nov 22 15:52:54 CST 2017, time=2017-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450702, encodeId=f09c1450e02d9, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Nov 22 09:27:00 CST 2017, time=2017-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493506, encodeId=c53c1493506e2, content=<a href='/topic/show?id=dc4c6e51457' target=_blank style='color:#2F92EE;'>#牙周治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67514, encryptionId=dc4c6e51457, topicName=牙周治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc259064725, createdName=cooco, createdTime=Wed Nov 22 09:27:00 CST 2017, time=2017-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263127, encodeId=919a26312efc, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Tue Nov 21 15:38:16 CST 2017, time=2017-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263030, encodeId=8146263030c4, content=学习了.可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/07/07/d51783575d8d90eaa8b668d568aa6e50.jpg, createdBy=909f109204, createdName=liuweigang, createdTime=Tue Nov 21 08:41:01 CST 2017, time=2017-11-21, status=1, ipAttribution=)]
    2017-11-21 liuweigang

    学习了.可以

    0

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