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Prostate Cancer P D:一个基于国家癌症数据库的回顾分析:2004年到2013年前列腺癌IIA阶段放射疗法运用趋势情况

2017-04-13 AlexYang MedSci原创

最近的研究展现了在过去几十年中,放射疗法治疗前列腺癌的方法利用正在减少,更加保守的全面治疗方法同样存在减少趋势。最近,有研究人员对在2004年到2013年,这种减少的趋势是否持续以及各种不同放射疗法的利用的变化情况进行了研究。研究人员利用国家癌症数据库资料进行了一项回顾性研究。研究鉴定了在2003到2013年具有充足治疗信息并且被诊断为前列腺癌IIA阶段的706877名病人,并运用逻辑回归模型去评

最近的研究展现了在过去几十年中,放射疗法治疗前列腺癌的方法利用正在减少,更加保守的全面治疗方法同样存在减少趋势。最近,有研究人员对在2004年到2013年,这种减少的趋势是否持续以及各种不同放射疗法的利用的变化情况进行了研究。

研究人员利用国家癌症数据库资料进行了一项回顾性研究。研究鉴定了在2003到2013年具有充足治疗信息并且被诊断为前列腺癌IIA阶段的706877名病人,并运用逻辑回归模型去评估放射疗法利用的年度趋势。研究结果发现,从2004到2013年,与其它治疗方法比较,放射疗法的利用显着降低,从2004年的54.4%到2013年的34.5%。外离子束放射疗法(EBRT)的利用从2004年的27.1%减少到2013年的25.0%,并且短距离放射治疗从2004年的19.7%下降到2013年的6.1%。另外,组合疗法也从2004年的6.8%下降到2013年的2.6%。然而,当只考虑放射治疗这个范围时,EBRT的利用率从2004年的50.6%稳定的上升到2013年的74.0%,而短距离放射治疗从2004年的36.7%下降到2013年的18.2%。最后,尽管病人接受组合疗法在2004到2009年是降低的,但是在2009到2013年利用率有小程度的上升,即从8.3%到8.5%。

最后,研究人员指出,从2004年开始,前列腺癌治疗的放射疗法的利用率是显着降低的,包括每一种放射疗法手段。但是对病人接受用放射疗法群体中,EBRT的利用增加了,但是短距离放射疗法利用降低了。这些数据可以鼓励人们进一步研究这些趋势的原因及怎么样影响病人的治疗。

原始出处:

T Malouff, N W Mathy, S Marsh et al. Trends in the use of radiation therapy for stage IIA prostate cancer from 2004 to 2013: a retrospective analysis using the National Cancer Database. Prostate Cancer P D. 11 April 2017. doi:10.1038/pcan.2017.15.

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    2017-04-15 虈亣靌

    学习了很好的内容

    0

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    2017-04-14 lsndxfj
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    2017-04-14 sunylz

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匹兹堡大学癌症研究所(UPCI)的科学家在美国华盛顿特区的 AACR 年会上报道,保护染色体末端的 DNA 端粒长度可以预测癌症的风险并成为未来治疗的潜在靶标。

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