Baidu
map

JACC:高血糖大大推进亚临床心衰的进展!

2022-06-15 MedSci原创 MedSci原创

在亚临床心衰的老年人中,控制不佳的糖尿病与心衰进展的高风险密切相关

在全球范围内,糖尿病和心力衰竭(HF)都非常普遍,而且这两种疾病之间存在很强的相关性。基本上,每3个心衰患者中就有1个合并糖尿病,此外,糖尿病使心衰风险升高了2-5倍。但是,糖尿病对从亚临床心衰阶段进展成显性心衰的影响尚不明确。

该研究目的是归纳糖尿病对亚临床心衰(A期或B期)至显性心衰进展过程的影响。

纳入了参与ARIC研究(2011-2013)的4774位亚临床心衰(A期:1551人,B期:3223人)。研究人员在各期(A期或B期)受试者中分别评估了糖尿病和血糖控制(糖化血红蛋白[HbA1c]<7% vs ≥7%)与心衰进展的相关性,以及心衰分期的跨类别(A vs B)、糖尿病和血糖控制与心衰事件的关系。


糖尿病和亚临床心衰与临床心衰事件的关系

4774位受试者,平均75.4岁,58%的女性,20%的黑人。中位随访了8.6年,共记录了470例心衰事件。对于B期受试者,与血糖控制良好或无糖尿病的个体相比,HbA1c≥7%的个体发生临床心衰时往往更年轻(平均年龄:80岁 vs 83岁 vs 82岁,p<0.001)。与A期受试者相比,HbA1c≥7%与B期受试者心衰风险的相关性更强(HR:1.83 vs 1.52)。在亚临床心衰和HbA1C的交叉分类中,B期和HbA1c≥7%的受试者的心衰进展风险显著高于无糖尿病的A期亚临床心衰个体(HR 7.56)。


根据HbA1c、糖尿病和亚临床心衰分类的心衰发生率

总而言之,在亚临床心衰的老年人中,控制不佳的糖尿病与心衰进展的高风险密切相关。该研究结果强调了对亚临床心衰患者血糖控制的重要性。

 

原始出处:

Echouffo-Tcheugui Justin B,Ndumele Chiadi E,Zhang Sui et al. Diabetes and Progression of Heart?Failure: The Atherosclerosis Risk In Communities (ARIC) Study.[J] .J Am Coll Cardiol, 2022, 79: 2285-2293.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1855065, encodeId=0d8c185506527, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Jan 21 11:22:34 CST 2023, time=2023-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1261236, encodeId=fd31126123651, content=<a href='/topic/show?id=30c6102e2607' target=_blank style='color:#2F92EE;'>#高血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102726, encryptionId=30c6102e2607, topicName=高血糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Jun 16 11:22:34 CST 2022, time=2022-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326958, encodeId=5af81326958eb, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Thu Jun 16 11:22:34 CST 2022, time=2022-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1247317, encodeId=46e3124e3179b, content=大家一般关心疾病,但是亚临床更重要,这是疾病防控方向的前移,各类疾病都是这样。如亚临床甲减,亚临床心肌损伤,亚临床心衰等, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=jingjing, createdTime=Tue Jun 14 23:22:34 CST 2022, time=2022-06-14, status=1, ipAttribution=)]
    2023-01-21 hbwxf
  2. [GetPortalCommentsPageByObjectIdResponse(id=1855065, encodeId=0d8c185506527, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Jan 21 11:22:34 CST 2023, time=2023-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1261236, encodeId=fd31126123651, content=<a href='/topic/show?id=30c6102e2607' target=_blank style='color:#2F92EE;'>#高血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102726, encryptionId=30c6102e2607, topicName=高血糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Jun 16 11:22:34 CST 2022, time=2022-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326958, encodeId=5af81326958eb, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Thu Jun 16 11:22:34 CST 2022, time=2022-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1247317, encodeId=46e3124e3179b, content=大家一般关心疾病,但是亚临床更重要,这是疾病防控方向的前移,各类疾病都是这样。如亚临床甲减,亚临床心肌损伤,亚临床心衰等, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=jingjing, createdTime=Tue Jun 14 23:22:34 CST 2022, time=2022-06-14, status=1, ipAttribution=)]
    2022-06-16 hbwxf
  3. [GetPortalCommentsPageByObjectIdResponse(id=1855065, encodeId=0d8c185506527, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Jan 21 11:22:34 CST 2023, time=2023-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1261236, encodeId=fd31126123651, content=<a href='/topic/show?id=30c6102e2607' target=_blank style='color:#2F92EE;'>#高血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102726, encryptionId=30c6102e2607, topicName=高血糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Jun 16 11:22:34 CST 2022, time=2022-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326958, encodeId=5af81326958eb, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Thu Jun 16 11:22:34 CST 2022, time=2022-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1247317, encodeId=46e3124e3179b, content=大家一般关心疾病,但是亚临床更重要,这是疾病防控方向的前移,各类疾病都是这样。如亚临床甲减,亚临床心肌损伤,亚临床心衰等, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=jingjing, createdTime=Tue Jun 14 23:22:34 CST 2022, time=2022-06-14, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1855065, encodeId=0d8c185506527, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Jan 21 11:22:34 CST 2023, time=2023-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1261236, encodeId=fd31126123651, content=<a href='/topic/show?id=30c6102e2607' target=_blank style='color:#2F92EE;'>#高血糖#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102726, encryptionId=30c6102e2607, topicName=高血糖)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Jun 16 11:22:34 CST 2022, time=2022-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326958, encodeId=5af81326958eb, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Thu Jun 16 11:22:34 CST 2022, time=2022-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1247317, encodeId=46e3124e3179b, content=大家一般关心疾病,但是亚临床更重要,这是疾病防控方向的前移,各类疾病都是这样。如亚临床甲减,亚临床心肌损伤,亚临床心衰等, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=jingjing, createdTime=Tue Jun 14 23:22:34 CST 2022, time=2022-06-14, status=1, ipAttribution=)]
    2022-06-14 jingjing

    大家一般关心疾病,但是亚临床更重要,这是疾病防控方向的前移,各类疾病都是这样。如亚临床甲减,亚临床心肌损伤,亚临床心衰等

    0

相关资讯

Cardiovasc Diabetol:HbA1c水平有助于预测重症监护室患者的死亡风险

HbA1c 水平≥5.7g%(糖尿病前期和糖尿病)与 ICCU 患者更差的预后相关

Diabetologia:长期生活方式干预对糖尿病前期成人体重和心脏代谢健康标志物的年龄和性别特异性影响

作为肥胖的一线治疗选择,生活方式干预在几项大规模研究中被证明有助于减肥和改善心脏代谢健康指标。

Eur J Endocrinol:小RNA在自身免疫性和非自身免疫性糖尿病和对照组中差异表达

LADA的病理生理学和遗传特征远不如它的同类1型和2型糖尿病那样为人所知。

Cancers :糖尿病严重程度和病死率与肺鳞癌的关系

糖尿病可导致心血管疾病、肾病、视网膜病变、外周血管疾病、中风、神经病变和代谢并发症。最近的研究证实,糖尿病与痴呆症、听力损失和特定形式的癌症有关。

久坐对身体的伤害远比想象中大!柳叶刀子刊:每天久坐6小时,增加12种慢性疾病风险

柳叶刀子刊:每天久坐时间超过6小时,与12种常见的慢性疾病风险升高有关;但如果将久坐用不同强度的身体活动代替时,可降低因久坐导致的常见慢性病发生,且身体活动强度越大,可预防慢性病的种类越多。

Br J Cancer :家族史、肥胖、泌尿系统因素和糖尿病药物与前列腺癌诊断风险的关系

有新的证据表明,用于治疗糖尿病的药物与包括PC在内的一系列恶性肿瘤的风险有关。

Baidu
map
Baidu
map
Baidu
map