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Crit Care Med:心脏手术后心输出量的心率修正!

2017-04-25 xing.T MedSci原创

超声心动图引导的心率优化可以显著增加心脏输出,相比于术后的临床衍生的起搏设置。最佳心率应根据每个病人实现个体化,总的等容时间是灵敏度最高的超声心动图指标来确定最佳的血流动力学。

心输出量不足与心脏手术后的预后较差有关,通常通过使用正性肌力药、容积复苏和起搏来进行调整。超声指导下的起博优化主要用于门诊患者,通过使用不同的变量,包括总的等容时间和Tei指数。近日,危重病医学领域权威杂志Critical Care Medicine上发表了一篇研究文章,研究人员旨在明确心率对围手术期心脏电机械学、心输出量、每搏量的影响。

该研究为观察性研究,是心胸外科成人重症监护室完成。以24个连续就诊的心脏手术后患者为研究对象。患者起搏器的设置是由治疗麻醉师根据血流动力学参数完成的,回到重症监护4小时内,他们重新使用经胸超声心动图进行评估。研究人员进行了一个全面的基线超声心动图研究,通过临床医生设置RR间隔和心率从70到110次/分,增量为10次/分。皮尔森相关系数被用来评估测量指标之间的相关性。

79%使用超声心动图引导起搏器优化的患者心脏输出量和心脏指数显着增加(分别为2.21L/min±0.97和1.2L/min/m2±0.52)。超声心动图驱动的心脏输出优化方案导致在整体人群中总的等容时间减少,同时心输出量和心脏指数增加(P<0.001)。整体人群中RR间期和心搏量、心输出量或心脏指数之间没有一致的相关性。在所有组中左心室总的等容时间、每搏量、心输出量和心脏指数之间被发现具有强烈的负相关关系。

超声心动图引导的心率优化可以显著增加心脏输出,相比于术后的临床衍生的起搏设置。最佳心率应根据每个病人实现个体化,总的等容时间是灵敏度最高的超声心动图指标来确定最佳的血流动力学。

原始出处:

Tavazzi, Guido, et al. Heart Rate Modification of Cardiac Output Following Cardiac Surgery: The Importance of Cardiac Time Intervals.Critical Care Medicine.2017. http://journals.lww.com/ccmjournal/Abstract/publishahead/Heart_Rate_Modification_of_Cardiac_Output.96624.aspx

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  1. [GetPortalCommentsPageByObjectIdResponse(id=194508, encodeId=fb54194508d4, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat May 06 10:01:09 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194147, encodeId=534919414e6c, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Fri May 05 12:41:30 CST 2017, time=2017-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1370509, encodeId=7e9e13e0509a1, content=<a href='/topic/show?id=fb68519e80e' target=_blank style='color:#2F92EE;'>#心输出量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51978, encryptionId=fb68519e80e, topicName=心输出量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68f2317, createdName=天堂的云, createdTime=Thu Apr 27 10:49:00 CST 2017, time=2017-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607431, encodeId=4333160e431bc, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Apr 27 10:49:00 CST 2017, time=2017-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190947, encodeId=cf6219094e35, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦……, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Thu Apr 27 06:12:25 CST 2017, time=2017-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190669, encodeId=534019066939, content=文章很好,拜读了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Apr 26 08:06:28 CST 2017, time=2017-04-26, status=1, ipAttribution=)]
    2017-05-06 1e10c84am36(暂无匿称)

    文章不错,值得拜读

    0

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    2017-05-05 cuiyejia

    学习了,谢谢

    0

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    2017-04-27 ylzr123

    认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦……

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=194508, encodeId=fb54194508d4, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat May 06 10:01:09 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=194147, encodeId=534919414e6c, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28761705280, createdName=cuiyejia, createdTime=Fri May 05 12:41:30 CST 2017, time=2017-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1370509, encodeId=7e9e13e0509a1, content=<a href='/topic/show?id=fb68519e80e' target=_blank style='color:#2F92EE;'>#心输出量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51978, encryptionId=fb68519e80e, topicName=心输出量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68f2317, createdName=天堂的云, createdTime=Thu Apr 27 10:49:00 CST 2017, time=2017-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607431, encodeId=4333160e431bc, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Apr 27 10:49:00 CST 2017, time=2017-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190947, encodeId=cf6219094e35, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦……, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Thu Apr 27 06:12:25 CST 2017, time=2017-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=190669, encodeId=534019066939, content=文章很好,拜读了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Apr 26 08:06:28 CST 2017, time=2017-04-26, status=1, ipAttribution=)]
    2017-04-26 1e10c84am36(暂无匿称)

    文章很好,拜读了

    0

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